The pros and cons of immunomodulatory IL-10 gene therapy with recombinant AAV in a Cftr-/--dependent allergy mouse model

Gene Therapy

Volumn 16, Issue 2, 2009, Pages 172-183

  Mueller, C ^a   Braag, S A ^a   Martino, A T ^b   Tang, Q ^a   Campbell Thompson, M ^c   Flotte, T R ^a  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^c UNIVERSITY OF FLORIDA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN E; INTERLEUKIN 10; INTERLEUKIN 13; INTERLEUKIN 4; INTERLEUKIN 5; PARVOVIRUS VECTOR; TRANSMEMBRANE CONDUCTANCE REGULATOR; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; CYTOKINE; FUNGUS ANTIGEN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASPERGILLUS FUMIGATUS; BRONCHOPULMONARY ASPERGILLOMA; CONTROLLED STUDY; CYSTIC FIBROSIS; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DOSE RESPONSE; DOWN REGULATION; DRUG DOSE COMPARISON; EOSINOPHILIA; HEPATITIS; IMMUNOGLOBULIN BLOOD LEVEL; IMMUNOMODULATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; SKELETAL MUSCLE; SPLENOMEGALY; TH1 CELL; TH2 CELL; THROMBOCYTOPENIA; VIRAL GENE THERAPY; VIRUS RECOMBINANT; ANIMAL; ASPERGILLOSIS, ALLERGIC BRONCHOPULMONARY; BIOSYNTHESIS; BLOOD; C57BL MOUSE; COMPLICATION; DEFICIENCY; DEPENDOPARVOVIRUS; DISEASE MODEL; EVALUATION STUDY; GENE THERAPY; GENETICS; IMMUNOLOGY; KNOCKOUT MOUSE; LUNG; PATHOLOGY;

ANIMALS; ANTIGENS, FUNGAL; ASPERGILLOSIS, ALLERGIC BRONCHOPULMONARY; ASPERGILLUS FUMIGATUS; CYSTIC FIBROSIS; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; CYTOKINES; DEPENDOVIRUS; DISEASE MODELS, ANIMAL; GENE THERAPY; IMMUNOGLOBULIN E; INTERLEUKIN-10; LUNG; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; SPLENOMEGALY; THROMBOCYTOPENIA; GENETIC THERAPY;

ASPERGILLUS FUMIGATUS; MUS;

EID: 60449107858     PISSN: 09697128     EISSN: 14765462     Source Type: Journal    
DOI: 10.1038/gt.2008.156     Document Type: Article

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