Receptor for advanced glycation end products-membrane type1 matrix metalloproteinase axis regulates tissue factor expression via rhoa and rac1 activation in high-mobility group box-1 stimulated endothelial cells

PLoS ONE

Volumn 9, Issue 12, 2014, Pages

  Sugimoto, Koichi ^a   Ohkawara, Hiroshi ^a   Nakamura, Yuichi ^a   Takuwa, Yoh ^b   Ishibashi, Toshiyuki ^c   Takeishi, Yasuchika ^a  

^a FUKUSHIMA MEDICAL UNIVERSITY   (Japan)

^b KANAZAWA UNIVERSITY GRADUATE SCHOOL OF MEDICAL SCIENCE   (Japan)

^c Ohara General Hospital   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ADVANCED GLYCATION END PRODUCT RECEPTOR; HIGH MOBILITY GROUP B1 PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MEMBRANE TYPE1 MATRIX METALLOPROTEASE; METALLOPROTEINASE; RAC1 PROTEIN; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; SMALL INTERFERING RNA; THROMBOPLASTIN; UNCLASSIFIED DRUG; IMMUNOGLOBULIN RECEPTOR; MATRIX METALLOPROTEINASE 14;

AORTA; ARTICLE; ATHEROSCLEROSIS; CELL STIMULATION; CONTROLLED STUDY; ENDOTHELIAL DYSFUNCTION; ENDOTHELIUM CELL; ENZYME ACTIVITY; HUMAN; HUMAN CELL; INTRACELLULAR SIGNALING; MOLECULAR PATHOLOGY; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; UPREGULATION; WESTERN BLOTTING; CYTOLOGY; DEFICIENCY; DRUG EFFECTS; ENZYME ACTIVATION; GENE EXPRESSION REGULATION; GENE SILENCING; GENETICS; METABOLISM; PATHOLOGY; PHOSPHORYLATION;

ADVANCED GLYCOSYLATION END PRODUCT-SPECIFIC RECEPTOR; ATHEROSCLEROSIS; ENDOTHELIAL CELLS; ENZYME ACTIVATION; GENE EXPRESSION REGULATION; GENE SILENCING; HMGB1 PROTEIN; HUMANS; MATRIX METALLOPROTEINASE 14; NF-KAPPA B; PHOSPHORYLATION; RAC1 GTP-BINDING PROTEIN; RECEPTORS, IMMUNOLOGIC; RHOA GTP-BINDING PROTEIN; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; THROMBOPLASTIN;

EID: 84916625508     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0114429     Document Type: Article

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