메뉴 건너뛰기




Volumn 35, Issue 1, 2015, Pages 31-38

Scutellarein inhibits cancer cell metastasis in vitro and attenuates the development of fibrosarcoma in vivo

Author keywords

HT1080 cells; Invasion; Matrix metalloproteinase; Metastasis; Scutellarein

Indexed keywords

ANTINEOPLASTIC AGENT; DIMETHYL SULFOXIDE; GELATINASE A; GELATINASE B; I KAPPA B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MATRIX METALLOPROTEINASE 14; RECEPTOR ACTIVATOR OF NUCLEAR FACTOR KAPPA B; SCUTELLAREIN; APIGENIN; MATRIX METALLOPROTEINASE;

EID: 84917708546     PISSN: 11073756     EISSN: 1791244X     Source Type: Journal    
DOI: 10.3892/ijmm.2014.1997     Document Type: Article
Times cited : (46)

References (32)
  • 1
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: The next generation
    • Hanahan D and Weinberg RA: Hallmarks of cancer: the next generation. Cell 144: 646-674, 2011.
    • (2011) Cell , vol.144 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 2
    • 63049104211 scopus 로고    scopus 로고
    • Microenvironmental regulation of metastasis
    • Joyce JA and Pollard JW: Microenvironmental regulation of metastasis. Nat Rev Cancer 9: 239-252, 2009.
    • (2009) Nat Rev Cancer , vol.9 , pp. 239-252
    • Joyce, J.A.1    Pollard, J.W.2
  • 3
    • 63049121364 scopus 로고    scopus 로고
    • The metastatic niche: Adapting the foreign soil
    • Psaila B and Lyden D: The metastatic niche: adapting the foreign soil. Nat Rev Cancer 9: 285-293, 2009.
    • (2009) Nat Rev Cancer , vol.9 , pp. 285-293
    • Psaila, B.1    Lyden, D.2
  • 5
    • 0021714105 scopus 로고
    • Tumor invasion and metastases: Role of the basement membrane. Warner-Lambert Parke-Davis Award lecture
    • Liotta LA: Tumor invasion and metastases: role of the basement membrane. Warner-Lambert Parke-Davis Award lecture. Am J Pathol 117: 339-348, 1984.
    • (1984) Am J Pathol , vol.117 , pp. 339-348
    • Liotta, L.A.1
  • 6
    • 0036512208 scopus 로고    scopus 로고
    • New functions for the matrix metalloproteinases in cancer progression
    • Egeblad M and Werb Z: New functions for the matrix metalloproteinases in cancer progression. Nat Rev Cancer 2: 161-174, 2002.
    • (2002) Nat Rev Cancer , vol.2 , pp. 161-174
    • Egeblad, M.1    Werb, Z.2
  • 7
    • 0033618337 scopus 로고    scopus 로고
    • Matrix metalloproteinases
    • Nagase H and Woessner JF Jr: Matrix metalloproteinases. J Biol Chem 274: 21491-21494, 1999.
    • (1999) J Biol Chem , vol.274 , pp. 21491-21494
    • Nagase, H.1    Woessner, J.F.2
  • 8
    • 0037693895 scopus 로고    scopus 로고
    • Matrix metalloproteinases and tissue inhibitors of metalloproteinases: Structure, function, and biochemistry
    • Visse R and Nagase H: Matrix metalloproteinases and tissue inhibitors of metalloproteinases: structure, function, and biochemistry. Circ Res 92: 827-839, 2003.
    • (2003) Circ Res , vol.92 , pp. 827-839
    • Visse, R.1    Nagase, H.2
  • 9
    • 33646576169 scopus 로고    scopus 로고
    • Matrix metalloproteinases and tumor metastasis
    • Deryugina EI and Quigley JP: Matrix metalloproteinases and tumor metastasis. Cancer Metastasis Rev 25: 9-34, 2006.
    • (2006) Cancer Metastasis Rev , vol.25 , pp. 9-34
    • Deryugina, E.I.1    Quigley, J.P.2
  • 10
    • 33745684527 scopus 로고    scopus 로고
    • Metastasis: A question of life or death
    • Mehlen P and Puisieux A: Metastasis: a question of life or death. Nat Rev Cancer 6: 449-458, 2006.
    • (2006) Nat Rev Cancer , vol.6 , pp. 449-458
    • Mehlen, P.1    Puisieux, A.2
  • 11
    • 34447269445 scopus 로고    scopus 로고
    • Matrix metalloproteinase inhibitors: New challenges in the era of post broad-spectrum inhibitors
    • Nuti E, Tuccinardi T and Rossello A: Matrix metalloproteinase inhibitors: new challenges in the era of post broad-spectrum inhibitors. Curr Pharm Des 13: 2087-2100, 2007.
    • (2007) Curr Pharm des , vol.13 , pp. 2087-2100
    • Nuti, E.1    Tuccinardi, T.2    Rossello, A.3
  • 12
    • 44849101717 scopus 로고    scopus 로고
    • Scutellarein inhibits hypoxia- and moderately-high glucose-induced proliferation and VEGF expression in human retinal endothelial cells
    • Gao R, Zhu BH, Tang SB, Wang JF and Ren J: Scutellarein inhibits hypoxia- and moderately-high glucose-induced proliferation and VEGF expression in human retinal endothelial cells. Acta Pharmacol Sin 29: 707-712, 2008.
    • (2008) Acta Pharmacol Sin , vol.29 , pp. 707-712
    • Gao, R.1    Zhu, B.H.2    Tang, S.B.3    Wang, J.F.4    Ren, J.5
  • 13
    • 84870060265 scopus 로고    scopus 로고
    • Mannich bases of scutellarein as thrombin-inhibitors: Design synthesis biological activity and solubility
    • Li NG, Song SL, Shen MZ, Tang YP, Shi ZH, Tang H, Shi QP, Fu YF and Duan JA: Mannich bases of scutellarein as thrombin-inhibitors: design, synthesis, biological activity and solubility. Bioorgan Med Chem 20: 6919-6923, 2012.
    • (2012) Bioorgan Med Chem , vol.20 , pp. 6919-6923
    • Li, N.G.1    Song, S.L.2    Shen, M.Z.3    Tang, Y.P.4    Zh, S.5    Tang, H.6    Shi, Q.P.7    Fu, Y.F.8    Duan, J.A.9
  • 14
    • 27644445236 scopus 로고    scopus 로고
    • Inhibitory effects of a chemically standardized extract from Scutellaria barbata in human colon cancer cell lines, LoVo
    • Goh D, Lee YH and Ong ES: Inhibitory effects of a chemically standardized extract from Scutellaria barbata in human colon cancer cell lines, LoVo. J Agr Food Chem 53: 8197-8204, 2005.
    • (2005) J Agr Food Chem , vol.53 , pp. 8197-8204
    • Goh, D.1    Lee, Y.H.2    Ong, E.S.3
  • 17
    • 26444605834 scopus 로고    scopus 로고
    • IKK/NF-kappaB signaling: Balancing life and death - A new approach to cancer therapy
    • Luo JL, Kamata H and Karin M: IKK/NF-kappaB signaling: balancing life and death - a new approach to cancer therapy. J Clin Invest 115: 2625-2632, 2005.
    • (2005) J Clin Invest , vol.115 , pp. 2625-2632
    • Luo, J.L.1    Kamata, H.2    Karin, M.3
  • 18
    • 52049109838 scopus 로고    scopus 로고
    • Natural products in drug discovery
    • Harvey AL: Natural products in drug discovery. Drug Discov Today 13: 894-901, 2008.
    • (2008) Drug Discov Today , vol.13 , pp. 894-901
    • Harvey, A.L.1
  • 19
    • 14944383798 scopus 로고    scopus 로고
    • The evolving role of natural products in drug discovery
    • Koehn FE and Carter GT: The evolving role of natural products in drug discovery. Nat Rev Drug Discov 4: 206-220, 2005.
    • (2005) Nat Rev Drug Discov , vol.4 , pp. 206-220
    • Koehn, F.E.1    Carter, G.T.2
  • 21
    • 68549130601 scopus 로고    scopus 로고
    • Scutellarin sensitizes drug-evoked colon cancer cell apoptosis through enhanced caspase-6 activation
    • Chan JY, Tan BK and Lee SC: Scutellarin sensitizes drug-evoked colon cancer cell apoptosis through enhanced caspase-6 activation. Anticancer Res 29: 3043-3047, 2009.
    • (2009) Anticancer Res , vol.29 , pp. 3043-3047
    • Chan, J.Y.1    Tan, B.K.2    Lee, S.C.3
  • 22
    • 78149328322 scopus 로고    scopus 로고
    • Scutellarin inhibits cell migration by regulating production of αvβ6 integrin and E-cadherin in human tongue cancer cells
    • Li H, Huang D, Gao Z, Lv Y, Zhang L, Cui H and Zheng J: Scutellarin inhibits cell migration by regulating production of αvβ6 integrin and E-cadherin in human tongue cancer cells. Oncol Rep 24: 1153-1160, 2010.
    • (2010) Oncol Rep , vol.24 , pp. 1153-1160
    • Li, H.1    Huang, D.2    Gao, Z.3    Lv, Y.4    Zhang, L.5    Cui, H.6    Zheng, J.7
  • 23
    • 82255184195 scopus 로고    scopus 로고
    • Synthesis and bio-activity evaluation of scutellarein as a potent agent for the therapy of ischemic cerebrovascular disease
    • Qian LH, Li NG, Tang YP, Zhang L, Tang H, Wang ZJ, Liu L, Song SL, Guo JM and Ding AW: Synthesis and bio-activity evaluation of scutellarein as a potent agent for the therapy of ischemic cerebrovascular disease. Int J Mol Sci 12: 8208-8216, 2011.
    • (2011) Int J Mol Sci , vol.12 , pp. 8208-8216
    • Qian, L.H.1    Li, N.G.2    Tang, Y.P.3    Zhang, L.4    Tang, H.5    Wang, Z.J.6    Liu, L.7    Song, S.L.8    Guo, J.M.9    Ding, A.W.10
  • 24
    • 79953147370 scopus 로고    scopus 로고
    • A perspective on cancer cell metastasis
    • Chaffer CL and Weinberg RA: A perspective on cancer cell metastasis. Science 331: 1559-1564, 2011.
    • (2011) Science , vol.331 , pp. 1559-1564
    • Chaffer, C.L.1    Weinberg, R.A.2
  • 26
    • 0038481970 scopus 로고    scopus 로고
    • Timeline - The pathogenesis of cancer metastasis: The 'seed and soil' hypothesis revisited
    • Fidler IJ: Timeline - the pathogenesis of cancer metastasis: the 'seed and soil' hypothesis revisited. Nat Rev Cancer 3: 453-458, 2003.
    • (2003) Nat Rev Cancer , vol.3 , pp. 453-458
    • Fidler, I.J.1
  • 27
    • 34248594553 scopus 로고    scopus 로고
    • Metastasis: Recent discoveries and novel treatment strategies
    • Eccles SA and Welch DR: Metastasis: recent discoveries and novel treatment strategies. Lancet 369: 1742-1757, 2007.
    • (2007) Lancet , vol.369 , pp. 1742-1757
    • Eccles, S.A.1    Welch, D.R.2
  • 29
    • 0037192458 scopus 로고    scopus 로고
    • Matrix metalloproteinase inhibitors and cancer: Trials and tribulations
    • Coussens LM, Fingleton B and Matrisian LM: Matrix metalloproteinase inhibitors and cancer: trials and tribulations. Science 295: 2387-2392, 2002.
    • (2002) Science , vol.295 , pp. 2387-2392
    • Coussens, L.M.1    Fingleton, B.2    Matrisian, L.M.3
  • 30
    • 77950931419 scopus 로고    scopus 로고
    • Matrix metalloproteinases: Regulators of the tumor microenvironment
    • Kessenbrock K, Plaks V and Werb Z: Matrix metalloproteinases: regulators of the tumor microenvironment. Cell 141: 52-67, 2010.
    • (2010) Cell , vol.141 , pp. 52-67
    • Kessenbrock, K.1    Plaks, V.2    Werb, Z.3
  • 31
    • 84856213846 scopus 로고    scopus 로고
    • The diverse and complex roles of NF-κB subunits in cancer
    • Perkins ND: The diverse and complex roles of NF-κB subunits in cancer. Nat Rev Cancer 12: 121-132, 2012.
    • (2012) Nat Rev Cancer , vol.12 , pp. 121-132
    • Perkins, N.D.1
  • 32
    • 0036020941 scopus 로고    scopus 로고
    • NF-κB as a therapeutic target in cancer
    • Orlowski RZ and Baldwin AS: NF-κB as a therapeutic target in cancer. Trends Mol Med 8: 385-389, 2002.
    • (2002) Trends Mol Med , vol.8 , pp. 385-389
    • Orlowski, R.Z.1    Baldwin, A.S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.