hERG1a/1b heteromeric currents exhibit amplified attenuation of inactivation in variant 1 short QT syndrome

Biochemical and Biophysical Research Communications

Volumn 386, Issue 1, 2009, Pages 111-117

  McPate, M J ^a   Zhang, H ^b   Cordeiro, J M ^c   Dempsey, C E ^d   Witchel, H J ^a   Hancox, J C ^a  

^a SCHOOL OF MEDICAL SCIENCES   (United Kingdom)

^b UNIVERSITY OF MANCHESTER   (United Kingdom)

^c MASONIC MEDICAL RESEARCH LABORATORY   (United States)

^d UNIVERSITY OF BRISTOL   (United Kingdom)

Author keywords

Channelopathy; hERG; hERG1a 1b; hERG1b; QT interval; Rapid delayed rectifier; Short QT syndrome

Indexed keywords

POTASSIUM CHANNEL HERG; POTASSIUM CHANNEL HERG 1A; POTASSIUM CHANNEL HERG 1B; UNCLASSIFIED DRUG;

ACTION POTENTIAL; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; ELECTRIC POTENTIAL; ELECTROPHYSIOLOGY; GENE MUTATION; NONHUMAN; POTASSIUM CURRENT; PRIORITY JOURNAL; PROTEIN EXPRESSION; SHORT QT SYNDROME; VOLTAGE CLAMP;

ARRHYTHMIAS, CARDIAC; CELL LINE; ETHER-A-GO-GO POTASSIUM CHANNELS; HUMANS; MUTATION;

EID: 67649229598     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2009.05.134     Document Type: Article

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