Prolongation of the QT interval and the sudden infant death syndrome

New England Journal of Medicine

Volumn 338, Issue 24, 1998, Pages 1709-1714

  Schwartz, Peter John ^a,h   Stramba Badiale, Marco ^b   Segantini, Alessandro ^b   Austoni, Paola ^c   Bosi, Giuliano ^d   Giorgetti, Roberto ^e   Grancini, Fabio ^b   Marni, Ernesto Diego ^a   Perticone, Francesco ^f   Rosti, Dario ^g   Salice, Patrizia ^g  

^a UNIVERSITY OF PAVIA   (Italy)

^b UNIVERSITY OF MILAN   (Italy)

^c OSPEDALE NIGUARDA CA GRANDA   (Italy)

^d UNIVERSITY OF FERRARA   (Italy)

^e Ospedale Galmarini   (Italy)

^f UNIVERSITY MEDITERRANEA OF REGGIO CALABRIA   (Italy)

^g REGINA ELENA NATIONAL CANCER INSTITUTE   (Italy)

^h FONDAZIONE IRCCS POLICLINICO SAN MATTEO   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CLINICAL TRIAL; CONTROLLED STUDY; DIAGNOSTIC VALUE; DISEASE ASSOCIATION; EARLY DIAGNOSIS; ELECTROCARDIOGRAM; FEMALE; HUMAN; INFANT; LONG QT SYNDROME; MAJOR CLINICAL STUDY; MALE; PATHOGENESIS; PREDICTION; PRIORITY JOURNAL; RISK ASSESSMENT; RISK FACTOR; SCREENING TEST; SUDDEN INFANT DEATH SYNDROME;

ELECTROCARDIOGRAPHY; FEMALE; HUMANS; INFANT, NEWBORN; LONG QT SYNDROME; MALE; NEONATAL SCREENING; PROSPECTIVE STUDIES; REFERENCE VALUES; SUDDEN INFANT DEATH;

EID: 17144450747     PISSN: 00284793     EISSN: None     Source Type: Journal    
DOI: 10.1056/NEJM199806113382401     Document Type: Article

References (41)

1. Dwyer T, Ponsonby AL. SIDS epidemiology and incidence. Pediatr Ann 1995;24:350-2.
2. Dwyer T, Ponsonby AL, Blizzard L, Newman NM, Cochrane JA. The contribution of changes in the prevalence of prone sleeping position to the decline in sudden infant death syndrome in Tasmania. JAMA 1995;273:783-9.
3. Schwartz LZ. The origin of maternal feelings of guilt in SIDS: relationship with the normal psychosocial reactions of maternity. Ann N Y Acad Sci 1988;533:132-44.
4. Schwartz PJ. The quest for the mechanisms of the sudden infant death syndrome: doubts and progress. Circulation 1987;75:677-83.
5. Idem. The sudden infant death syndrome. In: Scarpelli EM, Cosmi EV, eds. Reviews in perinatal medicine. Vol. 4. New York: Raven Press, 1981: 475-524.
6. Schwartz PJ, Southall DP, Valdes-Dapena M, eds. The sudden infant death syndrome: cardiac and respiratory mechanisms and interventions. Ann NY Acad Sci 1988;533.
7. Schwartz PJ. Cardiac sympathetic innervation and the sudden infant death syndrome: a possible pathogenetic link. Am J Med 1976;60:167-72.
8. Schwartz PJ, Priori SG. Sympathetic nervous system and cardiac arrhythmias. In: Zipes DP, Jalife J, eds. Cardiac electrophysiology: from cell to bedside. Philadelphia: W.B. Saunders, 1990:330-43.
9. Walsh SZ. Electrocardiographic intervals during the first week of life. Am Heart J 1963;66:36-41.
10. Bazett HC. An analysis of the time-relations of electrocardiograms. Heart 1920;7:353-70.
11. Bergman AB, Beckwith JB, Ray CG, eds. Sudden infant death syndrome: proceedings. Seattle: University of Washington Press, 1970.
12. Schwartz PJ, Montemerlo M, Facchini M, et al. The QT interval throughout the first six months of life: a prospective study. Circulation 1982;66:496-501.
13. Davignon A, Rautaharju B, Boisselle E, Soumis F, Megelas M, Choquette A. Normal electrocardiogram standards for infants and children. Pediatr Cardiol 1980;1:123-31.
14. Alimurung MM, Joseph LG, Craige E, Massell BF. The Q-T interval in normal infants and children. Circulation 1950;1:1329-7.
15. McCammon RW. A longitudinal study of electrocardiographs intervals in healthy children. Acta Paediatr Suppl 1961;126:3-54.
16. Southall DP, Arrowsmith WA, Stebbens V, Alexander JR. QT interval measurements before sudden infant death syndrome. Arch Dis Child 1986; 61:327-33.
17. Merri M, Benhorin J, Alberti M, Locati E, Moss AJ. Electrocardiographic quantitation of ventricular repolarization. Circulation 1989;80: 1301-8.
18. Stramba-Badiale M, Spagnolo D, Bosi G, Schwartz PJ. Are gender differences in QTc present at birth? Am J Cardiol 1995;75:1277-8.
19. Schwartz PJ, Moss AJ, Vincent GM, Crampton RS. Diagnostic criteria for the long QT syndrome: an update. Circulation 1993;88:782-4.
20. Fleming PJ, Gilbert R, Azaz Y, et al. Interaction between bedding and sleeping position in the sudden infant death syndrome: a population based case-control study. BMJ 1990;301:85-9.
21. Mitchell EA, Taylor BJ, Ford RPK, et al. Four modifiable and other major risk factors for cot death: the New Zealand study. J Paediatr Child Health 1992;28:Suppl 1:S3-S8.
22. Kelly DH, Shannon DC, Liberthson RR. The role of the QT interval in the sudden infant death syndrome. Circulation 1977;55:633-5.
23. Steinschneider A. Sudden infant death syndrome and prolongation of the QT interval. Am J Dis Child 1978;132:688-91.
24. Haddad GG, Epstein MAF, Epstein RA, Mazza NM, Mellins RB, Krongrad E. The QT interval in aborted sudden infant death syndrome infants. Pediatr Res 1979;13:136-8.
25. Montague TJ, Finley JP, Mukelabai K, et al. Cardiac rhythm, rate and ventricular repolarization properties in infants at risk for sudden infant death syndrome: comparison with age-and sex-matched control infants. Am J Cardiol 1984;54:301-7.
26. Schwartz PJ, Segantini A. Cardiac innervation, neonatal electrocardiography, and SIDS: a key for a novel preventive strategy? Ann N Y Acad Sci 1988;533:210-20.
27. Sadeh D, Shannon DC, Abboud S, Saul JP, Akselrod S, Cohen RJ. Altered cardiac repolarization in some victims of sudden infant death syndrome. N Engl J Med 1987;317:1501-5.
28. Wynn VT, Southall DP. Normal relation between heart rate and cardiac repolarisation in sudden infant death syndrome. Br Heart J 1992;67: 84-8.
29. Butrous GS, Schwartz PJ, eds. Clinical aspects of ventricular repolarization. London: Farrand Press, 1989.
30. Schwartz PJ, Locati EH, Napolitano C, Priori SG. The long QT syndrome In: Zipes DP, Jalife J, eds. Cardiac electrophysiology: from cell to bedside. 2nd ed. Philadelphia: W.B. Saunders, 1995:788-811.
31. Schwartz PJ, Wolf S. QT interval prolongation as predictor of sudden death in patients with myocardial infarction. Circulation 1978;57:1074-7.
32. Algra A, Tijssen JGP, Roelandt JRTC, Pool J, Lubsen J. QTc prolongation measured by standard 12-lead electrocardiography is an independent risk factor for sudden death due to cardiac arrest. Circulation 1991;83: 1888-94.
33. Schouten EG, Dekker JM, Meppelink P, Kok FJ, Vandenbroucke JP, Pool J. QT interval prolongation predicts cardiovascular mortality in an apparently healthy population. Circulation 1991;84:1516-23
34. Stramba-Badiale M, Goulene K, Schwartz PJ. Effects of β-adrenergic blockade on dispersion of ventricular repolarization in newborn infants with prolonged QT interval. Am Heart J 1997;134:406-10.
35. Malfatto G, Rosen TS, Steinberg SF, et al. Sympathetic neural modulation of cardiac impulse initiation and repolarization in the newborn rat. Circ Res 1990;66:427-37.
36. Stramba-Badiale M, Lazzarotti M, Schwartz PJ. Development of cardiac innervation, ventricular fibrillation, and sudden infant death syndrome. Am J Physiol 1992;263:H1514-H1522.
37. Gootman PM, ed. Developmental neurobiology of the autonomic nervous system. Clifton, N.J.: Humana Press, 1986.
38. Schwartz PJ. Idiopathic long QT syndrome: progress and questions. Am Heart J 1985;109:399-411.
39. Priori SG, Napolitano C, Paganini V, Cantù F, Schwartz PJ. Molecular biology of the long QT syndrome: impact on management. Pacing Clin Electrophysiol 1997;20:2052-7.
40. Romano C, Gemme G, Pongiglione R. Aritmie cardiache rare dell'età pediatrica. Clin Pediatr 1963;45:656-83.
41. Priori SG, Schwartz PJ, Napolitano C, et al. A recessive variant of the Romano-Ward long QT syndrome? Circulation (in press).