-
1
-
-
33847711060
-
The power to reduce: pyridine nucleotides - small molecules with a multitude of functions
-
Pollak N., Dolle C., Ziegler M. The power to reduce: pyridine nucleotides - small molecules with a multitude of functions. Biochem. J. 2007, 402:205-218.
-
(2007)
Biochem. J.
, vol.402
, pp. 205-218
-
-
Pollak, N.1
Dolle, C.2
Ziegler, M.3
-
2
-
-
0033532508
-
Modulation of cytochrome c-mediated extramitochondrial NADH oxidation by contact site density
-
Marzulli D., La Piana G., Fransvea E., Lofrumento N.E. Modulation of cytochrome c-mediated extramitochondrial NADH oxidation by contact site density. Biochem. Biophys. Res. Commun. 1999, 259:325-330.
-
(1999)
Biochem. Biophys. Res. Commun.
, vol.259
, pp. 325-330
-
-
Marzulli, D.1
La Piana, G.2
Fransvea, E.3
Lofrumento, N.E.4
-
3
-
-
0035170286
-
Stoichiometry and compartmentation of NADH metabolism in Saccharomyces cerevisiae
-
Bakker B.M., Overkamp K.M., van Maris A.J., Kotter P., Luttik M.A., van Dijken J.P., Pronk J.T. Stoichiometry and compartmentation of NADH metabolism in Saccharomyces cerevisiae. FEMS Microbiol. Rev. 2001, 25:15-37.
-
(2001)
FEMS Microbiol. Rev.
, vol.25
, pp. 15-37
-
-
Bakker, B.M.1
Overkamp, K.M.2
van Maris, A.J.3
Kotter, P.4
Luttik, M.A.5
van Dijken, J.P.6
Pronk, J.T.7
-
4
-
-
0347419305
-
The molecular machinery of Keilin's respiratory chain
-
Rich P.R. The molecular machinery of Keilin's respiratory chain. Biochem. Soc. Trans. 2003, 31:1095-1105.
-
(2003)
Biochem. Soc. Trans.
, vol.31
, pp. 1095-1105
-
-
Rich, P.R.1
-
5
-
-
77951023118
-
Toward a unified nomenclature for mammalian ADP-ribosyltransferases
-
Hottiger M.O., Hassa P.O., Luscher B., Schuler H., Koch-Nolte F. Toward a unified nomenclature for mammalian ADP-ribosyltransferases. Trends Biochem. Sci. 2010, 35:208-219.
-
(2010)
Trends Biochem. Sci.
, vol.35
, pp. 208-219
-
-
Hottiger, M.O.1
Hassa, P.O.2
Luscher, B.3
Schuler, H.4
Koch-Nolte, F.5
-
6
-
-
70350441907
-
The role of sirtuins in the control of metabolic homeostasis
-
Yu J., Auwerx J. The role of sirtuins in the control of metabolic homeostasis. Ann. N.Y. Acad. Sci. 2009, 1173(Suppl. 1):E10-E19.
-
(2009)
Ann. N.Y. Acad. Sci.
, vol.1173
, pp. E10-E19
-
-
Yu, J.1
Auwerx, J.2
-
7
-
-
55549139051
-
The expanding field of poly(ADP-ribosyl)ation reactions. 'Protein modifications: beyond the usual suspects' review series
-
Hakme A., Wong H.K., Dantzer F., Schreiber V. The expanding field of poly(ADP-ribosyl)ation reactions. 'Protein modifications: beyond the usual suspects' review series. EMBO Rep. 2008, 9:1094-1100.
-
(2008)
EMBO Rep.
, vol.9
, pp. 1094-1100
-
-
Hakme, A.1
Wong, H.K.2
Dantzer, F.3
Schreiber, V.4
-
8
-
-
34249827266
-
Regulation of chromatin structure and chromatin-dependent transcription by poly(ADP-ribose) polymerase-1: possible targets for drug-based therapies
-
Wacker D.A., Frizzell K.M., Zhang T., Kraus W.L. Regulation of chromatin structure and chromatin-dependent transcription by poly(ADP-ribose) polymerase-1: possible targets for drug-based therapies. Subcell. Biochem. 2007, 41:45-69.
-
(2007)
Subcell. Biochem.
, vol.41
, pp. 45-69
-
-
Wacker, D.A.1
Frizzell, K.M.2
Zhang, T.3
Kraus, W.L.4
-
9
-
-
44649130038
-
Transcriptional control by PARP-1: chromatin modulation, enhancer-binding, coregulation, and insulation
-
Kraus W.L. Transcriptional control by PARP-1: chromatin modulation, enhancer-binding, coregulation, and insulation. Curr. Opin. Cell Biol. 2008, 20:294-302.
-
(2008)
Curr. Opin. Cell Biol.
, vol.20
, pp. 294-302
-
-
Kraus, W.L.1
-
10
-
-
67649888368
-
Molecular mechanism of poly(ADP-ribosyl)ation by PARP1 and identification of lysine residues as ADP-ribose acceptor sites
-
Altmeyer M., Messner S., Hassa P.O., Fey M., Hottiger M.O. Molecular mechanism of poly(ADP-ribosyl)ation by PARP1 and identification of lysine residues as ADP-ribose acceptor sites. Nucleic Acids Res. 2009, 37:3723-3738.
-
(2009)
Nucleic Acids Res.
, vol.37
, pp. 3723-3738
-
-
Altmeyer, M.1
Messner, S.2
Hassa, P.O.3
Fey, M.4
Hottiger, M.O.5
-
11
-
-
38449088040
-
The diverse biological roles of mammalian PARPS, a small but powerful family of poly-ADP-ribose polymerases
-
Hassa P.O., Hottiger M.O. The diverse biological roles of mammalian PARPS, a small but powerful family of poly-ADP-ribose polymerases. Front. Biosci. 2008, 13:3046-3082.
-
(2008)
Front. Biosci.
, vol.13
, pp. 3046-3082
-
-
Hassa, P.O.1
Hottiger, M.O.2
-
12
-
-
79952599748
-
Poly(ADP-ribose) polymerase 3 (PARP3), a newcomer in cellular response to DNA damage and mitotic progression
-
Boehler C., Gauthier L.R., Mortusewicz O., Biard D.S., Saliou J.M., Bresson A., Sanglier-Cianferani S., Smith S., Schreiber V., Boussin F., Dantzer F. Poly(ADP-ribose) polymerase 3 (PARP3), a newcomer in cellular response to DNA damage and mitotic progression. Proc. Natl. Acad. Sci. U.S.A. 2011, 108:2783-2788.
-
(2011)
Proc. Natl. Acad. Sci. U.S.A.
, vol.108
, pp. 2783-2788
-
-
Boehler, C.1
Gauthier, L.R.2
Mortusewicz, O.3
Biard, D.S.4
Saliou, J.M.5
Bresson, A.6
Sanglier-Cianferani, S.7
Smith, S.8
Schreiber, V.9
Boussin, F.10
Dantzer, F.11
-
13
-
-
78650756134
-
PARP-3 and APLF function together to accelerate nonhomologous end-joining
-
Rulten S.L., Fisher A.E., Robert I., Zuma M.C., Rouleau M., Ju L., Poirier G., Reina-San-Martin B., Caldecott K.W. PARP-3 and APLF function together to accelerate nonhomologous end-joining. Mol. Cell 2011, 41:33-45.
-
(2011)
Mol. Cell
, vol.41
, pp. 33-45
-
-
Rulten, S.L.1
Fisher, A.E.2
Robert, I.3
Zuma, M.C.4
Rouleau, M.5
Ju, L.6
Poirier, G.7
Reina-San-Martin, B.8
Caldecott, K.W.9
-
14
-
-
33847618236
-
Mammalian single-strand break repair: mechanisms and links with chromatin
-
Caldecott K.W. Mammalian single-strand break repair: mechanisms and links with chromatin. DNA Repair (Amst) 2007, 6:443-453.
-
(2007)
DNA Repair (Amst)
, vol.6
, pp. 443-453
-
-
Caldecott, K.W.1
-
15
-
-
0023340731
-
Four genes responsible for a position effect on expression from HML and HMR in Saccharomyces cerevisiae
-
Rine J., Herskowitz I. Four genes responsible for a position effect on expression from HML and HMR in Saccharomyces cerevisiae. Genetics 1987, 116:9-22.
-
(1987)
Genetics
, vol.116
, pp. 9-22
-
-
Rine, J.1
Herskowitz, I.2
-
16
-
-
84903847639
-
Sirtuins, metabolism, and DNA repair
-
Choi J.E., Mostoslavsky R. Sirtuins, metabolism, and DNA repair. Curr. Opin. Genet. Dev. 2014, 26C:24-32.
-
(2014)
Curr. Opin. Genet. Dev.
, vol.26 C
, pp. 24-32
-
-
Choi, J.E.1
Mostoslavsky, R.2
-
18
-
-
0034703217
-
Requirement of NAD and SIR2 for life-span extension by calorie restriction in Saccharomyces cerevisiae
-
Lin S.J., Defossez P.A., Guarente L. Requirement of NAD and SIR2 for life-span extension by calorie restriction in Saccharomyces cerevisiae. Science 2000, 289:2126-2128.
-
(2000)
Science
, vol.289
, pp. 2126-2128
-
-
Lin, S.J.1
Defossez, P.A.2
Guarente, L.3
-
19
-
-
3943054839
-
The Sir2 family of protein deacetylases
-
Blander G., Guarente L. The Sir2 family of protein deacetylases. Annu. Rev. Biochem. 2004, 73:417-435.
-
(2004)
Annu. Rev. Biochem.
, vol.73
, pp. 417-435
-
-
Blander, G.1
Guarente, L.2
-
20
-
-
77953631698
-
The secret life of NAD+: an old metabolite controlling new metabolic signaling pathways
-
Houtkooper R.H., Canto C., Wanders R.J., Auwerx J. The secret life of NAD+: an old metabolite controlling new metabolic signaling pathways. Endocr. Rev. 2010, 31:194-223.
-
(2010)
Endocr. Rev.
, vol.31
, pp. 194-223
-
-
Houtkooper, R.H.1
Canto, C.2
Wanders, R.J.3
Auwerx, J.4
-
21
-
-
0027253141
-
Overproduction of the poly(ADP-ribose) polymerase DNA-binding domain blocks alkylation-induced DNA repair synthesis in mammalian cells
-
Molinete M., Vermeulen W., Burkle A., Menissier-de Murcia J., Kupper J.H., Hoeijmakers J.H., de Murcia G. Overproduction of the poly(ADP-ribose) polymerase DNA-binding domain blocks alkylation-induced DNA repair synthesis in mammalian cells. EMBO J. 1993, 12:2109-2117.
-
(1993)
EMBO J.
, vol.12
, pp. 2109-2117
-
-
Molinete, M.1
Vermeulen, W.2
Burkle, A.3
Menissier-de Murcia, J.4
Kupper, J.H.5
Hoeijmakers, J.H.6
de Murcia, G.7
-
22
-
-
0029000890
-
A dominant-negative mutant of human poly(ADP-ribose) polymerase affects cell recovery, apoptosis, and sister chromatid exchange following DNA damage
-
Schreiber V., Hunting D., Trucco C., Gowans B., Grunwald D., De Murcia G., De Murcia J.M. A dominant-negative mutant of human poly(ADP-ribose) polymerase affects cell recovery, apoptosis, and sister chromatid exchange following DNA damage. Proc. Natl. Acad. Sci. U.S.A. 1995, 92:4753-4757.
-
(1995)
Proc. Natl. Acad. Sci. U.S.A.
, vol.92
, pp. 4753-4757
-
-
Schreiber, V.1
Hunting, D.2
Trucco, C.3
Gowans, B.4
Grunwald, D.5
De Murcia, G.6
De Murcia, J.M.7
-
23
-
-
0029147011
-
Molecular genetic systems to study the role of poly(ADP-ribosyl)ation in the cellular response to DNA damage
-
Kupper J.H., van Gool L., Burkle A. Molecular genetic systems to study the role of poly(ADP-ribosyl)ation in the cellular response to DNA damage. Biochimie 1995, 77:450-455.
-
(1995)
Biochimie
, vol.77
, pp. 450-455
-
-
Kupper, J.H.1
van Gool, L.2
Burkle, A.3
-
24
-
-
0028145365
-
Depletion of nuclear poly(ADP-ribose) polymerase by antisense RNA expression: influences on genomic stability, chromatin organization, and carcinogen cytotoxicity
-
Ding R., Smulson M. Depletion of nuclear poly(ADP-ribose) polymerase by antisense RNA expression: influences on genomic stability, chromatin organization, and carcinogen cytotoxicity. Cancer Res. 1994, 54:4627-4634.
-
(1994)
Cancer Res.
, vol.54
, pp. 4627-4634
-
-
Ding, R.1
Smulson, M.2
-
25
-
-
0034109623
-
The response of Parp knockout mice against DNA damaging agents
-
Masutani M., Nozaki T., Nakamoto K., Nakagama H., Suzuki H., Kusuoka O., Tsutsumi M., Sugimura T. The response of Parp knockout mice against DNA damaging agents. Mutat. Res. 2000, 462:159-166.
-
(2000)
Mutat. Res.
, vol.462
, pp. 159-166
-
-
Masutani, M.1
Nozaki, T.2
Nakamoto, K.3
Nakagama, H.4
Suzuki, H.5
Kusuoka, O.6
Tsutsumi, M.7
Sugimura, T.8
-
26
-
-
0033539651
-
Chromosomal aberrations in PARP(-/-) mice: genome stabilization in immortalized cells by reintroduction of poly(ADP-ribose) polymerase cDNA
-
Simbulan-Rosenthal C.M., Haddad B.R., Rosenthal D.S., Weaver Z., Coleman A., Luo R., Young H.M., Wang Z.Q., Ried T., Smulson M.E. Chromosomal aberrations in PARP(-/-) mice: genome stabilization in immortalized cells by reintroduction of poly(ADP-ribose) polymerase cDNA. Proc. Natl. Acad. Sci. U.S.A. 1999, 96:13191-13196.
-
(1999)
Proc. Natl. Acad. Sci. U.S.A.
, vol.96
, pp. 13191-13196
-
-
Simbulan-Rosenthal, C.M.1
Haddad, B.R.2
Rosenthal, D.S.3
Weaver, Z.4
Coleman, A.5
Luo, R.6
Young, H.M.7
Wang, Z.Q.8
Ried, T.9
Smulson, M.E.10
-
27
-
-
0032102896
-
DNA repair defect in poly(ADP-ribose) polymerase-deficient cell lines
-
Trucco C., Oliver F.J., de Murcia G., Menissier-de Murcia J. DNA repair defect in poly(ADP-ribose) polymerase-deficient cell lines. Nucleic Acids Res. 1998, 26:2644-2649.
-
(1998)
Nucleic Acids Res.
, vol.26
, pp. 2644-2649
-
-
Trucco, C.1
Oliver, F.J.2
de Murcia, G.3
Menissier-de Murcia, J.4
-
28
-
-
0030984490
-
PARP is important for genomic stability but dispensable in apoptosis
-
Wang Z.Q., Stingl L., Morrison C., Jantsch M., Los M., Schulze-Osthoff K., Wagner E.F. PARP is important for genomic stability but dispensable in apoptosis. Genes Dev. 1997, 11:2347-2358.
-
(1997)
Genes Dev.
, vol.11
, pp. 2347-2358
-
-
Wang, Z.Q.1
Stingl, L.2
Morrison, C.3
Jantsch, M.4
Los, M.5
Schulze-Osthoff, K.6
Wagner, E.F.7
-
29
-
-
33745867638
-
Poly(ADP-ribose): novel functions for an old molecule
-
Schreiber V., Dantzer F., Ame J.C., de Murcia G. Poly(ADP-ribose): novel functions for an old molecule. Nat. Rev. Mol. Cell Biol. 2006, 7:517-528.
-
(2006)
Nat. Rev. Mol. Cell Biol.
, vol.7
, pp. 517-528
-
-
Schreiber, V.1
Dantzer, F.2
Ame, J.C.3
de Murcia, G.4
-
30
-
-
0034667921
-
Base excision repair is efficient in cells lacking poly(ADP-ribose) polymerase 1
-
Vodenicharov M.D., Sallmann F.R., Satoh M.S., Poirier G.G. Base excision repair is efficient in cells lacking poly(ADP-ribose) polymerase 1. Nucleic Acids Res. 2000, 28:3887-3896.
-
(2000)
Nucleic Acids Res.
, vol.28
, pp. 3887-3896
-
-
Vodenicharov, M.D.1
Sallmann, F.R.2
Satoh, M.S.3
Poirier, G.G.4
-
31
-
-
33749260519
-
Nuclear ADP-ribosylation reactions in mammalian cells: where are we today and where are we going?
-
Hassa P.O., Haenni S.S., Elser M., Hottiger M.O. Nuclear ADP-ribosylation reactions in mammalian cells: where are we today and where are we going?. Microbiol. Mol. Biol. Rev. 2006, 70:789-829.
-
(2006)
Microbiol. Mol. Biol. Rev.
, vol.70
, pp. 789-829
-
-
Hassa, P.O.1
Haenni, S.S.2
Elser, M.3
Hottiger, M.O.4
-
32
-
-
80051670852
-
NAD+ depletion or PAR polymer formation: which plays the role of executioner in ischaemic cell death?
-
Siegel C., McCullough L.D. NAD+ depletion or PAR polymer formation: which plays the role of executioner in ischaemic cell death?. Acta Physiol. (Oxf) 2011, 203:225-234.
-
(2011)
Acta Physiol. (Oxf)
, vol.203
, pp. 225-234
-
-
Siegel, C.1
McCullough, L.D.2
-
33
-
-
2942707644
-
Human poly(ADP-ribose) glycohydrolase is expressed in alternative splice variants yielding isoforms that localize to different cell compartments
-
Meyer-Ficca M.L., Meyer R.G., Coyle D.L., Jacobson E.L., Jacobson M.K. Human poly(ADP-ribose) glycohydrolase is expressed in alternative splice variants yielding isoforms that localize to different cell compartments. Exp. Cell Res. 2004, 297:521-532.
-
(2004)
Exp. Cell Res.
, vol.297
, pp. 521-532
-
-
Meyer-Ficca, M.L.1
Meyer, R.G.2
Coyle, D.L.3
Jacobson, E.L.4
Jacobson, M.K.5
-
34
-
-
34547153717
-
Two small enzyme isoforms mediate mammalian mitochondrial poly(ADP-ribose) glycohydrolase (PARG) activity
-
Meyer R.G., Meyer-Ficca M.L., Whatcott C.J., Jacobson E.L., Jacobson M.K. Two small enzyme isoforms mediate mammalian mitochondrial poly(ADP-ribose) glycohydrolase (PARG) activity. Exp. Cell Res. 2007, 313:2920-2936.
-
(2007)
Exp. Cell Res.
, vol.313
, pp. 2920-2936
-
-
Meyer, R.G.1
Meyer-Ficca, M.L.2
Whatcott, C.J.3
Jacobson, E.L.4
Jacobson, M.K.5
-
35
-
-
63849115360
-
Parthanatos, a messenger of death
-
David K.K., Andrabi S.A., Dawson T.M., Dawson V.L. Parthanatos, a messenger of death. Front. Biosci. 2009, 14:1116-1128.
-
(2009)
Front. Biosci.
, vol.14
, pp. 1116-1128
-
-
David, K.K.1
Andrabi, S.A.2
Dawson, T.M.3
Dawson, V.L.4
-
36
-
-
33845301167
-
Poly(ADP-ribose) (PAR) polymer is a death signal
-
Andrabi S.A., Kim N.S., Yu S.W., Wang H., Koh D.W., Sasaki M., Klaus J.A., Otsuka T., Zhang Z., Koehler R.C., Hurn P.D., Poirier G.G., Dawson V.L., Dawson T.M. Poly(ADP-ribose) (PAR) polymer is a death signal. Proc. Natl. Acad. Sci. U.S.A. 2006, 103:18308-18313.
-
(2006)
Proc. Natl. Acad. Sci. U.S.A.
, vol.103
, pp. 18308-18313
-
-
Andrabi, S.A.1
Kim, N.S.2
Yu, S.W.3
Wang, H.4
Koh, D.W.5
Sasaki, M.6
Klaus, J.A.7
Otsuka, T.8
Zhang, Z.9
Koehler, R.C.10
Hurn, P.D.11
Poirier, G.G.12
Dawson, V.L.13
Dawson, T.M.14
-
37
-
-
0033521741
-
Molecular characterization of mitochondrial apoptosis-inducing factor
-
Susin S.A., Lorenzo H.K., Zamzami N., Marzo I., Snow B.E., Brothers G.M., Mangion J., Jacotot E., Costantini P., Loeffler M., Larochette N., Goodlett D.R., Aebersold R., Siderovski D.P., Penninger J.M., Kroemer G. Molecular characterization of mitochondrial apoptosis-inducing factor. Nature 1999, 397:441-446.
-
(1999)
Nature
, vol.397
, pp. 441-446
-
-
Susin, S.A.1
Lorenzo, H.K.2
Zamzami, N.3
Marzo, I.4
Snow, B.E.5
Brothers, G.M.6
Mangion, J.7
Jacotot, E.8
Costantini, P.9
Loeffler, M.10
Larochette, N.11
Goodlett, D.R.12
Aebersold, R.13
Siderovski, D.P.14
Penninger, J.M.15
Kroemer, G.16
-
38
-
-
0037067317
-
Mediation of poly(ADP-ribose) polymerase-1-dependent cell death by apoptosis-inducing factor
-
Yu S.W., Wang H., Poitras M.F., Coombs C., Bowers W.J., Federoff H.J., Poirier G.G., Dawson T.M., Dawson V.L. Mediation of poly(ADP-ribose) polymerase-1-dependent cell death by apoptosis-inducing factor. Science 2002, 297:259-263.
-
(2002)
Science
, vol.297
, pp. 259-263
-
-
Yu, S.W.1
Wang, H.2
Poitras, M.F.3
Coombs, C.4
Bowers, W.J.5
Federoff, H.J.6
Poirier, G.G.7
Dawson, T.M.8
Dawson, V.L.9
-
39
-
-
0037713529
-
Apoptosis inducing factor and PARP-mediated injury in the MPTP mouse model of Parkinson's disease
-
Wang H., Shimoji M., Yu S.W., Dawson T.M., Dawson V.L. Apoptosis inducing factor and PARP-mediated injury in the MPTP mouse model of Parkinson's disease. Ann. N.Y. Acad. Sci. 2003, 991:132-139.
-
(2003)
Ann. N.Y. Acad. Sci.
, vol.991
, pp. 132-139
-
-
Wang, H.1
Shimoji, M.2
Yu, S.W.3
Dawson, T.M.4
Dawson, V.L.5
-
40
-
-
79953840957
-
Poly(ADP-ribose) (PAR) binding to apoptosis-inducing factor is critical for PAR polymerase-1-dependent cell death (parthanatos)
-
Wang Y., Kim N.S., Haince J.F., Kang H.C., David K.K., Andrabi S.A., Poirier G.G., Dawson V.L., Dawson T.M. Poly(ADP-ribose) (PAR) binding to apoptosis-inducing factor is critical for PAR polymerase-1-dependent cell death (parthanatos). Sci. Signal 2011, 4:ra20.
-
(2011)
Sci. Signal
, vol.4
, pp. ra20
-
-
Wang, Y.1
Kim, N.S.2
Haince, J.F.3
Kang, H.C.4
David, K.K.5
Andrabi, S.A.6
Poirier, G.G.7
Dawson, V.L.8
Dawson, T.M.9
-
41
-
-
0347719407
-
Loss of poly(ADP-ribose) glycohydrolase causes progressive neurodegeneration in Drosophila melanogaster
-
Hanai S., Kanai M., Ohashi S., Okamoto K., Yamada M., Takahashi H., Miwa M. Loss of poly(ADP-ribose) glycohydrolase causes progressive neurodegeneration in Drosophila melanogaster. Proc. Natl. Acad. Sci. U.S.A. 2004, 101:82-86.
-
(2004)
Proc. Natl. Acad. Sci. U.S.A.
, vol.101
, pp. 82-86
-
-
Hanai, S.1
Kanai, M.2
Ohashi, S.3
Okamoto, K.4
Yamada, M.5
Takahashi, H.6
Miwa, M.7
-
42
-
-
19944418213
-
Failure to degrade poly(ADP-ribose) causes increased sensitivity to cytotoxicity and early embryonic lethality
-
Koh D.W., Lawler A.M., Poitras M.F., Sasaki M., Wattler S., Nehls M.C., Stoger T., Poirier G.G., Dawson V.L., Dawson T.M. Failure to degrade poly(ADP-ribose) causes increased sensitivity to cytotoxicity and early embryonic lethality. Proc. Natl. Acad. Sci. U.S.A. 2004, 101:17699-17704.
-
(2004)
Proc. Natl. Acad. Sci. U.S.A.
, vol.101
, pp. 17699-17704
-
-
Koh, D.W.1
Lawler, A.M.2
Poitras, M.F.3
Sasaki, M.4
Wattler, S.5
Nehls, M.C.6
Stoger, T.7
Poirier, G.G.8
Dawson, V.L.9
Dawson, T.M.10
-
43
-
-
33646377428
-
Poly(ADP-ribose) accumulation and enhancement of postischemic brain damage in 110-kDa poly(ADP-ribose) glycohydrolase null mice
-
Cozzi A., Cipriani G., Fossati S., Faraco G., Formentini L., Min W., Cortes U., Wang Z.Q., Moroni F., Chiarugi A. Poly(ADP-ribose) accumulation and enhancement of postischemic brain damage in 110-kDa poly(ADP-ribose) glycohydrolase null mice. J. Cereb. Blood Flow Metab. 2006, 26:684-695.
-
(2006)
J. Cereb. Blood Flow Metab.
, vol.26
, pp. 684-695
-
-
Cozzi, A.1
Cipriani, G.2
Fossati, S.3
Faraco, G.4
Formentini, L.5
Min, W.6
Cortes, U.7
Wang, Z.Q.8
Moroni, F.9
Chiarugi, A.10
-
44
-
-
19444366619
-
Role of poly(ADP-ribose) glycohydrolase (PARG) in shock, ischemia and reperfusion
-
Cuzzocrea S., Wang Z.Q. Role of poly(ADP-ribose) glycohydrolase (PARG) in shock, ischemia and reperfusion. Pharmacol. Res. 2005, 52:100-108.
-
(2005)
Pharmacol. Res.
, vol.52
, pp. 100-108
-
-
Cuzzocrea, S.1
Wang, Z.Q.2
-
45
-
-
11144305946
-
Complex H2AX phosphorylation patterns by multiple kinases including ATM and DNA-PK in human cells exposed to ionizing radiation and treated with kinase inhibitors
-
Wang H., Wang M., Wang H., Bocker W., Iliakis G. Complex H2AX phosphorylation patterns by multiple kinases including ATM and DNA-PK in human cells exposed to ionizing radiation and treated with kinase inhibitors. J. Cell. Physiol. 2005, 202:492-502.
-
(2005)
J. Cell. Physiol.
, vol.202
, pp. 492-502
-
-
Wang, H.1
Wang, M.2
Wang, H.3
Bocker, W.4
Iliakis, G.5
-
46
-
-
19444363413
-
Mice lacking the 110-kD isoform of poly(ADP-ribose) glycohydrolase are protected against renal ischemia/reperfusion injury
-
Patel N.S., Cortes U., Di Poala R., Mazzon E., Mota-Filipe H., Cuzzocrea S., Wang Z.Q., Thiemermann C. Mice lacking the 110-kD isoform of poly(ADP-ribose) glycohydrolase are protected against renal ischemia/reperfusion injury. J. Am. Soc. Nephrol. 2005, 16:712-719.
-
(2005)
J. Am. Soc. Nephrol.
, vol.16
, pp. 712-719
-
-
Patel, N.S.1
Cortes, U.2
Di Poala, R.3
Mazzon, E.4
Mota-Filipe, H.5
Cuzzocrea, S.6
Wang, Z.Q.7
Thiemermann, C.8
-
47
-
-
3042798440
-
Minichromosome maintenance proteins are direct targets of the ATM and ATR checkpoint kinases
-
Cortez D., Glick G., Elledge S.J. Minichromosome maintenance proteins are direct targets of the ATM and ATR checkpoint kinases. Proc. Natl. Acad. Sci. U.S.A. 2004, 101:10078-10083.
-
(2004)
Proc. Natl. Acad. Sci. U.S.A.
, vol.101
, pp. 10078-10083
-
-
Cortez, D.1
Glick, G.2
Elledge, S.J.3
-
48
-
-
68949178566
-
Radiation-induced mitotic catastrophe in PARG-deficient cells
-
Ame J.C., Fouquerel E., Gauthier L.R., Biard D., Boussin F.D., Dantzer F., de Murcia G., Schreiber V. Radiation-induced mitotic catastrophe in PARG-deficient cells. J. Cell Sci. 2009, 122:1990-2002.
-
(2009)
J. Cell Sci.
, vol.122
, pp. 1990-2002
-
-
Ame, J.C.1
Fouquerel, E.2
Gauthier, L.R.3
Biard, D.4
Boussin, F.D.5
Dantzer, F.6
de Murcia, G.7
Schreiber, V.8
-
49
-
-
84888110477
-
ADP-ribosyl-acceptor hydrolase 3 regulates poly (ADP-ribose) degradation and cell death during oxidative stress
-
Mashimo M., Kato J., Moss J. ADP-ribosyl-acceptor hydrolase 3 regulates poly (ADP-ribose) degradation and cell death during oxidative stress. Proc. Natl. Acad. Sci. U.S.A. 2013, 110:18964-18969.
-
(2013)
Proc. Natl. Acad. Sci. U.S.A.
, vol.110
, pp. 18964-18969
-
-
Mashimo, M.1
Kato, J.2
Moss, J.3
-
50
-
-
0020980976
-
Poly(ADP-ribose) polymerase mediates the suicide response to massive DNA damage: studies in normal and DNA-repair defective cells
-
Berger N.A., Sims J.L., Catino D.M., Berger S.J. Poly(ADP-ribose) polymerase mediates the suicide response to massive DNA damage: studies in normal and DNA-repair defective cells. Princess Takamatsu Symp. 1983, 13:219-226.
-
(1983)
Princess Takamatsu Symp.
, vol.13
, pp. 219-226
-
-
Berger, N.A.1
Sims, J.L.2
Catino, D.M.3
Berger, S.J.4
-
51
-
-
0021997074
-
Poly(ADP-ribose) in the cellular response to DNA damage
-
Berger N.A. Poly(ADP-ribose) in the cellular response to DNA damage. Radiat. Res. 1985, 101:4-15.
-
(1985)
Radiat. Res.
, vol.101
, pp. 4-15
-
-
Berger, N.A.1
-
52
-
-
0036499892
-
Poly(ADP-ribose) polymerase: killer or conspirator? The 'suicide hypothesis' revisited
-
Chiarugi A. Poly(ADP-ribose) polymerase: killer or conspirator? The 'suicide hypothesis' revisited. Trends Pharmacol. Sci. 2002, 23:122-129.
-
(2002)
Trends Pharmacol. Sci.
, vol.23
, pp. 122-129
-
-
Chiarugi, A.1
-
53
-
-
0036301275
-
Tricarboxylic acid cycle substrates prevent PARP-mediated death of neurons and astrocytes
-
Ying W., Chen Y., Alano C.C., Swanson R.A. Tricarboxylic acid cycle substrates prevent PARP-mediated death of neurons and astrocytes. J. Cereb. Blood Flow Metab. 2002, 22:774-779.
-
(2002)
J. Cereb. Blood Flow Metab.
, vol.22
, pp. 774-779
-
-
Ying, W.1
Chen, Y.2
Alano, C.C.3
Swanson, R.A.4
-
54
-
-
79952751250
-
Overcoming temozolomide resistance in glioblastoma via dual inhibition of NAD+ biosynthesis and base excision repair
-
Goellner E.M., Grimme B., Brown A.R., Lin Y.C., Wang X.H., Sugrue K.F., Mitchell L., Trivedi R.N., Tang J.B., Sobol R.W. Overcoming temozolomide resistance in glioblastoma via dual inhibition of NAD+ biosynthesis and base excision repair. Cancer Res. 2011, 71:2308-2317.
-
(2011)
Cancer Res.
, vol.71
, pp. 2308-2317
-
-
Goellner, E.M.1
Grimme, B.2
Brown, A.R.3
Lin, Y.C.4
Wang, X.H.5
Sugrue, K.F.6
Mitchell, L.7
Trivedi, R.N.8
Tang, J.B.9
Sobol, R.W.10
-
55
-
-
75149149167
-
Bioenergetic metabolites regulate base excision repair-dependent cell death in response to DNA damage
-
Tang J., Goellner E.M., Wang X.W., Trivedi R.N., St Croix C.M., Jelezcova E., Svilar D., Brown A.R., Sobol R.W. Bioenergetic metabolites regulate base excision repair-dependent cell death in response to DNA damage. Mol. Cancer Res. 2010, 8:67-79.
-
(2010)
Mol. Cancer Res.
, vol.8
, pp. 67-79
-
-
Tang, J.1
Goellner, E.M.2
Wang, X.W.3
Trivedi, R.N.4
St Croix, C.M.5
Jelezcova, E.6
Svilar, D.7
Brown, A.R.8
Sobol, R.W.9
-
56
-
-
84907405599
-
ARTD1/PARP1 negatively regulates glycolysis by inhibiting hexokinase 1 independent of NAD+ depletion
-
Fouquerel E., Goellner E.M., Yu Z., Gagne J.P., Barbi de Moura M., Feinstein T., Wheeler D., Redpath P., Li J., Romero G., Migaud M., Van Houten B., Poirier G., Sobol R.W. ARTD1/PARP1 negatively regulates glycolysis by inhibiting hexokinase 1 independent of NAD+ depletion. Cell Rep. 2014, 8:1819-1831.
-
(2014)
Cell Rep.
, vol.8
, pp. 1819-1831
-
-
Fouquerel, E.1
Goellner, E.M.2
Yu, Z.3
Gagne, J.P.4
Barbi de Moura, M.5
Feinstein, T.6
Wheeler, D.7
Redpath, P.8
Li, J.9
Romero, G.10
Migaud, M.11
Van Houten, B.12
Poirier, G.13
Sobol, R.W.14
-
57
-
-
2442624618
-
Poly(ADP-ribose) polymerase-1-mediated cell death in astrocytes requires NAD+ depletion and mitochondrial permeability transition
-
Alano C.C., Ying W., Swanson R.A. Poly(ADP-ribose) polymerase-1-mediated cell death in astrocytes requires NAD+ depletion and mitochondrial permeability transition. J. Biol. Chem. 2004, 279:18895-18902.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 18895-18902
-
-
Alano, C.C.1
Ying, W.2
Swanson, R.A.3
-
58
-
-
20444454999
-
Nuclear poly(ADP-ribose) polymerase-1 rapidly triggers mitochondrial dysfunction
-
Cipriani G., Rapizzi E., Vannacci A., Rizzuto R., Moroni F., Chiarugi A. Nuclear poly(ADP-ribose) polymerase-1 rapidly triggers mitochondrial dysfunction. J. Biol. Chem. 2005, 280:17227-17234.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 17227-17234
-
-
Cipriani, G.1
Rapizzi, E.2
Vannacci, A.3
Rizzuto, R.4
Moroni, F.5
Chiarugi, A.6
-
60
-
-
0041573041
-
NAD+ repletion prevents PARP-1-induced glycolytic blockade and cell death in cultured mouse astrocytes
-
Ying W., Garnier P., Swanson R.A. NAD+ repletion prevents PARP-1-induced glycolytic blockade and cell death in cultured mouse astrocytes. Biochem. Biophys. Res. Commun. 2003, 308:809-813.
-
(2003)
Biochem. Biophys. Res. Commun.
, vol.308
, pp. 809-813
-
-
Ying, W.1
Garnier, P.2
Swanson, R.A.3
-
61
-
-
2642536197
-
Alkylating DNA damage stimulates a regulated form of necrotic cell death
-
Zong W.X., Ditsworth D., Bauer D.E., Wang Z.Q., Thompson C.B. Alkylating DNA damage stimulates a regulated form of necrotic cell death. Genes Dev. 2004, 18:1272-1282.
-
(2004)
Genes Dev.
, vol.18
, pp. 1272-1282
-
-
Zong, W.X.1
Ditsworth, D.2
Bauer, D.E.3
Wang, Z.Q.4
Thompson, C.B.5
-
62
-
-
0033598713
-
Poly(ADP-ribose) polymerase is a mediator of necrotic cell death by ATP depletion
-
Ha H.C., Snyder S.H. Poly(ADP-ribose) polymerase is a mediator of necrotic cell death by ATP depletion. Proc. Natl. Acad. Sci. U.S.A. 1999, 96:13978-13982.
-
(1999)
Proc. Natl. Acad. Sci. U.S.A.
, vol.96
, pp. 13978-13982
-
-
Ha, H.C.1
Snyder, S.H.2
-
63
-
-
58749112769
-
Proteome-wide identification of poly(ADP-ribose) binding proteins and poly(ADP-ribose)-associated protein complexes
-
Gagne J.P., Isabelle M., Lo K.S., Bourassa S., Hendzel M.J., Dawson V.L., Dawson T.M., Poirier G.G. Proteome-wide identification of poly(ADP-ribose) binding proteins and poly(ADP-ribose)-associated protein complexes. Nucleic Acids Res. 2008, 36:6959-6976.
-
(2008)
Nucleic Acids Res.
, vol.36
, pp. 6959-6976
-
-
Gagne, J.P.1
Isabelle, M.2
Lo, K.S.3
Bourassa, S.4
Hendzel, M.J.5
Dawson, V.L.6
Dawson, T.M.7
Poirier, G.G.8
-
64
-
-
84857757702
-
Mitochondrial VDAC1: function in cell life and death and a target for cancer therapy
-
Shoshan-Barmatz V., Golan M. Mitochondrial VDAC1: function in cell life and death and a target for cancer therapy. Curr. Med. Chem. 2012, 19:714-735.
-
(2012)
Curr. Med. Chem.
, vol.19
, pp. 714-735
-
-
Shoshan-Barmatz, V.1
Golan, M.2
-
65
-
-
84904300961
-
Poly(ADP-ribose) polymerase-dependent energy depletion occurs through inhibition of glycolysis
-
Andrabi S.A., Umanah G.K., Chang C., Stevens D.A., Karuppagounder S.S., Gagne J.P., Poirier G.G., Dawson V.L., Dawson T.M. Poly(ADP-ribose) polymerase-dependent energy depletion occurs through inhibition of glycolysis. Proc. Natl. Acad. Sci. U.S.A. 2014, 111:10209-10214.
-
(2014)
Proc. Natl. Acad. Sci. U.S.A.
, vol.111
, pp. 10209-10214
-
-
Andrabi, S.A.1
Umanah, G.K.2
Chang, C.3
Stevens, D.A.4
Karuppagounder, S.S.5
Gagne, J.P.6
Poirier, G.G.7
Dawson, V.L.8
Dawson, T.M.9
-
66
-
-
78650719636
-
Amyloid-beta triggers the release of neuronal hexokinase 1 from mitochondria
-
Saraiva L.M., Seixas da Silva G.S., Galina A., da-Silva W.S., Klein W.L., Ferreira S.T., De Felice F.G. Amyloid-beta triggers the release of neuronal hexokinase 1 from mitochondria. PLoS ONE 2010, 5:e15230.
-
(2010)
PLoS ONE
, vol.5
, pp. e15230
-
-
Saraiva, L.M.1
Seixas da Silva, G.S.2
Galina, A.3
da-Silva, W.S.4
Klein, W.L.5
Ferreira, S.T.6
De Felice, F.G.7
-
67
-
-
26244436281
-
Evolutionarily conserved and nonconserved cellular localizations and functions of human SIRT proteins
-
Michishita E., Park J.Y., Burneskis J.M., Barrett J.C., Horikawa I. Evolutionarily conserved and nonconserved cellular localizations and functions of human SIRT proteins. Mol. Biol. Cell 2005, 16:4623-4635.
-
(2005)
Mol. Biol. Cell
, vol.16
, pp. 4623-4635
-
-
Michishita, E.1
Park, J.Y.2
Burneskis, J.M.3
Barrett, J.C.4
Horikawa, I.5
-
68
-
-
84886717428
-
Crosstalk between poly(ADP-ribose) polymerase and sirtuin enzymes
-
Canto C., Sauve A.A., Bai P. Crosstalk between poly(ADP-ribose) polymerase and sirtuin enzymes. Mol. Aspects Med. 2013, 34:1168-1201.
-
(2013)
Mol. Aspects Med.
, vol.34
, pp. 1168-1201
-
-
Canto, C.1
Sauve, A.A.2
Bai, P.3
-
69
-
-
70349319371
-
Functional interplay between Parp-1 and SirT1 in genome integrity and chromatin-based processes
-
El Ramy R., Magroun N., Messadecq N., Gauthier L.R., Boussin F.D., Kolthur-Seetharam U., Schreiber V., McBurney M.W., Sassone-Corsi P., Dantzer F. Functional interplay between Parp-1 and SirT1 in genome integrity and chromatin-based processes. Cell. Mol. Life Sci. 2009, 66:3219-3234.
-
(2009)
Cell. Mol. Life Sci.
, vol.66
, pp. 3219-3234
-
-
El Ramy, R.1
Magroun, N.2
Messadecq, N.3
Gauthier, L.R.4
Boussin, F.D.5
Kolthur-Seetharam, U.6
Schreiber, V.7
McBurney, M.W.8
Sassone-Corsi, P.9
Dantzer, F.10
-
70
-
-
84903998315
-
SIRT1 prevents genotoxic stress-induced p53 activation in acute myeloid leukemia
-
Sasca D., Hahnel P.S., Szybinski J., Khawaja K., Kriege O., Pante S.V., Bullinger L., Strand S., Strand D., Theobald M., Kindler T. SIRT1 prevents genotoxic stress-induced p53 activation in acute myeloid leukemia. Blood 2014, 124:121-133.
-
(2014)
Blood
, vol.124
, pp. 121-133
-
-
Sasca, D.1
Hahnel, P.S.2
Szybinski, J.3
Khawaja, K.4
Kriege, O.5
Pante, S.V.6
Bullinger, L.7
Strand, S.8
Strand, D.9
Theobald, M.10
Kindler, T.11
-
71
-
-
0035913911
-
Negative control of p53 by Sir2alpha promotes cell survival under stress
-
Luo J., Nikolaev A.Y., Imai S., Chen D., Su F., Shiloh A., Guarente L., Gu W. Negative control of p53 by Sir2alpha promotes cell survival under stress. Cell 2001, 107:137-148.
-
(2001)
Cell
, vol.107
, pp. 137-148
-
-
Luo, J.1
Nikolaev, A.Y.2
Imai, S.3
Chen, D.4
Su, F.5
Shiloh, A.6
Guarente, L.7
Gu, W.8
-
72
-
-
0035913903
-
HSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase
-
Vaziri H., Dessain S.K., Ng Eaton E., Imai S.I., Frye R.A., Pandita T.K., Guarente L., Weinberg R.A. hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase. Cell 2001, 107:149-159.
-
(2001)
Cell
, vol.107
, pp. 149-159
-
-
Vaziri, H.1
Dessain, S.K.2
Ng Eaton, E.3
Imai, S.I.4
Frye, R.A.5
Pandita, T.K.6
Guarente, L.7
Weinberg, R.A.8
-
73
-
-
28644447272
-
The antioxidant function of the p53 tumor suppressor
-
Sablina A.A., Budanov A.V., Ilyinskaya G.V., Agapova L.S., Kravchenko J.E., Chumakov P.M. The antioxidant function of the p53 tumor suppressor. Nat. Med. 2005, 11:1306-1313.
-
(2005)
Nat. Med.
, vol.11
, pp. 1306-1313
-
-
Sablina, A.A.1
Budanov, A.V.2
Ilyinskaya, G.V.3
Agapova, L.S.4
Kravchenko, J.E.5
Chumakov, P.M.6
-
74
-
-
33744475759
-
Control of AIF-mediated cell death by the functional interplay of SIRT1 and PARP-1 in response to DNA damage
-
Kolthur-Seetharam U., Dantzer F., McBurney M.W., de Murcia G., Sassone-Corsi P. Control of AIF-mediated cell death by the functional interplay of SIRT1 and PARP-1 in response to DNA damage. Cell Cycle 2006, 5:873-877.
-
(2006)
Cell Cycle
, vol.5
, pp. 873-877
-
-
Kolthur-Seetharam, U.1
Dantzer, F.2
McBurney, M.W.3
de Murcia, G.4
Sassone-Corsi, P.5
-
75
-
-
12144290563
-
Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase
-
Brunet A., Sweeney L.B., Sturgill J.F., Chua K.F., Greer P.L., Lin Y., Tran H., Ross S.E., Mostoslavsky R., Cohen H.Y., Hu L.S., Cheng H.L., Jedrychowski M.P., Gygi S.P., Sinclair D.A., Alt F.W., Greenberg M.E. Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase. Science 2004, 303:2011-2015.
-
(2004)
Science
, vol.303
, pp. 2011-2015
-
-
Brunet, A.1
Sweeney, L.B.2
Sturgill, J.F.3
Chua, K.F.4
Greer, P.L.5
Lin, Y.6
Tran, H.7
Ross, S.E.8
Mostoslavsky, R.9
Cohen, H.Y.10
Hu, L.S.11
Cheng, H.L.12
Jedrychowski, M.P.13
Gygi, S.P.14
Sinclair, D.A.15
Alt, F.W.16
Greenberg, M.E.17
-
76
-
-
31044445366
-
Genomic instability and aging-like phenotype in the absence of mammalian SIRT6
-
Mostoslavsky R., Chua K.F., Lombard D.B., Pang W.W., Fischer M.R., Gellon L., Liu P., Mostoslavsky G., Franco S., Murphy M.M., Mills K.D., Patel P., Hsu J.T., Hong A.L., Ford E., Cheng H.L., Kennedy C., Nunez N., Bronson R., Frendewey D., Auerbach W., Valenzuela D., Karow M., Hottiger M.O., Hursting S., Barrett J.C., Guarente L., Mulligan R., Demple B., Yancopoulos G.D., Alt F.W. Genomic instability and aging-like phenotype in the absence of mammalian SIRT6. Cell 2006, 124:315-329.
-
(2006)
Cell
, vol.124
, pp. 315-329
-
-
Mostoslavsky, R.1
Chua, K.F.2
Lombard, D.B.3
Pang, W.W.4
Fischer, M.R.5
Gellon, L.6
Liu, P.7
Mostoslavsky, G.8
Franco, S.9
Murphy, M.M.10
Mills, K.D.11
Patel, P.12
Hsu, J.T.13
Hong, A.L.14
Ford, E.15
Cheng, H.L.16
Kennedy, C.17
Nunez, N.18
Bronson, R.19
Frendewey, D.20
Auerbach, W.21
Valenzuela, D.22
Karow, M.23
Hottiger, M.O.24
Hursting, S.25
Barrett, J.C.26
Guarente, L.27
Mulligan, R.28
Demple, B.29
Yancopoulos, G.D.30
Alt, F.W.31
more..
|