High-intensity focused ultrasound combined with herpes simplex virus thymidine kinase gene-loaded ultrasound-targeted microbubbles improved the survival of rabbits with VX2 liver tumor

Journal of Gene Medicine

Volumn 14, Issue 9-10, 2012, Pages 570-579

  Zhou, Shi Ji ^a   Li, Sheng Wei ^a   Wang, Ji Jian ^a   Liu, Zuo Jin ^a   Yin, Guo Bing ^a   Gong, Jian Ping ^a   Liu, Chang An ^a  

^a THE SECOND AFFILIATED HOSPITAL OF CHONGQING MEDICAL UNIVERSITY   (China)

Author keywords

Gene delivery; High intensity focused ultrasound; HSV TK; Microbubbles; VX2 liver tumor

Indexed keywords

HERPESVIRUS VECTOR; MESSENGER RNA; THYMIDINE KINASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER INHIBITION; CONTROLLED STUDY; GENE EXPRESSION PROFILING; GENETIC TRANSFECTION; HERPES SIMPLEX VIRUS; HERPES SIMPLEX VIRUS THYMIDINE KINASE GENE LOADED ULTRASOUND TARGETED MICROBUBBLE; HIGH INTENSITY FOCUSED ULTRASOUND; IMMUNOHISTOCHEMISTRY; IN VIVO STUDY; LIVER TUMOR; MICROBUBBLE; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RABBIT; REAL TIME POLYMERASE CHAIN REACTION; SUICIDE GENE; SURVIVAL TIME; TREATMENT OUTCOME; TUMOR ABLATION; TUMOR GROWTH; TUMOR MODEL; ULTRASOUND THERAPY; VIRAL GENE DELIVERY SYSTEM; WESTERN BLOTTING;

ANIMALS; APOPTOSIS; GENE EXPRESSION; GENETIC THERAPY; LIVER NEOPLASMS, EXPERIMENTAL; MICROBUBBLES; RABBITS; SIMPLEXVIRUS; THYMIDINE KINASE; TREATMENT OUTCOME; ULTRASOUND, HIGH-INTENSITY FOCUSED, TRANSRECTAL;

ANIMALIA; ORYCTOLAGUS CUNICULUS; SIMPLEXVIRUS;

EID: 84868146838     PISSN: 1099498X     EISSN: 15212254     Source Type: Journal    
DOI: 10.1002/jgm.2668     Document Type: Article

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