Folate receptor-mediated enhanced and specific delivery of far-red light-activatable prodrugs of combretastatin A-4 to FR-positive tumor

Bioconjugate Chemistry

Volumn 25, Issue 12, 2014, Pages 2175-2188

  Nkepang, Gregory ^a   Bio, Moses ^a   Rajaputra, Pallavi ^a   Awuah, Samuel G ^a   You, Youngjae ^a,b  

^a UNIVERSITY OF OKLAHOMA COLLEGE OF PHARMACY   (United States)

^b UNIVERSITY OF OKLAHOMA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOTHERAPY; CONTROLLED DRUG DELIVERY; DRUG PRODUCTS; FLUORESCENCE IMAGING; TARGETED DRUG DELIVERY;

ANTICANCER DRUG; DRUG RELEASE; FAR-RED LIGHTS; FLUORESCENCE IMAGING; FOLATE RECEPTOR; FOLIC ACIDS; MULTIFUNCTIONALITY; NEAR-IR LIGHT; PHOTODYNAMIC PROCESS; PRODRUGS;

TUMORS;

COMBRETASTATIN A4; FOLATE RECEPTOR; FOLIC ACID; PRODRUG; SINGLET OXYGEN; ANTINEOPLASTIC AGENT; COMBRETASTATIN A4 PHOSPHATE; STILBENE DERIVATIVE;

ABSORPTION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG DELIVERY SYSTEM; DRUG DESIGN; DRUG DISTRIBUTION; DRUG FORMULATION; DRUG RELEASE; DRUG SYNTHESIS; FEMALE; FLUORESCENCE IMAGING; HYDROPHILICITY; ILLUMINATION; LIGHT; MOUSE; NEOPLASM; NONHUMAN; PHOTOTOXICITY; TISSUE DISTRIBUTION; ANIMAL; BAGG ALBINO MOUSE; CHEMICAL STRUCTURE; CHEMISTRY; COLONIC NEOPLASMS; DRUG EFFECTS; DRUG SCREENING; METABOLISM; PATHOLOGY; PHOTOCHEMOTHERAPY; PROCEDURES; TUMOR CELL LINE;

MUS;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; CELL LINE, TUMOR; COLONIC NEOPLASMS; DRUG DESIGN; FEMALE; FOLATE RECEPTORS, GPI-ANCHORED; FOLIC ACID; MICE, INBRED BALB C; MOLECULAR STRUCTURE; OPTICAL IMAGING; PHOTOCHEMOTHERAPY; PRODRUGS; STILBENES; TISSUE DISTRIBUTION; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84918533922     PISSN: 10431802     EISSN: 15204812     Source Type: Journal    
DOI: 10.1021/bc500376j     Document Type: Article

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