Retinal pathway origins of the pattern electroretinogram (PERG)

Investigative Ophthalmology and Visual Science

Volumn 52, Issue 12, 2011, Pages 8571-8584

  Luo, Xunda ^a,b   Frishman, Laura J ^a  

^a UNIVERSITY OF HOUSTON   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2,3 PIPERIDINECARBOXYLIC ACID; CARBOXYLIC ACID DERIVATIVE; TETRODOTOXIN; UNCLASSIFIED DRUG;

AMPLITUDE MODULATION; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; B WAVE; CONTROLLED STUDY; ELECTRORETINOGRAM; GLAUCOMA; NERVE CELL STIMULATION; NONHUMAN; PATTERN ELECTRORETINOGRAM; PHOTOPIC VISION; PRIORITY JOURNAL; RETINA GANGLION CELL; RETINAL PATHWAY ORIGIN; STEADY STATE; STIMULUS RESPONSE; VISUAL STIMULATION; VISUAL SYSTEM PARAMETERS;

ACTION POTENTIALS; ANIMALS; COMPUTER SIMULATION; DISEASE MODELS, ANIMAL; ELECTRORETINOGRAPHY; GLAUCOMA; INTRAVITREAL INJECTIONS; MACACA MULATTA; RETINA; RETINAL GANGLION CELLS; SODIUM CHANNEL BLOCKERS; TETRODOTOXIN; VISUAL PATHWAYS;

EID: 80055111395     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.11-8376     Document Type: Article

References (55)

1. Bach M, Hoffmann MB. Update on the pattern electroretinogram in glaucoma. Optom Vis Sci. 2008;85:386-395.
2. Berardi N, Domenici L, Gravina A, Maffei L. Pattern ERG in rats following section of the optic nerve. Exp Brain Res. 1990;79:539-546.
3. Harrison JM, O'Connor PS, Young RS, Kincaid M, Bentley R. The pattern ERG in man following surgical resection of the optic nerve. Invest Ophthalmol Vis Sci. 1987;28:492-499.
4. Holder GE. Pattern electroretinography (PERG) and an integrated approach to visual pathway diagnosis. Prog Retin Eye Res. 2001; 20:531-561.
5. Johnson MA, Drum BA, Quigley HA, Sanchez RM, Dunkelberger GR. Pattern-evoked potentials and optic nerve fiber loss in monocular laser-induced glaucoma. Invest Ophthalmol Vis Sci. 1989; 30:897-907.
6. Maffei L, Fiorentini A. Electroretinographic responses to alternating gratings in the cat. Exp Brain Res. 1982;48:327-334.
7. Maffei L, Fiorentini A, Bisti S, Hollander H. Pattern ERG in the monkey after section of the optic nerve. Exp Brain Res. 1985;59: 423-425.
8. Miura G, Wang MH, Ivers KM, Frishman LJ. Retinal pathway origins of the pattern ERG of the mouse. Exp Eye Res. 2009;89:49-62.
9. Porciatti V, Pizzorusso T, Cenni MC, Maffei L. The visual response of retinal ganglion cells is not altered by optic nerve transection in transgenic mice overexpressing Bcl-2. Proc Natl Acad Sci USA. 1996;93:14955-14959.
10. Viswanathan S, Frishman LJ, Robson JG. The uniform field and pattern ERG in macaques with experimental glaucoma: removal of spiking activity. Invest Ophthalmol Vis Sci. 2000;41:2797-2810.
11. Bui BV, Fortune B, Cull G, Wang L, Cioffi GA. Baseline characteristics of the transient pattern electroretinogram in non-human primates: inter-ocular and inter-session variability. Exp Eye Res. 2003;77:555-566.
12. Aldebasi YH, Drasdo N, Morgan JE, North RV. S-cone, L _ M-cone, and pattern electroretinograms in ocular hypertension and glaucoma. Vision Res. 2004;44:2749-2756.
13. Arai M, Yoshimura N, Sakaue H, Chihara E, Honda Y. A 3-year follow-up study of ocular hypertension by pattern electroretinogram. Ophthalmologica. 1993;207:187-195.
14. Bach M, Hiss P, Rover J. Check-size specific changes of pattern electroretinogram in patients with early open-angle glaucoma. Doc Ophthalmol. 1988;69:315-322.
15. Bach M, Unsoeld AS, Philippin H, et al. Pattern ERG as an early glaucoma indicator in ocular hypertension: a long-term, prospective study. Invest Ophthalmol Vis Sci. 2006;47:4881-4887.
16. Hood DC, Xu L, Thienprasiddhi P, et al. The pattern electroretinogram in glaucoma patients with confirmed visual field deficits. Invest Ophthalmol Vis Sci. 2005;46:2411-2418.
17. Pfeiffer N, Tillmon B, Bach M. Predictive value of the pattern electroretinogram in high-risk ocular hypertension. Invest Ophthalmol Vis Sci. 1993;34:1710-1715.
18. Ventura LM, Porciatti V, Ishida K, Feuer WJ, Parrish RK 2nd. Pattern electroretinogram abnormality and glaucoma. Ophthalmology. 2005;112:10-19.
19. Ventura LM, Sorokac N, De Los Santos R, Feuer WJ, Porciatti V. The relationship between retinal ganglion cell function and retinal nerve fiber thickness in early glaucoma. Invest Ophthalmol Vis Sci. 2006;47:3904-3911.
20. Viswanathan S, Frishman LJ, Robson JG, Harwerth RS, Smith EL 3rd. The photopic negative response of the macaque electroretinogram: reduction by experimental glaucoma. Invest Ophthalmol Vis Sci. 1999;40:1124-1136.
21. Luo X, Patel NB, Harwerth RS, Frishman LJ. Loss of the lowfrequency component of the global-flash multifocal electroretinogram in primate eyes with experimental glaucoma. Invest Ophthalmol Vis Sci. 2011;52:3792-3804.
22. Sieving PA, Murayama K, Naarendorp F. Push-pull model of the primate photopic electroretinogram: a role for hyperpolarizing neurons in shaping the b-wave. Vis Neurosci. 1994;11:519-532.
23. Slaughter MM, Miller RF. 2-Amino-4-phosphonobutyric acid: a new pharmacological tool for retina research. Science. 1981;211:182-185.
24. Slaughter MM, Miller RF. Bipolar cells in the mudpuppy retina use an excitatory amino acid neurotransmitter. Nature. 1983;303:537-538.
25. Slaughter MM, Miller RF. The role of excitatory amino acid transmitters in the mudpuppy retina: an analysis with kainic acid and N-methyl aspartate. J Neurosci. 1983;3:1701-1711.
26. Hille B. Common mode of action of three agents that decrease the transient change in sodium permeability in nerves. Nature. 1966; 210:1220-1222.
27. Harwerth RS, Smith EL 3rd, DeSantis L. Experimental glaucoma: perimetric field defects and intraocular pressure. J Glaucoma. 1997;6:390-401.
28. Quigley HA, Hohman RM. Laser energy levels for trabecular meshwork damage in the primate eye. Invest Ophthalmol Vis Sci. 1983;24:1305-1307.
29. Dawson WW, Trick GL, Litzkow CA. Improved electrode for electroretinography. Invest Ophthalmol Vis Sci. 1979;18:988-991.
30. Rangaswamy NV, Shirato S, Kaneko M, Digby BI, Robson JG, Frishman LJ. Effects of spectral characteristics of Ganzfeld stimuli on the photopic negative response (PhNR) of the ERG. Invest Ophthalmol Vis Sci. 2007;48:4818-4828.
31. Viswanathan S, Frishman LJ, Robson JG. Inner-retinal contributions to the photopic sinusoidal flicker electroretinogram of macaques. Macaque photopic sinusoidal flicker ERG. Doc Ophthalmol. 2002; 105:223-242.
32. Holder GE, Brigell MG, Hawlina M, Meigen T, Vaegan, Bach M. ISCEV standard for clinical pattern electroretinography-2007 update. Doc Ophthalmol. 2007;114:111-116.
33. Hood DC, Frishman LJ, Viswanathan S, Robson JG, Ahmed J. Evidence for a ganglion cell contribution to the primate electroretinogram (ERG): effects of TTX on the multifocal ERG in macaque. Vis Neurosci. 1999;16:411-416.
34. Bach M, Holder GE. Check size tuning of the pattern electroretingoram: a reappraisal. Doc Ophthalmol. 1996;92:193-202.
35. Viswanathan S, Frishman LJ, Robson JG, Walters JW. The photopic negative response of the flash electroretinogram in primary open angle glaucoma. Invest Ophthalmol Vis Sci. 2001;42:514-522.
36. Kondo M, Ueno S, Piao CH, Miyake Y, Terasaki H. Comparison of focal macular cone ERGs in complete-type congenital stationary night blindness and APB-treated monkeys. Vision Res. 2008;48: 273-280.
37. Bush RA, Sieving PA. A proximal retinal component in the primate photopic ERG a-wave. Invest Ophthalmol Vis Sci. 1994;35:635-645.
38. Simpson MC, Viswanathan S. Comparison of uniform field and pattern electroretinograms of humans. J Modern Optics. 2007;54: 1281-1288.
39. Holden AL, Vaegan. Comparison of the focal electroretinogram and the pattern electroretinogram in the pigeon. J Physiol. 1983; 344:11-23.
40. Porciatti V, Saleh M, Nagaraju M. The pattern electroretinogram as a tool to monitor progressive retinal ganglion cell dysfunction in the DBA/2J mouse model of glaucoma. Invest Ophthalmol Vis Sci. 2007;48:745-751.
41. Raz-Prag D, Grimes WN, Fariss RN, et al. Probing potassium channel function in vivo by intracellular delivery of antibodies in a rat model of retinal neurodegeneration. Proc Natl Acad Sci USA. 2010;107:12710-12715.
42. Thompson DA, Feather S, Stanescu HC, et al. Altered electroretinograms in patients with KCNJ10 mutations and EAST syndrome. J Physiol. 2011;589:1681-1689.
43. Shirato S, Maeda H, Miura G, Frishman LJ. Postreceptoral contributions to the light-adapted ERG of mice lacking b-waves. Exp Eye Res. 2008;86:914-928.
44. Colotto A, Falsini B, Salgarello T, Iarossi G, Galan ME, Scullica L. Photopic negative response of the human ERG: losses associated with glaucomatous damage. Invest Ophthalmol Vis Sci. 2000;41: 2205-2211.
45. Holder GE, Votruba M, Carter AC, Bhattacharya SS, Fitzke FW, Moore AT. Electrophysiological findings in dominant optic atrophy (DOA) linking to the OPA1 locus on chromosome 3q 28-qter. Doc Ophthalmol. 1998;95:217-228.
46. Stafford DK, Dacey DM. Physiology of the A1 amacrine: a spiking, axon-bearing interneuron of the macaque monkey retina. Vis Neurosci. 1997;14:507-522.
47. + channels in the rat retina. Vis Neurosci. 2008;25:635-645.
48. Dhingra NK, Freed MA, Smith RG. Voltage-gated sodium channels improve contrast sensitivity of a retinal ganglion cell. J Neurosci. 2005;25:8097-8103.
49. Ichinose T, Lukasiewicz PD. Ambient light regulates sodium channel activity to dynamically control retinal signaling. J Neurosci. 2007;27:4756-4764.
50. Ichinose T, Shields CR, Lukasiewicz PD. Sodium channels in transient retinal bipolar cells enhance visual responses in ganglion cells. J Neurosci. 2005;25:1856-1865.
51. Mojumder DK, Frishman LJ, Otteson DC, Sherry DM. Voltage-gated sodium channel alpha-subunits Na(v)1.1, Na(v)1.2, and Na(v)1.6 in the distal mammalian retina. Mol Vis. 2007;13:2163-2182.
52. Mojumder DK, Sherry DM, Frishman LJ. Contribution of voltagegated sodium channels to the b-wave of the mammalian flash electroretinogram. J Physiol. 2008;586:2551-2580.
53. Pan ZH, Hu HJ. Voltage-dependent Na(_) currents in mammalian retinal cone bipolar cells. J Neurophysiol. 2000;84:2564-2571.
54. Popova E, Kupenova P. Contribution of voltage-gated sodium channels to b-and d-waves of frog electroretinogram under different conditions of light adaptation. Vision Res. 2010;50:88-98.
55. Maddox DM, Vessey KA, Yarbrough GL, et al. Allelic variance between GRM6 mutants, Grm6nob3 and Grm6nob4 results in differences in retinal ganglion cell visual responses. J Physiol. 2008;586:4409-4424.