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Volumn 16, Issue 12, 2014, Pages 985-990

Recognition of Legionella pneumophila nucleic acids by innate immune receptors

Author keywords

Innate immune receptors; Legionella; Nucleic acid sensing

Indexed keywords

BACTERIAL DNA; BACTERIAL PROTEIN; INFLAMMASOME; INTERFERON; INTERFERON REGULATORY FACTOR 3; NUCLEIC ACID; TOLL LIKE RECEPTOR 9; IMMUNOGLOBULIN RECEPTOR; TOLL LIKE RECEPTOR;

EID: 84918831594     PISSN: 12864579     EISSN: 1769714X     Source Type: Journal    
DOI: 10.1016/j.micinf.2014.08.008     Document Type: Article
Times cited : (8)

References (73)
  • 2
    • 84903450177 scopus 로고    scopus 로고
    • Free-living amoebae: what part do they play in healthcare-associated infections?
    • Cateau E., Delafont V., Hechard Y., Rodier M.H. Free-living amoebae: what part do they play in healthcare-associated infections?. J Hosp Infect 2014, 87:131-140.
    • (2014) J Hosp Infect , vol.87 , pp. 131-140
    • Cateau, E.1    Delafont, V.2    Hechard, Y.3    Rodier, M.H.4
  • 3
    • 0018885613 scopus 로고
    • Legionnaires' disease bacterium (Legionella pneumophila) multiples intracellularly in human monocytes
    • Horwitz M.A., Silverstein S.C. Legionnaires' disease bacterium (Legionella pneumophila) multiples intracellularly in human monocytes. J Clin Invest 1980, 66:441-450.
    • (1980) J Clin Invest , vol.66 , pp. 441-450
    • Horwitz, M.A.1    Silverstein, S.C.2
  • 4
    • 0021169749 scopus 로고
    • Interaction between the legionnaires' disease bacterium (Legionella pneumophila) and human alveolar macrophages. Influence of antibody, lymphokines, and hydrocortisone
    • Nash T.W., Libby D.M., Horwitz M.A. Interaction between the legionnaires' disease bacterium (Legionella pneumophila) and human alveolar macrophages. Influence of antibody, lymphokines, and hydrocortisone. J Clin Invest 1984, 74:771-782.
    • (1984) J Clin Invest , vol.74 , pp. 771-782
    • Nash, T.W.1    Libby, D.M.2    Horwitz, M.A.3
  • 5
    • 84886664140 scopus 로고    scopus 로고
    • From amoeba to macrophages: exploring the molecular mechanisms of Legionella pneumophila infection in both hosts
    • Escoll P., Rolando M., Gomez-Valero L., Buchrieser C. From amoeba to macrophages: exploring the molecular mechanisms of Legionella pneumophila infection in both hosts. Curr Top Microbiol Immunol 2013, 376:1-34.
    • (2013) Curr Top Microbiol Immunol , vol.376 , pp. 1-34
    • Escoll, P.1    Rolando, M.2    Gomez-Valero, L.3    Buchrieser, C.4
  • 6
    • 78049370513 scopus 로고    scopus 로고
    • Modulation of host cell function by Legionella pneumophila type IV effectors
    • Hubber A., Roy C.R. Modulation of host cell function by Legionella pneumophila type IV effectors. Annu Rev Cell Dev Biol 2010, 26:261-283.
    • (2010) Annu Rev Cell Dev Biol , vol.26 , pp. 261-283
    • Hubber, A.1    Roy, C.R.2
  • 7
    • 81355138899 scopus 로고    scopus 로고
    • Manipulation of host vesicular trafficking and innate immune defence by Legionella Dot/Icm effectors
    • Ge J., Shao F. Manipulation of host vesicular trafficking and innate immune defence by Legionella Dot/Icm effectors. Cell Microbiol 2011, 13:1870-1880.
    • (2011) Cell Microbiol , vol.13 , pp. 1870-1880
    • Ge, J.1    Shao, F.2
  • 8
    • 0026738809 scopus 로고
    • Identification of a Legionella pneumophila locus required for intracellular multiplication in human macrophages
    • Marra A., Blander S.J., Horwitz M.A., Shuman H.A. Identification of a Legionella pneumophila locus required for intracellular multiplication in human macrophages. Proc Natl Acad Sci U S A 1992, 89:9607-9611.
    • (1992) Proc Natl Acad Sci U S A , vol.89 , pp. 9607-9611
    • Marra, A.1    Blander, S.J.2    Horwitz, M.A.3    Shuman, H.A.4
  • 9
    • 0027472133 scopus 로고
    • Two distinct defects in intracellular growth complemented by a single genetic locus in Legionella pneumophila
    • Berger K.H., Isberg R.R. Two distinct defects in intracellular growth complemented by a single genetic locus in Legionella pneumophila. Mol Microbiol 1993, 7:7-19.
    • (1993) Mol Microbiol , vol.7 , pp. 7-19
    • Berger, K.H.1    Isberg, R.R.2
  • 10
    • 83755222623 scopus 로고    scopus 로고
    • Innate immunity to legionella pneumophila
    • Massis L.M., Zamboni D.S. Innate immunity to legionella pneumophila. Front Microbiol 2011, 2:109.
    • (2011) Front Microbiol , vol.2 , pp. 109
    • Massis, L.M.1    Zamboni, D.S.2
  • 11
    • 0029004042 scopus 로고
    • Lgn1, a gene that determines susceptibility to Legionella pneumophila, maps to mouse chromosome 13
    • Dietrich W.F., Damron D.M., Isberg R.R., Lander E.S., Swanson M.S. Lgn1, a gene that determines susceptibility to Legionella pneumophila, maps to mouse chromosome 13. Genomics 1995, 26:443-450.
    • (1995) Genomics , vol.26 , pp. 443-450
    • Dietrich, W.F.1    Damron, D.M.2    Isberg, R.R.3    Lander, E.S.4    Swanson, M.S.5
  • 12
  • 13
    • 0037228017 scopus 로고    scopus 로고
    • Birc1e is the gene within the Lgn1 locus associated with resistance to Legionella pneumophila
    • Diez E., Lee S.H., Gauthier S., Yaraghi Z., Tremblay M., Vidal S., et al. Birc1e is the gene within the Lgn1 locus associated with resistance to Legionella pneumophila. Nat Genet 2003, 33:55-60.
    • (2003) Nat Genet , vol.33 , pp. 55-60
    • Diez, E.1    Lee, S.H.2    Gauthier, S.3    Yaraghi, Z.4    Tremblay, M.5    Vidal, S.6
  • 15
    • 52549099416 scopus 로고    scopus 로고
    • Critical function for Naip5 in inflammasome activation by a conserved carboxy-terminal domain of flagellin
    • Lightfield K.L., Persson J., Brubaker S.W., Witte C.E., von Moltke J., Dunipace E.A., et al. Critical function for Naip5 in inflammasome activation by a conserved carboxy-terminal domain of flagellin. Nat Immunol 2008, 9:1171-1178.
    • (2008) Nat Immunol , vol.9 , pp. 1171-1178
    • Lightfield, K.L.1    Persson, J.2    Brubaker, S.W.3    Witte, C.E.4    von Moltke, J.5    Dunipace, E.A.6
  • 16
    • 80053379974 scopus 로고    scopus 로고
    • Innate immune recognition of bacterial ligands by NAIPs determines inflammasome specificity
    • Kofoed E.M., Vance R.E. Innate immune recognition of bacterial ligands by NAIPs determines inflammasome specificity. Nature 2011, 477:592-595.
    • (2011) Nature , vol.477 , pp. 592-595
    • Kofoed, E.M.1    Vance, R.E.2
  • 17
    • 80053349020 scopus 로고    scopus 로고
    • The NLRC4 inflammasome receptors for bacterial flagellin and type III secretion apparatus
    • Zhao Y., Yang J., Shi J., Gong Y.N., Lu Q., Xu H., et al. The NLRC4 inflammasome receptors for bacterial flagellin and type III secretion apparatus. Nature 2011, 477:596-600.
    • (2011) Nature , vol.477 , pp. 596-600
    • Zhao, Y.1    Yang, J.2    Shi, J.3    Gong, Y.N.4    Lu, Q.5    Xu, H.6
  • 18
    • 33645770203 scopus 로고    scopus 로고
    • The Birc1e cytosolic pattern-recognition receptor contributes to the detection and control of Legionella pneumophila infection
    • Zamboni D.S., Kobayashi K.S., Kohlsdorf T., Ogura Y., Long E.M., Vance R.E., et al. The Birc1e cytosolic pattern-recognition receptor contributes to the detection and control of Legionella pneumophila infection. Nat Immunol 2006, 7:318-325.
    • (2006) Nat Immunol , vol.7 , pp. 318-325
    • Zamboni, D.S.1    Kobayashi, K.S.2    Kohlsdorf, T.3    Ogura, Y.4    Long, E.M.5    Vance, R.E.6
  • 19
    • 33645791082 scopus 로고    scopus 로고
    • Flagellin-deficient Legionella mutants evade caspase-1- and Naip5-mediated macrophage immunity
    • Ren T., Zamboni D.S., Roy C.R., Dietrich W.F., Vance R.E. Flagellin-deficient Legionella mutants evade caspase-1- and Naip5-mediated macrophage immunity. PLoS Pathog 2006, 2:e18.
    • (2006) PLoS Pathog , vol.2
    • Ren, T.1    Zamboni, D.S.2    Roy, C.R.3    Dietrich, W.F.4    Vance, R.E.5
  • 20
    • 33645843633 scopus 로고    scopus 로고
    • Cytosolic recognition of flagellin by mouse macrophages restricts Legionella pneumophila infection
    • Molofsky A.B., Byrne B.G., Whitfield N.N., Madigan C.A., Fuse E.T., Tateda K., et al. Cytosolic recognition of flagellin by mouse macrophages restricts Legionella pneumophila infection. J Exp Med 2006, 203:1093-1104.
    • (2006) J Exp Med , vol.203 , pp. 1093-1104
    • Molofsky, A.B.1    Byrne, B.G.2    Whitfield, N.N.3    Madigan, C.A.4    Fuse, E.T.5    Tateda, K.6
  • 21
    • 33846024748 scopus 로고    scopus 로고
    • Regulation of Legionella phagosome maturation and infection through flagellin and host Ipaf
    • Amer A., Franchi L., Kanneganti T.D., Body-Malapel M., Ozoren N., Brady G., et al. Regulation of Legionella phagosome maturation and infection through flagellin and host Ipaf. J Biol Chem 2006, 281:35217-35223.
    • (2006) J Biol Chem , vol.281 , pp. 35217-35223
    • Amer, A.1    Franchi, L.2    Kanneganti, T.D.3    Body-Malapel, M.4    Ozoren, N.5    Brady, G.6
  • 22
    • 83755183815 scopus 로고    scopus 로고
    • Activation of NLRC4 by flagellated bacteria triggers caspase-1-dependent and -independent responses to restrict Legionella pneumophila replication in macrophages and invivo
    • Pereira M.S., Morgantetti G.F., Massis L.M., Horta C.V., Hori J.I., Zamboni D.S. Activation of NLRC4 by flagellated bacteria triggers caspase-1-dependent and -independent responses to restrict Legionella pneumophila replication in macrophages and invivo. J Immunol 2011, 187:6447-6455.
    • (2011) J Immunol , vol.187 , pp. 6447-6455
    • Pereira, M.S.1    Morgantetti, G.F.2    Massis, L.M.3    Horta, C.V.4    Hori, J.I.5    Zamboni, D.S.6
  • 23
    • 33646493350 scopus 로고    scopus 로고
    • MyD88-dependent IFN-gamma production by NK cells is key for control of Legionella pneumophila infection
    • Sporri R., Joller N., Albers U., Hilbi H., Oxenius A. MyD88-dependent IFN-gamma production by NK cells is key for control of Legionella pneumophila infection. J Immunol 2006, 176:6162-6171.
    • (2006) J Immunol , vol.176 , pp. 6162-6171
    • Sporri, R.1    Joller, N.2    Albers, U.3    Hilbi, H.4    Oxenius, A.5
  • 24
    • 33646948879 scopus 로고    scopus 로고
    • MyD88-dependent responses involving toll-like receptor 2 are important for protection and clearance of Legionella pneumophila in a mouse model of Legionnaires' disease
    • Archer K.A., Roy C.R. MyD88-dependent responses involving toll-like receptor 2 are important for protection and clearance of Legionella pneumophila in a mouse model of Legionnaires' disease. Infect Immun 2006, 74:3325-3333.
    • (2006) Infect Immun , vol.74 , pp. 3325-3333
    • Archer, K.A.1    Roy, C.R.2
  • 25
    • 33744782563 scopus 로고    scopus 로고
    • Myeloid differentiation primary response gene (88)- and toll-like receptor 2-deficient mice are susceptible to infection with aerosolized Legionella pneumophila
    • Hawn T.R., Smith K.D., Aderem A., Skerrett S.J. Myeloid differentiation primary response gene (88)- and toll-like receptor 2-deficient mice are susceptible to infection with aerosolized Legionella pneumophila. J Infect Dis 2006, 193:1693-1702.
    • (2006) J Infect Dis , vol.193 , pp. 1693-1702
    • Hawn, T.R.1    Smith, K.D.2    Aderem, A.3    Skerrett, S.J.4
  • 26
    • 77957752777 scopus 로고    scopus 로고
    • The pattern recognition receptors Nod1 and Nod2 account for neutrophil recruitment to the lungs of mice infected with Legionella pneumophila
    • Frutuoso M.S., Hori J.I., Pereira M.S., Junior D.S., Sonego F., Kobayashi K.S., et al. The pattern recognition receptors Nod1 and Nod2 account for neutrophil recruitment to the lungs of mice infected with Legionella pneumophila. Microbes infection/Institut Pasteur 2010, 12:819-827.
    • (2010) Microbes infection/Institut Pasteur , vol.12 , pp. 819-827
    • Frutuoso, M.S.1    Hori, J.I.2    Pereira, M.S.3    Junior, D.S.4    Sonego, F.5    Kobayashi, K.S.6
  • 27
    • 80054122543 scopus 로고    scopus 로고
    • Dissection of a type I interferon pathway in controlling bacterial intracellular infection in mice
    • Lippmann J., Muller H.C., Naujoks J., Tabeling C., Shin S., Witzenrath M., et al. Dissection of a type I interferon pathway in controlling bacterial intracellular infection in mice. Cell Microbiol 2011, 13:1668-1682.
    • (2011) Cell Microbiol , vol.13 , pp. 1668-1682
    • Lippmann, J.1    Muller, H.C.2    Naujoks, J.3    Tabeling, C.4    Shin, S.5    Witzenrath, M.6
  • 28
    • 3142705098 scopus 로고    scopus 로고
    • Type I IFN protects permissive macrophages from Legionella pneumophila infection through an IFN-gamma-independent pathway
    • Schiavoni G., Mauri C., Carlei D., Belardelli F., Pastoris M.C., Proietti E. Type I IFN protects permissive macrophages from Legionella pneumophila infection through an IFN-gamma-independent pathway. J Immunol 2004, 173:1266-1275.
    • (2004) J Immunol , vol.173 , pp. 1266-1275
    • Schiavoni, G.1    Mauri, C.2    Carlei, D.3    Belardelli, F.4    Pastoris, M.C.5    Proietti, E.6
  • 29
    • 34548406570 scopus 로고    scopus 로고
    • Restriction of Legionella pneumophila growth in macrophages requires the concerted action of cytokine and Naip5/Ipaf signalling pathways
    • Coers J., Vance R.E., Fontana M.F., Dietrich W.F. Restriction of Legionella pneumophila growth in macrophages requires the concerted action of cytokine and Naip5/Ipaf signalling pathways. Cell Microbiol 2007, 9:2344-2357.
    • (2007) Cell Microbiol , vol.9 , pp. 2344-2357
    • Coers, J.1    Vance, R.E.2    Fontana, M.F.3    Dietrich, W.F.4
  • 30
    • 84873202976 scopus 로고    scopus 로고
    • Caspase-11 stimulates rapid flagellin-independent pyroptosis in response to Legionella pneumophila
    • Case C.L., Kohler L.J., Lima J.B., Strowig T., de Zoete M.R., Flavell R.A., et al. Caspase-11 stimulates rapid flagellin-independent pyroptosis in response to Legionella pneumophila. Proc Natl Acad Sci U S A 2013, 110:1851-1856.
    • (2013) Proc Natl Acad Sci U S A , vol.110 , pp. 1851-1856
    • Case, C.L.1    Kohler, L.J.2    Lima, J.B.3    Strowig, T.4    de Zoete, M.R.5    Flavell, R.A.6
  • 31
    • 32944462834 scopus 로고    scopus 로고
    • Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3
    • Kanneganti T.D., Ozoren N., Body-Malapel M., Amer A., Park J.H., Franchi L., et al. Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3. Nature 2006, 440:233-236.
    • (2006) Nature , vol.440 , pp. 233-236
    • Kanneganti, T.D.1    Ozoren, N.2    Body-Malapel, M.3    Amer, A.4    Park, J.H.5    Franchi, L.6
  • 32
    • 0037439663 scopus 로고    scopus 로고
    • Lipopolysaccharides from Legionella and Rhizobium stimulate mouse bone marrow granulocytes via Toll-like receptor 2
    • Girard R., Pedron T., Uematsu S., Balloy V., Chignard M., Akira S., et al. Lipopolysaccharides from Legionella and Rhizobium stimulate mouse bone marrow granulocytes via Toll-like receptor 2. J Cell Sci 2003, 116:293-302.
    • (2003) J Cell Sci , vol.116 , pp. 293-302
    • Girard, R.1    Pedron, T.2    Uematsu, S.3    Balloy, V.4    Chignard, M.5    Akira, S.6
  • 33
    • 11144338200 scopus 로고    scopus 로고
    • Differential roles of Toll-like receptors 2 and 4 in invitro responses of macrophages to Legionella pneumophila
    • Akamine M., Higa F., Arakaki N., Kawakami K., Takeda K., Akira S., et al. Differential roles of Toll-like receptors 2 and 4 in invitro responses of macrophages to Legionella pneumophila. Infect Immun 2005, 73:352-361.
    • (2005) Infect Immun , vol.73 , pp. 352-361
    • Akamine, M.1    Higa, F.2    Arakaki, N.3    Kawakami, K.4    Takeda, K.5    Akira, S.6
  • 34
    • 38449115675 scopus 로고    scopus 로고
    • Altered inflammatory responses in TLR5-deficient mice infected with Legionella pneumophila
    • Hawn T.R., Berrington W.R., Smith I.A., Uematsu S., Akira S., Aderem A., et al. Altered inflammatory responses in TLR5-deficient mice infected with Legionella pneumophila. J Immunol 2007, 179:6981-6987.
    • (2007) J Immunol , vol.179 , pp. 6981-6987
    • Hawn, T.R.1    Berrington, W.R.2    Smith, I.A.3    Uematsu, S.4    Akira, S.5    Aderem, A.6
  • 35
    • 58149295583 scopus 로고    scopus 로고
    • Multiple MyD88-dependent responses contribute to pulmonary clearance of Legionella pneumophila
    • Archer K.A., Alexopoulou L., Flavell R.A., Roy C.R. Multiple MyD88-dependent responses contribute to pulmonary clearance of Legionella pneumophila. Cell Microbiol 2009, 11:21-36.
    • (2009) Cell Microbiol , vol.11 , pp. 21-36
    • Archer, K.A.1    Alexopoulou, L.2    Flavell, R.A.3    Roy, C.R.4
  • 36
    • 84879088424 scopus 로고    scopus 로고
    • IL-1alpha signaling initiates the inflammatory response to virulent Legionella pneumophila invivo
    • Barry K.C., Fontana M.F., Portman J.L., Dugan A.S., Vance R.E. IL-1alpha signaling initiates the inflammatory response to virulent Legionella pneumophila invivo. J Immunol 2013, 190:6329-6339.
    • (2013) J Immunol , vol.190 , pp. 6329-6339
    • Barry, K.C.1    Fontana, M.F.2    Portman, J.L.3    Dugan, A.S.4    Vance, R.E.5
  • 37
    • 33846023375 scopus 로고    scopus 로고
    • Role of Toll-like receptor 9 in Legionella pneumophila-induced interleukin-12 p40 production in bone marrow-derived dendritic cells and macrophages from permissive and nonpermissive mice
    • Newton C.A., Perkins I., Widen R.H., Friedman H., Klein T.W. Role of Toll-like receptor 9 in Legionella pneumophila-induced interleukin-12 p40 production in bone marrow-derived dendritic cells and macrophages from permissive and nonpermissive mice. Infect Immun 2007, 75:146-151.
    • (2007) Infect Immun , vol.75 , pp. 146-151
    • Newton, C.A.1    Perkins, I.2    Widen, R.H.3    Friedman, H.4    Klein, T.W.5
  • 38
    • 46449125113 scopus 로고    scopus 로고
    • Toll-like receptor 9 regulates the lung macrophage phenotype and host immunity in murine pneumonia caused by Legionella pneumophila
    • Bhan U., Trujillo G., Lyn-Kew K., Newstead M.W., Zeng X., Hogaboam C.M., et al. Toll-like receptor 9 regulates the lung macrophage phenotype and host immunity in murine pneumonia caused by Legionella pneumophila. Infect Immun 2008, 76:2895-2904.
    • (2008) Infect Immun , vol.76 , pp. 2895-2904
    • Bhan, U.1    Trujillo, G.2    Lyn-Kew, K.3    Newstead, M.W.4    Zeng, X.5    Hogaboam, C.M.6
  • 39
    • 3242813113 scopus 로고    scopus 로고
    • The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses
    • Yoneyama M., Kikuchi M., Natsukawa T., Shinobu N., Imaizumi T., Miyagishi M., et al. The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses. Nat Immunol 2004, 5:730-737.
    • (2004) Nat Immunol , vol.5 , pp. 730-737
    • Yoneyama, M.1    Kikuchi, M.2    Natsukawa, T.3    Shinobu, N.4    Imaizumi, T.5    Miyagishi, M.6
  • 40
    • 57049171269 scopus 로고    scopus 로고
    • TLR-independent type I interferon induction in response to an extracellular bacterial pathogen via intracellular recognition of its DNA
    • Charrel-Dennis M., Latz E., Halmen K.A., Trieu-Cuot P., Fitzgerald K.A., Kasper D.L., et al. TLR-independent type I interferon induction in response to an extracellular bacterial pathogen via intracellular recognition of its DNA. Cell Host Microbe 2008, 4:543-554.
    • (2008) Cell Host Microbe , vol.4 , pp. 543-554
    • Charrel-Dennis, M.1    Latz, E.2    Halmen, K.A.3    Trieu-Cuot, P.4    Fitzgerald, K.A.5    Kasper, D.L.6
  • 41
    • 34249044447 scopus 로고    scopus 로고
    • Type I interferon signaling is required for activation of the inflammasome during Francisella infection
    • Henry T., Brotcke A., Weiss D.S., Thompson L.J., Monack D.M. Type I interferon signaling is required for activation of the inflammasome during Francisella infection. J Exp Med 2007, 204:987-994.
    • (2007) J Exp Med , vol.204 , pp. 987-994
    • Henry, T.1    Brotcke, A.2    Weiss, D.S.3    Thompson, L.J.4    Monack, D.M.5
  • 42
    • 34250730896 scopus 로고    scopus 로고
    • Brucella requires a functional Type IV secretion system to elicit innate immune responses in mice
    • Roux C.M., Rolan H.G., Santos R.L., Beremand P.D., Thomas T.L., Adams L.G., et al. Brucella requires a functional Type IV secretion system to elicit innate immune responses in mice. Cell Microbiol 2007, 9:1851-1869.
    • (2007) Cell Microbiol , vol.9 , pp. 1851-1869
    • Roux, C.M.1    Rolan, H.G.2    Santos, R.L.3    Beremand, P.D.4    Thomas, T.L.5    Adams, L.G.6
  • 43
    • 33847359299 scopus 로고    scopus 로고
    • The Type I IFN response to infection with Mycobacterium tuberculosis requires ESX-1-mediated secretion and contributes to pathogenesis
    • Stanley S.A., Johndrow J.E., Manzanillo P., Cox J.S. The Type I IFN response to infection with Mycobacterium tuberculosis requires ESX-1-mediated secretion and contributes to pathogenesis. J Immunol 2007, 178:3143-3152.
    • (2007) J Immunol , vol.178 , pp. 3143-3152
    • Stanley, S.A.1    Johndrow, J.E.2    Manzanillo, P.3    Cox, J.S.4
  • 44
    • 30444450839 scopus 로고    scopus 로고
    • Recognition of cytosolic DNA activates an IRF3-dependent innate immune response
    • Stetson D.B., Medzhitov R. Recognition of cytosolic DNA activates an IRF3-dependent innate immune response. Immunity 2006, 24:93-103.
    • (2006) Immunity , vol.24 , pp. 93-103
    • Stetson, D.B.1    Medzhitov, R.2
  • 45
    • 68049092912 scopus 로고    scopus 로고
    • RNA polymerase III detects cytosolic DNA and induces type I interferons through the RIG-I pathway
    • Chiu Y.H., Macmillan J.B., Chen Z.J. RNA polymerase III detects cytosolic DNA and induces type I interferons through the RIG-I pathway. Cell 2009, 138:576-591.
    • (2009) Cell , vol.138 , pp. 576-591
    • Chiu, Y.H.1    Macmillan, J.B.2    Chen, Z.J.3
  • 46
    • 70349459734 scopus 로고    scopus 로고
    • RIG-I-dependent sensing of poly(dA:dT) through the induction of an RNA polymerase III-transcribed RNA intermediate
    • Ablasser A., Bauernfeind F., Hartmann G., Latz E., Fitzgerald K.A., Hornung V. RIG-I-dependent sensing of poly(dA:dT) through the induction of an RNA polymerase III-transcribed RNA intermediate. Nat Immunol 2009, 10:1065-1072.
    • (2009) Nat Immunol , vol.10 , pp. 1065-1072
    • Ablasser, A.1    Bauernfeind, F.2    Hartmann, G.3    Latz, E.4    Fitzgerald, K.A.5    Hornung, V.6
  • 47
    • 34547143110 scopus 로고    scopus 로고
    • DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response
    • Takaoka A., Wang Z., Choi M.K., Yanai H., Negishi H., Ban T., et al. DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response. Nature 2007, 448:501-505.
    • (2007) Nature , vol.448 , pp. 501-505
    • Takaoka, A.1    Wang, Z.2    Choi, M.K.3    Yanai, H.4    Negishi, H.5    Ban, T.6
  • 48
    • 70349943834 scopus 로고    scopus 로고
    • STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity
    • Ishikawa H., Ma Z., Barber G.N. STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity. Nature 2009, 461:788-792.
    • (2009) Nature , vol.461 , pp. 788-792
    • Ishikawa, H.1    Ma, Z.2    Barber, G.N.3
  • 49
    • 84873711885 scopus 로고    scopus 로고
    • Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway
    • Sun L., Wu J., Du F., Chen X., Chen Z.J. Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway. Science 2013, 339:786-791.
    • (2013) Science , vol.339 , pp. 786-791
    • Sun, L.1    Wu, J.2    Du, F.3    Chen, X.4    Chen, Z.J.5
  • 50
    • 0032488861 scopus 로고    scopus 로고
    • Conjugative transfer by the virulence system of Legionella pneumophila
    • Vogel J.P., Andrews H.L., Wong S.K., Isberg R.R. Conjugative transfer by the virulence system of Legionella pneumophila. Science 1998, 279:873-876.
    • (1998) Science , vol.279 , pp. 873-876
    • Vogel, J.P.1    Andrews, H.L.2    Wong, S.K.3    Isberg, R.R.4
  • 51
    • 33845986012 scopus 로고    scopus 로고
    • Legionella pneumophila induces IFNbeta in lung epithelial cells via IPS-1 and IRF3, which also control bacterial replication
    • Opitz B., Vinzing M., van Laak V., Schmeck B., Heine G., Gunther S., et al. Legionella pneumophila induces IFNbeta in lung epithelial cells via IPS-1 and IRF3, which also control bacterial replication. J Biol Chem 2006, 281:36173-36179.
    • (2006) J Biol Chem , vol.281 , pp. 36173-36179
    • Opitz, B.1    Vinzing, M.2    van Laak, V.3    Schmeck, B.4    Heine, G.5    Gunther, S.6
  • 52
    • 73549090166 scopus 로고    scopus 로고
    • Identification of host cytosolic sensors and bacterial factors regulating the type I interferon response to Legionella pneumophila
    • Monroe K.M., McWhirter S.M., Vance R.E. Identification of host cytosolic sensors and bacterial factors regulating the type I interferon response to Legionella pneumophila. PLoS Pathog 2009, 5:e1000665.
    • (2009) PLoS Pathog , vol.5
    • Monroe, K.M.1    McWhirter, S.M.2    Vance, R.E.3
  • 53
    • 79961003564 scopus 로고    scopus 로고
    • MyD88 and STING signaling pathways are required for IRF3-mediated IFN-beta induction in response to Brucella abortus infection
    • de Almeida L.A., Carvalho N.B., Oliveira F.S., Lacerda T.L., Vasconcelos A.C., Nogueira L., et al. MyD88 and STING signaling pathways are required for IRF3-mediated IFN-beta induction in response to Brucella abortus infection. PloS one 2011, 6:e23135.
    • (2011) PloS one , vol.6
    • de Almeida, L.A.1    Carvalho, N.B.2    Oliveira, F.S.3    Lacerda, T.L.4    Vasconcelos, A.C.5    Nogueira, L.6
  • 54
    • 4344627833 scopus 로고    scopus 로고
    • Type I interferon production enhances susceptibility to Listeria monocytogenes infection
    • O'Connell R.M., Saha S.K., Vaidya S.A., Bruhn K.W., Miranda G.A., Zarnegar B., et al. Type I interferon production enhances susceptibility to Listeria monocytogenes infection. J Exp Med 2004, 200:437-445.
    • (2004) J Exp Med , vol.200 , pp. 437-445
    • O'Connell, R.M.1    Saha, S.K.2    Vaidya, S.A.3    Bruhn, K.W.4    Miranda, G.A.5    Zarnegar, B.6
  • 55
    • 84873724533 scopus 로고    scopus 로고
    • Cyclic GMP-AMP is an endogenous second messenger in innate immune signaling by cytosolic DNA
    • Wu J., Sun L., Chen X., Du F., Shi H., Chen C., et al. Cyclic GMP-AMP is an endogenous second messenger in innate immune signaling by cytosolic DNA. Science 2013, 339:826-830.
    • (2013) Science , vol.339 , pp. 826-830
    • Wu, J.1    Sun, L.2    Chen, X.3    Du, F.4    Shi, H.5    Chen, C.6
  • 57
    • 84878572947 scopus 로고    scopus 로고
    • The innate immune DNA sensor cGAS produces a noncanonical cyclic dinucleotide that activates human STING
    • Diner E.J., Burdette D.L., Wilson S.C., Monroe K.M., Kellenberger C.A., Hyodo M., et al. The innate immune DNA sensor cGAS produces a noncanonical cyclic dinucleotide that activates human STING. Cell Reports 2013, 3:1355-1361.
    • (2013) Cell Reports , vol.3 , pp. 1355-1361
    • Diner, E.J.1    Burdette, D.L.2    Wilson, S.C.3    Monroe, K.M.4    Kellenberger, C.A.5    Hyodo, M.6
  • 58
    • 84879385334 scopus 로고    scopus 로고
    • CGAS produces a 2'-5'-linked cyclic dinucleotide second messenger that activates STING
    • Ablasser A., Goldeck M., Cavlar T., Deimling T., Witte G., Rohl I., et al. cGAS produces a 2'-5'-linked cyclic dinucleotide second messenger that activates STING. Nature 2013, 498:380-384.
    • (2013) Nature , vol.498 , pp. 380-384
    • Ablasser, A.1    Goldeck, M.2    Cavlar, T.3    Deimling, T.4    Witte, G.5    Rohl, I.6
  • 59
    • 84905375825 scopus 로고    scopus 로고
    • Listeria monocytogenes induces IFNbeta expression through an IFI16-, cGAS- and STING-dependent pathway
    • Hansen K., Prabakaran T., Laustsen A., Jorgensen S.E., Rahbaek S.H., Jensen S.B., et al. Listeria monocytogenes induces IFNbeta expression through an IFI16-, cGAS- and STING-dependent pathway. EMBO J 2014, 33(15):1654-1666.
    • (2014) EMBO J , vol.33 , Issue.15 , pp. 1654-1666
    • Hansen, K.1    Prabakaran, T.2    Laustsen, A.3    Jorgensen, S.E.4    Rahbaek, S.H.5    Jensen, S.B.6
  • 60
    • 65449134828 scopus 로고    scopus 로고
    • Asc and Ipaf inflammasomes direct distinct pathways for caspase-1 activation in response to Legionella pneumophila
    • Case C.L., Shin S., Roy C.R. Asc and Ipaf inflammasomes direct distinct pathways for caspase-1 activation in response to Legionella pneumophila. Infect Immun 2009, 77:1981-1991.
    • (2009) Infect Immun , vol.77 , pp. 1981-1991
    • Case, C.L.1    Shin, S.2    Roy, C.R.3
  • 62
    • 60749136484 scopus 로고    scopus 로고
    • An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome
    • Burckstummer T., Baumann C., Bluml S., Dixit E., Durnberger G., Jahn H., et al. An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome. Nat Immunol 2009, 10:266-272.
    • (2009) Nat Immunol , vol.10 , pp. 266-272
    • Burckstummer, T.1    Baumann, C.2    Bluml, S.3    Dixit, E.4    Durnberger, G.5    Jahn, H.6
  • 63
    • 63649145255 scopus 로고    scopus 로고
    • AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA
    • Fernandes-Alnemri T., Yu J.W., Datta P., Wu J., Alnemri E.S. AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA. Nature 2009, 458:509-513.
    • (2009) Nature , vol.458 , pp. 509-513
    • Fernandes-Alnemri, T.1    Yu, J.W.2    Datta, P.3    Wu, J.4    Alnemri, E.S.5
  • 64
  • 65
    • 60749104535 scopus 로고    scopus 로고
    • HIN-200 proteins regulate caspase activation in response to foreign cytoplasmic DNA
    • Roberts T.L., Idris A., Dunn J.A., Kelly G.M., Burnton C.M., Hodgson S., et al. HIN-200 proteins regulate caspase activation in response to foreign cytoplasmic DNA. Science 2009, 323:1057-1060.
    • (2009) Science , vol.323 , pp. 1057-1060
    • Roberts, T.L.1    Idris, A.2    Dunn, J.A.3    Kelly, G.M.4    Burnton, C.M.5    Hodgson, S.6
  • 66
    • 83655163772 scopus 로고    scopus 로고
    • Francisella infection triggers activation of the AIM2 inflammasome in murine dendritic cells
    • Belhocine K., Monack D.M. Francisella infection triggers activation of the AIM2 inflammasome in murine dendritic cells. Cell Microbiol 2012, 14:71-80.
    • (2012) Cell Microbiol , vol.14 , pp. 71-80
    • Belhocine, K.1    Monack, D.M.2
  • 67
    • 77951263260 scopus 로고    scopus 로고
    • The AIM2 inflammasome is critical for innate immunity to Francisella tularensis
    • Fernandes-Alnemri T., Yu J.W., Juliana C., Solorzano L., Kang S., Wu J., et al. The AIM2 inflammasome is critical for innate immunity to Francisella tularensis. Nat Immunol 2010, 11:385-393.
    • (2010) Nat Immunol , vol.11 , pp. 385-393
    • Fernandes-Alnemri, T.1    Yu, J.W.2    Juliana, C.3    Solorzano, L.4    Kang, S.5    Wu, J.6
  • 68
    • 77953116282 scopus 로고    scopus 로고
    • Absent in melanoma 2 is required for innate immune recognition of Francisella tularensis
    • Jones J.W., Kayagaki N., Broz P., Henry T., Newton K., O'Rourke K., et al. Absent in melanoma 2 is required for innate immune recognition of Francisella tularensis. Proc Natl Acad Sci U S A 2010, 107:9771-9776.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 9771-9776
    • Jones, J.W.1    Kayagaki, N.2    Broz, P.3    Henry, T.4    Newton, K.5    O'Rourke, K.6
  • 69
    • 77951269392 scopus 로고    scopus 로고
    • The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses
    • Rathinam V.A., Jiang Z., Waggoner S.N., Sharma S., Cole L.E., Waggoner L., et al. The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses. Nat Immunol 2010, 11:395-402.
    • (2010) Nat Immunol , vol.11 , pp. 395-402
    • Rathinam, V.A.1    Jiang, Z.2    Waggoner, S.N.3    Sharma, S.4    Cole, L.E.5    Waggoner, L.6
  • 70
    • 77957578665 scopus 로고    scopus 로고
    • Involvement of the AIM2, NLRC4, and NLRP3 inflammasomes in caspase-1 activation by Listeria monocytogenes
    • Wu J., Fernandes-Alnemri T., Alnemri E.S. Involvement of the AIM2, NLRC4, and NLRP3 inflammasomes in caspase-1 activation by Listeria monocytogenes. J Clin Immunol 2010, 30:693-702.
    • (2010) J Clin Immunol , vol.30 , pp. 693-702
    • Wu, J.1    Fernandes-Alnemri, T.2    Alnemri, E.S.3
  • 71
    • 84857752089 scopus 로고    scopus 로고
    • The protein SdhA maintains the integrity of the Legionella-containing vacuole
    • Creasey E.A., Isberg R.R. The protein SdhA maintains the integrity of the Legionella-containing vacuole. Proc Natl Acad Sci U S A 2012, 109:3481-3486.
    • (2012) Proc Natl Acad Sci U S A , vol.109 , pp. 3481-3486
    • Creasey, E.A.1    Isberg, R.R.2
  • 72
    • 84859945146 scopus 로고    scopus 로고
    • Preventing bacterial DNA release and absent in melanoma 2 inflammasome activation by a Legionella effector functioning in membrane trafficking
    • Ge J., Gong Y.N., Xu Y., Shao F. Preventing bacterial DNA release and absent in melanoma 2 inflammasome activation by a Legionella effector functioning in membrane trafficking. Proc Natl Acad Sci U S A 2012, 109:6193-6198.
    • (2012) Proc Natl Acad Sci U S A , vol.109 , pp. 6193-6198
    • Ge, J.1    Gong, Y.N.2    Xu, Y.3    Shao, F.4
  • 73
    • 33845511552 scopus 로고    scopus 로고
    • A Legionella pneumophila-translocated substrate that is required for growth within macrophages and protection from host cell death
    • Laguna R.K., Creasey E.A., Li Z., Valtz N., Isberg R.R. A Legionella pneumophila-translocated substrate that is required for growth within macrophages and protection from host cell death. Proc Natl Acad Sci U S A 2006, 103:18745-18750.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 18745-18750
    • Laguna, R.K.1    Creasey, E.A.2    Li, Z.3    Valtz, N.4    Isberg, R.R.5


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