Site-specific and far-red-light-activatable prodrug of combretastatin A-4 using photo-unclick chemistry

Journal of Medicinal Chemistry

Volumn 56, Issue 10, 2013, Pages 3936-3942

  Bio, Moses ^a   Rajaputra, Pallavi ^a,b   Nkepang, Gregory ^a,b   Awuah, Samuel G ^a   Hossion, Abugafar M L ^a   You, Youngjae ^a,b  

^a UNIVERSITY OF OKLAHOMA   (United States)

^b UNIVERSITY OF OKLAHOMA COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CADMIUM CHLORIDE; COMBRETASTATIN A4; CYTIDINE PHOSPHATE; DITHIAPORPHYRIN; PORPHYRIN DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL STRAIN MCF 7; CLICK CHEMISTRY; COLON CANCER; CONTROLLED STUDY; CROSS LINKING; CYTOTOXICITY; DIODE LASER; DRUG RELEASE; DRUG SYNTHESIS; FAR RED LIGHT; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PHOTOACTIVATION; PHOTOCHEMISTRY; TISSUE CULTURE;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; CELL LINE, TUMOR; CHEMISTRY, PHARMACEUTICAL; COLORING AGENTS; CROSS-LINKING REAGENTS; DARKNESS; DERMATITIS, PHOTOTOXIC; FLUORESCENT DYES; LIGHT; MICE; MICE, INBRED BALB C; NEOPLASM TRANSPLANTATION; PORPHYRINS; PRODRUGS; STILBENES; STRUCTURE-ACTIVITY RELATIONSHIP; TETRAZOLIUM SALTS; THIAZOLES; TUBULIN;

EID: 84878096448     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm400139w     Document Type: Article

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