HERG 1b is critical for human cardiac repolarization

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 50, 2014, Pages 18073-18077

  Jones, David K ^a   Liu, Fang ^a   Vaidyanathan, Ravi ^a   Eckhardt, L Lee ^a   Trudeau, Matthew C ^b   Robertson, Gail A ^a  

^a UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^b UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

Author keywords

Arrhythmia; Early afterdepolarization; HERG; KCNH2; Long QT syndrome

Indexed keywords

ACTIN; MESSENGER RNA; POTASSIUM CHANNEL HERG; POTASSIUM CHANNEL HERG 1B; SHORT HAIRPIN RNA; UNCLASSIFIED DRUG; ERG1 POTASSIUM CHANNEL; SMALL INTERFERING RNA;

ACTION POTENTIAL; ACTION POTENTIAL DURATION; ARTICLE; CELL MEMBRANE; CONTROLLED STUDY; EMBRYO; GENETIC TRANSCRIPTION; HEART ARRHYTHMIA; HEART DEPOLARIZATION; HEART MUSCLE CELL; HEART REPOLARIZATION; HETEROLOGOUS EXPRESSION; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IMMUNOCYTOCHEMISTRY; LONG QT SYNDROME; MEMBRANE CURRENT; PLURIPOTENT STEM CELL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; ANALYSIS OF VARIANCE; CELL POLARITY; GENE SILENCING; GENETICS; HEART VENTRICLE FUNCTION; IMMUNOHISTOCHEMISTRY; MEMBRANE POTENTIAL; METABOLISM; PHYSIOLOGY; REAL TIME POLYMERASE CHAIN REACTION;

ACTION POTENTIALS; ANALYSIS OF VARIANCE; CELL POLARITY; ETHER-A-GO-GO POTASSIUM CHANNELS; GENE KNOCKDOWN TECHNIQUES; HUMANS; IMMUNOHISTOCHEMISTRY; MEMBRANE POTENTIALS; MYOCYTES, CARDIAC; REAL-TIME POLYMERASE CHAIN REACTION; RNA, SMALL INTERFERING; VENTRICULAR FUNCTION;

EID: 84919372254     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1414945111     Document Type: Article

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