Gram-scale enantioselective formal synthesis of morphine through an orthöpara oxidative phenolic coupling strategy

Angewandte Chemie - International Edition

Volumn 53, Issue 49, 2014, Pages 13498-13501

  Tissot, Matthieu ^a   Phipps, Robert J ^a   Lucas, Catherine ^a   Leon, Rafael M ^a   Pace, Robert D M ^a   Ngouansavanh, Tifelle ^a   Gaunt, Matthew J ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

Alkaloids; Asymmetric synthesis; Oxidative coupling; Total synthesis

Indexed keywords

ALKALOIDS; STEREOSELECTIVITY;

ASYMMETRIC SYNTHESIS; DESYM-METRIZATION; DIASTEREOSELECTIVE; ENANTIOSELECTIVE; ENANTIOSELECTIVE HYDROGENATION; OXIDATIVE COUPLINGS; SCALABLE SYNTHESIS; TOTAL SYNTHESIS;

ENANTIOSELECTIVITY;

MORPHINE; NARCOTIC ANALGESIC AGENT; PHENOL DERIVATIVE;

CHEMISTRY; OXIDATIVE COUPLING; STEREOISOMERISM; SYNTHESIS;

ANALGESICS, OPIOID; MORPHINE; OXIDATIVE COUPLING; PHENOLS; STEREOISOMERISM;

EID: 84918779876     PISSN: 14337851     EISSN: 15213773     Source Type: Journal    
DOI: 10.1002/anie.201408435     Document Type: Article

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