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Angewandte Chemie - International Edition

Volumn 53, Issue 17, 2014, Pages 4355-4358

Short chemoenzymatic total synthesis of ent-hydromorphone: An oxidative dearomatization/intramolecular [4+2] cycloaddition/amination sequence

(2) Varghese, Vimal a Hudlicky, Tomas a

a BROCK UNIVERSITY (Canada)

Author keywords

alkaloids; cycloaddition; natural products; oxidation; total synthesis

Indexed keywords

ALKALOIDS; AMINES; CYCLOADDITION; HYDROXYLATION; OXIDATION;

DEAROMATIZATION; DIHYDROXYLATION; INTRAMOLECULAR AMINATION; NATURAL PRODUCTS; TERT-BUTYLDIMETHYLSILYL; TOTAL SYNTHESIS;

SYNTHESIS (CHEMICAL);

DIOXYGENASE; HYDROMORPHONE; NARCOTIC ANALGESIC AGENT;

AMINATION; CHEMICAL STRUCTURE; CYCLIZATION; CYCLOADDITION; METABOLISM; OXIDATION REDUCTION REACTION; STEREOISOMERISM; SYNTHESIS;

AMINATION; ANALGESICS, OPIOID; CYCLIZATION; CYCLOADDITION REACTION; DIOXYGENASES; HYDROMORPHONE; MOLECULAR STRUCTURE; OXIDATION-REDUCTION; STEREOISOMERISM;

EID: 84898930100 PISSN: 14337851 EISSN: 15213773 Source Type: Journal
DOI: 10.1002/anie.201400286 Document Type: Article

Times cited : (53)

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