Parenteral lipids: Safety aspects and toxicity

World Review of Nutrition and Dietetics

Volumn 112, Issue , 2015, Pages 63-70

  Wanten, Geert J A ^a  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCINE MAX;

ANTIOXIDANT; EMULSION; ESSENTIAL FATTY ACID; FISH OIL; GLUCOSE; PHYTOSTEROL; SOYBEAN OIL;

ADVERSE EFFECTS; ANIMAL; DRUG EFFECTS; EMULSION; HUMAN; LIVER; LUNG; METABOLISM; PARENTERAL NUTRITION; TOXICITY TESTING;

ANIMALS; ANTIOXIDANTS; EMULSIONS; FATTY ACIDS, ESSENTIAL; FISH OILS; GLUCOSE; HUMANS; LIVER; LUNG; PARENTERAL NUTRITION; PHYTOSTEROLS; SOYBEAN OIL; TOXICITY TESTS;

EID: 84918776485     PISSN: 00842230     EISSN: 16623975     Source Type: Book Series    
DOI: 10.1159/000365434     Document Type: Article

References (41)

1. Vinnars B, Hammarqvist F: 25th Arvid Wretlind's Lecture-Silver anniversary, 25 years with ESPEN, the history of nutrition. Clin Nutr 2004;23:955-962.
2. Lunn M, Fausnight T: Hypersensitivity to total parenteral nutrition fat-emulsion component in an eggallergic child. Pediatrics 2011;128:1025-1028.
3. Gura KM, Parsons SK, Bechard LJ, et al: Use of a fish oil-based lipid emulsion to treat essential fatty acid deficiency in a soy allergic patient receiving parenteral nutrition. Clin Nutr 2005;24:839-847.
4. Driscoll DF: Lipid injectable emulsions: 2006. Nutr Clin Pract 2006;21:381-386.
5. Mirtallo JM, Dasta JF, Kleinschmidt KC, et al: State of the art review: Intravenous fat emulsions: current applications, safety profile, and clinical implications. Ann Pharmacother 2010;44:688-700.
6. Safe practices for parenteral nutrition formulations. National Advisory Group on Standards and Practice Guidelines for Parenteral Nutrition. JPEN J Parenter Enteral Nutr 1998;22:49-66.
7. Gura KM, Puder M: Rapid infusion of fish oil-based emulsions in infants does not appear to be associated with fat overload syndrome. Nutr Clin Pract 2010;25:399-402.
8. Vanek VW, Seidner DL, Bistrian B, et al: A. S. P. E. N. position paper: clinical role for alternative intravenous fat emulsions. Nutr Clin Pract 2012;27:150-192.
9. Singer P, Berger MM, Van Den Berghe G, et al: ESPEN Guidelines on Parenteral Nutrition: intensive care. Clin Nutr 2009;28:387-400.
10. Kalfarentzos F, Kokkinis K, Leukaditi K, et al: Comparison between two fat emulsions: Intralipid 30 cent vs Intralipid 10 cent in critically ill patients. Clin Nutr 1998;17:31-34.
11. Tillman EM: Review and clinical update on parenteral nutrition-associated liver disease. Nutr Clin Pract 2013;28:30-39.
12. Cavicchi M, Beau P, Crenn P, et al: Prevalence of liver disease and contributing factors in patients receiving home parenteral nutrition for permanent intestinal failure. Ann Intern Med 2000;132:525-532.
13. Staun M, Pironi L, Bozzetti F, et al: ESPEN Guidelines on Parenteral Nutrition: home parenteral nutrition (HPN) in adult patients. Clin Nutr 2009;28:467-479.
14. Ugur A, Marashdeh B, Gottschalck I, et al: Home parenteral nutrition in Denmark in the period from 1996 to 2001. Scand J Gastroenterol 2006;41:401-407.
15. Clayton PT, Bowron A, Mills KA, et al: Phytosterolemia in children with parenteral nutrition-associated cholestatic liver disease. Gastroenterology 1993;105:1806-1813.
16. Llop JM, Virgili N, Moreno-Villares JM, et al: Phytosterolemia in parenteral nutrition patients: implications for liver disease development. Nutrition 2008;24:1145-1152.
17. Goulet O, Joly F, Corriol O, et al: Some new insights in intestinal failure-associated liver disease. Curr Opin Organ Transplant 2009;14:256-261.
18. Puder M, Valim C, Meisel JA, et al: Parenteral fish oil improves outcomes in patients with parenteral nutrition-associated liver injury. Ann Surg 2009;250:395-402.
19. Gura KM, Lee S, Valim C, et al: Safety and efficacy of a fish-oil-based fat emulsion in the treatment of parenteral nutrition-associated liver disease. Pediatrics 2008;121:678-686.
20. Diamond IR, Sterescu A, Pencharz PB, et al: Changing the paradigm: omegaven for the treatment of liver failure in pediatric short bowel syndrome. J Pediatr Gastroenterol Nutr 2009;48:209-215.
21. Goulet O, Antebi H, Wolf C, et al: A new intravenous fat emulsion containing soybean oil, medium-chain triglycerides, olive oil, and fish oil: a single-center, double-blind randomized study on efficacy and safety in pediatric patients receiving home parenteral nutrition. JPEN J Parenter Enteral Nutr 2010;34:485-495.
22. Seida JC, Mager DR, Hartling L, et al: Parenteral ω-3 fatty acid lipid emulsions for children with intestinal failure and other conditions: a systematic review. JPEN J Parenter Enteral Nutr 2013;37:44-55.
23. De Meijer VE, Le HD, Meisel JA, et al: Parenteral fish oil as monotherapy prevents essential fatty acid deficiency in parenteral nutrition-dependent patients. J Pediatr Gastroenterol Nutr 2010;50:212-218.
24. Cober MP, Killu G, Brattain A, et al: Intravenous fat emulsions reduction for patients with parenteral nutrition-associated liver disease. J Pediatr 2012;160:421-427.
25. Iyer KR, Spitz L, Clayton P: New insight into mechanisms of parenteral nutrition-associated cholestasis: role of plant sterols. J Pediatr Surg 1998;33:1-6.
26. Aksnes J, Borsum K, Rollag H, et al: Intravascular lung macrophages play an essential role in lipid entrapment and the inflammatory tissue reaction seen after long-term lipid-based parenteral nutrition in pigs. An ultrastructural study. APMIS 1996;104:429-436.
27. Lekka ME, Liokatis S, Nathanail C, et al: The impact of intravenous fat emulsion administration in acute lung injury. Am J Respir Crit Care Med 2004;169:638-644.
28. Abbott WC, Grakauskas AM, Bistrian BR, et al: Metabolic and respiratory effects of continuous and discontinuous lipid infusions. Occurrence in excess of resting energy expenditure. Arch Surg 1984;119:1367-1371.
29. Schepens MA, Roelofs HM, Peters WH, et al: No evidence for oxidative stress in patients on home parenteral nutrition. Clin Nutr 2006;25:939-948.
30. Lennon C, Davidson KW, Sadowski JA, et al: The vitamin K concentration of intravenous lipid emulsions. JPEN J Parenter Enteral Nutr 1993;17:142-144.
31. Brown WV, Bays H, Harris W, et al: Using omega-3 fatty acids in the practice of clinical lipidology. J Clin Lipidol 2011;5:424-433.
32. Kim CH, Lewis DE, Kumar A: Bacterial and fungal growth in intravenous fat emulsions. Am J Hosp Pharm 1983;40:2159-2161.
33. Miles EA, Calder PC: Fatty acids, lipid emulsions and the immune and inflammatory systems; in Calder PC, Waitzberg DL, Koletzko B (eds): Intravenous Lipid Emulsions. World Rev Nutr Diet. Basel, Karger, 2015, vol 112, pp 17-30.
34. Furukawa K, Yamamori H, Takagi K, et al: Influences of soybean oil emulsion on stress response and cell-mediated immune function in moderately or severely stressed patients. Nutrition 2002;18:235-240.
35. Perioperative total parenteral nutrition in surgical patients. The Veterans Affairs Total Parenteral Nutrition Cooperative Study Group. N Engl J Med 1991;325:525-532.
36. Heyland DK, MacDonald S, Keefe L, et al: Total parenteral nutrition in the critically ill patient: a metaanalysis. JAMA 1998;280:2013-2019.
37. Batistella FD, Widergren JT, Andersen JT, et al: A prospective, randomized trial of intravenous fat emulsion administration in trauma victims requiring total parenteral nutrition. J Trauma 1997;43:52-58.
38. Wirtitsch M, Wessner B, Spittler A, et al: Effect of different lipid emulsions on the immunological function in humans: a systematic review with meta analysis. Clin Nutr 2007;26:302-313.
39. Pontes-Arruda A, Liu FX, Turpin RS, et al: Bloodstream infections in patients receiving manufactured parenteral nutrition with vs without lipids: is the use of lipids really deleterious? JPEN J Parenter Enteral Nutr 2012;36:421-430.
40. Chen B, Zhou Y, Yang P, et al: Safety and efficacy of fish oil-enriched parenteral nutrition regimen on postoperative patients undergoing major abdominal surgery: a meta-analysis of randomized controlled trials. JPEN J Parenter Enteral Nutr 2010;34:387-394.
41. Wei C, Hua J, Bin C, et al: Impact of lipid emulsion containing fish oil on outcomes of surgical patients: systematic review of randomized controlled trials from Europe and Asia. Nutrition 2010;26:474-481.