Design for morphine alkaloids by intramolecular Heck strategy: Chemoenzymatic synthesis of 10-hydroxy-14-epi-dihydrocodeinone via C-D-B ring construction

Synlett

Volumn , Issue 18, 2007, Pages 2863-2867

  Zezula, Josef ^a   Rice, Kenner C ^a   Hudlicky, Tomas ^b  

^a NATIONAL INSTITUTE ON DRUG ABUSE   (United States)

^b BROCK UNIVERSITY   (Canada)

Author keywords

Enzymatic dihydroxylation; Friedel Crafts reaction; Heck reaction; Mitsunobu reaction; Morphinans

Indexed keywords

10 HYDROXY 14 EPI DIHYDROCODEINONE; ALKADIENE; BETA BROMOETHYLBENZENE; ETHYLBENZENE; HYDROCODONE; MORPHINAN DERIVATIVE; MORPHINE; UNCLASSIFIED DRUG;

ARTICLE; CYCLIZATION; DIHYDROXYLATION; ENZYME SYNTHESIS; HECK REACTION;

EID: 36549079966     PISSN: 09365214     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2007-990832     Document Type: Article

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