Ionic mechanisms limiting cardiac repolarization reserve in humans compared to dogs

Journal of Physiology

Volumn 591, Issue 17, 2013, Pages 4189-4206

  Jost, Norbert ^a,b   Virág, László ^b   Comtois, Philippe ^e,f   Ördög, Balázs ^b,e   Szuts, Viktória ^b   Seprényi, György ^b   Bitay, Miklós ^b   Kohajda, Zsófia ^a   Koncz, István ^b   Nagy, Norbert ^a   Szél, Tamás ^a   Magyar, János ^c   Kovács, Mária ^b   Puskás, László G ^a   Lengyel, Csaba ^b   Wettwer, Erich ^d   Ravens, Ursula ^d   Nánási, Péter P ^c   Papp, Julius G ^a,b   Varró, András ^a,b   Nattel, Stanley ^e,f   more..

^a INSTITUTE OF EXPERIMENTAL MEDICINE   (Hungary)

^b UNIVERSITY OF SZEGED   (Hungary)

^c UNIVERSITY OF DEBRECEN   (Hungary)

^d DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

^e UNIVERSITÉ DE MONTRÉAL   (Canada)

^f MONTREAL HEART INSTITUTE   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

BACL2; CALCIUM CHANNEL L TYPE; DELAYED RECTIFIER POTASSIUM CHANNEL; DOFETILIDE; INWARDLY RECTIFYING POTASSIUM CHANNEL SUBUNIT KIR2.1; MESSENGER RNA; N [3 HYDROXY 2,2 DIMETHYL 6 (4,4,4 TRIFLUOROBUTOXY)CHROMAN 4 YL] N METHYLMETHANESULFONAMIDE; POTASSIUM CHANNEL BLOCKING AGENT; POTASSIUM CHANNEL KCNE1; POTASSIUM CHANNEL KVLQT1; TRANSCRIPTION FACTOR ERG; UNCLASSIFIED DRUG; CALCIUM; POTASSIUM; POTASSIUM CHANNEL; SODIUM; SODIUM CALCIUM EXCHANGE PROTEIN;

ACTION POTENTIAL; ACTION POTENTIAL DURATION; ANIMAL TISSUE; ARTICLE; CALCIUM L TYPE CURRENT; CONTROLLED STUDY; DOG; FEMALE; HEART MUSCLE CELL; HEART REPOLARIZATION; HEART VENTRICLE; HUMAN; HUMAN TISSUE; HUMAN VERSUS ANIMAL COMPARISON; IMMUNOHISTOCHEMISTRY; INWARD RECTIFIER POTASSIUM CURRENT; ION CURRENT; MALE; MATHEMATICAL MODEL; MICROELECTRODE; MOLECULAR BIOLOGY; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAPID DELAYED RECTIFIER POTASSIUM CURRENT; SLOW DELAYED RECTIFIER POTASSIUM CURRENT; SODIUM CALCIUM EXCHANGE; TRANSIENT OUTWARD CURRENT; ADULT; ANIMAL; BIOLOGICAL MODEL; CELL CULTURE; GENETICS; HEART; ION TRANSPORT; METABOLISM; MIDDLE AGED; PHYSIOLOGY; SPECIES DIFFERENCE;

ACTION POTENTIALS; ADULT; ANIMALS; CALCIUM; CELLS, CULTURED; DOGS; FEMALE; HEART; HUMANS; ION TRANSPORT; MALE; MIDDLE AGED; MODELS, CARDIOVASCULAR; MYOCYTES, CARDIAC; POTASSIUM; POTASSIUM CHANNELS; RNA, MESSENGER; SODIUM; SODIUM-CALCIUM EXCHANGER; SPECIES SPECIFICITY;

EID: 84883281759     PISSN: 00223751     EISSN: 14697793     Source Type: Journal    
DOI: 10.1113/jphysiol.2013.261198     Document Type: Article

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