Synthesis and bio-activity evaluation of scutellarein as a potent agent for the therapy of ischemic cerebrovascular disease

International Journal of Molecular Sciences

Volumn 12, Issue 11, 2011, Pages 8208-8216

  Qian, Li Hua ^a   Li, Nian Guang ^a   Tang, Yu Ping ^a   Zhang, Li ^a   Tang, Hao ^a   Wang, Zhen Jiang ^a   Liu, Li ^a   Song, Shu Lin ^a   Guo, Jian Ming ^a   Ding, An Wei ^a  

^a NANJING UNIVERSITY OF CHINESE MEDICINE   (China)

Author keywords

Antioxidant activity; Ischemic cerebrovascular disease; Scutellarein; Scutellarin; Synthesis

Indexed keywords

1,1 DIPHENYL 2 PICRYLHYDRAZYL; 2,2' AZINOBIS(3 ETHYLBENZOTHIAZOLINE 6 SULFONIC ACID); ALCOHOL; ASCORBIC ACID; HYDROGEN PEROXIDE; HYDROXYL RADICAL; NITROGEN; SCUTELLAREIN; SCUTELLARIN; SULFURIC ACID; 2,2'-AZINO-DI-(3-ETHYLBENZOTHIAZOLINE)-6-SULFONIC ACID; 2,2-DIPHENYL-1-PICRYLHYDRAZYL; APIGENIN; BENZOTHIAZOLE DERIVATIVE; BIPHENYL DERIVATIVE; GLUCURONIC ACID; PICRIC ACID; SCAVENGER; SULFONIC ACID DERIVATIVE;

ANTIOXIDANT ACTIVITY; ARTICLE; BRAIN ISCHEMIA; CELL ASSAY; CELL PROTECTION; CELL SURVIVAL; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; DRUG ACTIVITY; DRUG EFFICACY; DRUG HYDROLYSIS; DRUG POTENCY; DRUG RESEARCH; DRUG STRUCTURE; DRUG SYNTHESIS; IC 50; IN VITRO STUDY; INCUBATION TIME; OXIDATIVE STRESS; REACTION ANALYSIS; ANIMAL; CEREBROVASCULAR DISORDERS; DRUG EFFECTS; ISCHEMIA; METABOLISM; PC12 CELL LINE; RAT;

ANIMALS; APIGENIN; BENZOTHIAZOLES; BIPHENYL COMPOUNDS; CELL SURVIVAL; CEREBROVASCULAR DISORDERS; FREE RADICAL SCAVENGERS; GLUCURONATES; HYDROGEN PEROXIDE; ISCHEMIA; PC12 CELLS; PICRATES; RATS; SULFONIC ACIDS;

EID: 82255184195     PISSN: None     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms12118208     Document Type: Article

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