The interaction of the Atm genotype with inflammation and oxidative stress

PLoS ONE

Volumn 9, Issue 1, 2014, Pages

  Yang, Yan ^a   Hui, Chin Wai ^b   Li, Jiali ^c   Herrup, Karl ^b,c  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Hong Kong)

^c RUTGERS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ATM PROTEIN; CASPASE 3; CYCLIN A; CYCLIN B; CYCLINE; HISTONE DEACETYLASE 4; HISTONE H2AX; HDAC5 PROTEIN, MOUSE; HISTONE DEACETYLASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATAXIA TELANGIECTASIA; ATM GENE; CELL COUNT; CELL CYCLE REGULATION; CELL LEVEL; CELL NUCLEUS; CELL STRESS; CONTROLLED STUDY; DNA REPLICATION; ENZYME ACTIVATION; EPIGENETICS; FEMALE; GENE INTERACTION; GENOTYPE; GENOTYPE ENVIRONMENT INTERACTION; HYPOXIA; INFLAMMATION; MALE; MOUSE; NERVE CELL NECROSIS; NICK END LABELING; NONHUMAN; OXIDATIVE STRESS; PHENOTYPE; PROTEIN DEFICIENCY; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PURKINJE CELL; ANIMAL; ANOXIA; GENETICS; KNOCKOUT MOUSE; METABOLISM; NERVE CELL;

ANIMALS; ANOXIA; ATAXIA TELANGIECTASIA MUTATED PROTEINS; CASPASE 3; CYCLIN A; CYCLIN B; GENOTYPE; HISTONE DEACETYLASES; INFLAMMATION; MICE; MICE, KNOCKOUT; NEURONS; OXIDATIVE STRESS; PROLIFERATING CELL NUCLEAR ANTIGEN; PURKINJE CELLS;

EID: 84919348850     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0085863     Document Type: Article

References (42)

1. Crawford TO (1998) Ataxia telangiectasia. Semin Pediatr Neurol 5: 287-294.
2. Kastan MB, Lim DS (2000) The many substrates and functions of ATM. Nat Rev Mol Cell Biol 1: 179-186.
3. Li J, Han YR, Plummer MR, Herrup K (2009) Cytoplasmic ATM in neurons modulates synaptic function. Curr Biol 19: 2091-2096.
4. Yang DQ, Kastan MB (2000) Participation of ATM in insulin signalling through phosphorylation of eIF-4E-binding protein 1. Nat Cell Biol 2: 893-898.
5. Miles PD, Treuner K, Latronica M, Olefsky JM, Barlow C (2007) Impaired insulin secretion in a mouse model of ataxia telangiectasia. Am J Physiol Endocrinol Metab 293: E70-74. (Pubitemid 47105918)
6. Li J, Chen J, Ricupero CL, Hart RP, Schwartz MS, et al. (2012) Nuclear accumulation of HDAC4 in ATM deficiency promotes neurodegeneration in ataxia telangiectasia. Nature medicine 18: 783-790.
7. Valentin-Vega YA, Maclean KH, Tait-Mulder J, Milasta S, Steeves M, et al. (2012) Mitochondrial dysfunction in ataxia-telangiectasia. Blood 119: 1490-1500.
8. Schneider JG, Finck BN, Ren J, Standley KN, Takagi M, et al. (2006) ATM-dependent suppression of stress signaling reduces vascular disease in metabolic syndrome. Cell Metab 4: 377-389. (Pubitemid 44645067)
9. Chen P, Peng C, Luff J, Spring K, Watters D, et al. (2003) Oxidative stress is responsible for deficient survival and dendritogenesis in purkinje neurons from ataxia-telangiectasia mutated mutant mice. J Neurosci 23: 11453-11460. (Pubitemid 37549702)
10. Kruman, II, Wersto RP, Cardozo-Pelaez F, Smilenov L, Chan SL, et al. (2004) Cell cycle activation linked to neuronal cell death initiated by DNA damage. Neuron 41: 549-561. (Pubitemid 38253067)
11. Herrup K, Li J, Chen J (2013) The role of ATM and DNA damage in neurons: Upstream and downstream connections. DNA Repair (Amst) 12: 600-604.
12. Yang Y, Herrup K (2005) Loss of neuronal cell cycle control in ataxia-telangiectasia: a unified disease mechanism. J Neurosci 25: 2522-2529. (Pubitemid 40365163)
13. Li J, Chen J, Vinters HV, Gatti RA, Herrup K (2011) Stable brain ATM message and residual kinase-active ATM protein in ataxia-telangiectasia. J Neurosci 31: 7568-7577.
14. Yang Y, Herrup K (2007) Cell division in the CNS: protective response or lethal event in post-mitotic neurons? Biochim Biophys Acta 1772: 457-466. (Pubitemid 46420409)
15. Zhu XW, Lee HG, Perry G, Smith MA (2007) Alzheimer disease, the two-hit hypothesis: An update. Biochimica Et Biophysica Acta-Molecular Basis of Disease 1772: 494-502. (Pubitemid 46400383)
16. Guo Z, Deshpande R, Paull TT (2010) ATM activation in the presence of oxidative stress. Cell Cycle 9: 4805-4811.
17. Guo Z, Kozlov S, Lavin MF, Person MD, Paull TT (2010) ATM activation by oxidative stress. Science 330: 517-521.
18. Cunningham C (2013) Microglia and Neurodegeneration: The Role of Systemic Inflammation. Glia 61: 70-90.
19. Akiyama H, Barger S, Barnum S, Bradt B, Bauer J, et al. (2000) Inflammation and Alzheimer's disease. Neurobiol Aging 21: 383-421. (Pubitemid 30349107)
20. Hoozemans JJ, Bruckner MK, Rozemuller AJ, Veerhuis R, Eikelenboom P, et al. (2002) Cyclin D1 and cyclin E are co-localized with cyclo-oxygenase 2 (COX-2) in pyramidal neurons in Alzheimer disease temporal cortex. J Neuropathol Exp Neurol 61: 678-688. (Pubitemid 34851771)
21. Mackenzie IR (2001) Postmortem studies of the effect of anti-inflammatory drugs on Alzheimer-type pathology and associated inflammation. Neurobiol Aging 22: 819-822.
22. McGeer P, Kawamata T, Walker D, Akiyama H, Tooyama I, et al. (1993) Microglia in degenerative neurological disease. Glia 7: 84-92.
23. Barlow C, Ribaut-Barassin C, Zwingman TA, Pope AJ, Brown KD, et al. (2000) ATM is a cytoplasmic protein in mouse brain required to prevent lysosomal accumulation. Proc Natl Acad Sci U S A 97: 871-876. (Pubitemid 30070402)
24. Kuljis RO, Chen G, Lee EY, Aguila MC, Xu Y (1999) ATM immunolocalization in mouse neuronal endosomes: implications for ataxia-telangiectasia. Brain Res 842: 351-358. (Pubitemid 29475169)
25. Eilam R, Peter Y, Groner Y, Segal M (2003) Late degeneration of nigro-striatal neurons in ATM-/- mice. Neuroscience 121: 83-98. (Pubitemid 37297616)
26. Herrup K, Yang Y (2007) Cell cycle regulation in the postmitotic neuron: oxymoron or new biology? Nat Rev Neurosci 8: 368-378. (Pubitemid 46652467)
27. Knudson AG, Jr. (1971) Mutation and cancer: statistical study of retinoblastoma. Proc Natl Acad Sci U S A 68: 820-823.
28. Wetzel MK, Naska S, Laliberte CL, Rymar VV, Fujitani M, et al. (2008) p73 regulates neurodegeneration and phospho-tau accumulation during aging and Alzheimer's disease. Neuron 59: 708-721.
29. Raetz CR, Whitfield C (2002) Lipopolysaccharide endotoxins. Annu Rev Biochem 71: 635-700. (Pubitemid 34800232)
30. Gayle DA, Beloosesky R, Desai M, Amidi F, Nunez SE, et al. (2004) Maternal LPS induces cytokines in the amniotic fluid and corticotropin releasing hormone in the fetal rat brain. Am J Physiol Regul Integr Comp Physiol 286: R1024-1029. (Pubitemid 38661389)
31. Shaw KN, Commins S, O'Mara SM (2001) Lipopolysaccharide causes deficits in spatial learning in the watermaze but not in BDNF expression in the rat dentate gyrus. Behav Brain Res 124: 47-54. (Pubitemid 32567558)
32. Jones TB, McDaniel EE, Popovich PG (2005) Inflammatory-mediated injury and repair in the traumatically injured spinal cord. Curr Pharm Des 11: 1223-1236. (Pubitemid 40458268)
33. Combrinck MI, Perry VH, Cunningham C (2002) Peripheral infection evokes exaggerated sickness behaviour in pre-clinical murine prion disease. Neuroscience 112: 7-11. (Pubitemid 34603493)
34. Sly LM, Krzesicki RF, Brashler JR, Buhl AE, McKinley DD, et al. (2001) Endogenous brain cytokine mRNA and inflammatory responses to lipopolysaccharide are elevated in the Tg2576 transgenic mouse model of Alzheimer's disease. Brain Res Bull 56: 581-588. (Pubitemid 34098810)
35. Lee J, Chan SL, Mattson MP (2002) Adverse effect of a presenilin-1 mutation in microglia results in enhanced nitric oxide and inflammatory cytokine responses to immune challenge in the brain. Neuromolecular Med 2: 29-45. (Pubitemid 37012508)
36. Kitazawa M, Oddo S, Yamasaki TR, Green KN, LaFerla FM (2005) Lipopolysaccharide-induced inflammation exacerbates tau pathology by a cyclin-dependent kinase 5-mediated pathway in a transgenic model of Alzheimer's disease. J Neurosci 25: 8843-8853. (Pubitemid 41384452)
37. Yamasaki Y, Matsuura N, Shozuhara H, Onodera H, Itoyama Y, et al. (1995) Interleukin-1 as a pathogenetic mediator of ischemic brain damage in rats. Stroke 26: 676-680; discussion 681.
38. Stroemer RP, Rothwell NJ (1998) Exacerbation of ischemic brain damage by localized striatal injection of interleukin-1beta in the rat. J Cereb Blood Flow Metab 18: 833-839.
39. Laye S, Parnet P, Goujon E, Dantzer R (1994) Peripheral administration of lipopolysaccharide induces the expression of cytokine transcripts in the brain and pituitary of mice. Brain Res Mol Brain Res 27: 157-162. (Pubitemid 24324102)
40. Pitossi F, del Rey A, Kabiersch A, Besedovsky H (1997) Induction of cytokine transcripts in the central nervous system and pituitary following peripheral administration of endotoxin to mice. J Neurosci Res 48: 287-298. (Pubitemid 27232703)
41. Perry VH, Newman TA, Cunningham C (2003) The impact of systemic infection on the progression of neurodegenerative disease. Nat Rev Neurosci 4: 103-112. (Pubitemid 37271380)
42. Barlow C, Hirotsune S, Paylor R, Liyanage M, Eckhaus M, et al. (1996) Atm-deficient mice: a paradigm of ataxia telangiectasia. Cell 86: 159-171. (Pubitemid 26259926)