Thrombin-induced rapid geranylgeranylation of RhoA as an essential process for RhoA activation in endothelial cells

Journal of Biological Chemistry

Volumn 280, Issue 11, 2005, Pages 10182-10188

  Ohkawara, Hiroshi ^a   Ishibashi, Toshiyuki ^a   Sakamoto, Takayuki ^a   Sugimoto, Koichi ^a   Nagata, Kenji ^a   Yokoyama, Keiko ^a   Sakamoto, Nobuo ^a   Kamioka, Masashi ^a   Matsuoka, Isao ^a   Fukuhara, Shigetomo ^b   Sugimoto, Naotoshi ^c   Takuwa, Yoh ^c   Maruyama, Yukio ^a  

^a FUKUSHIMA MEDICAL UNIVERSITY   (Japan)

^b NATIONAL CEREBRAL AND CARDIOVASCULAR CENTER   (Japan)

^c KANAZAWA UNIVERSITY GRADUATE SCHOOL OF MEDICAL SCIENCE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; CHEMICAL ACTIVATION; CHEMICAL MODIFICATION; ENZYME INHIBITION; LIPIDS; MOLECULAR BIOLOGY;

CYTOSKELETON ANALYSIS; ENDOTHELIAL CELLS (EC); GERANYLGERANYLATION; THROMBIN;

CELLS;

ACTIN; ATORVASTATIN; GERANYLGERANYL PYROPHOSPHATE; GERANYLGERANYLTRANSFERASE I; GGTI 286; GUANOSINE TRIPHOSPHATE; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; THROMBIN; TRANSFERASE; TRANSFERASE INHIBITOR; TRITON X 114; UNCLASSIFIED DRUG;

AORTA; ARTICLE; CELL CULTURE; CONTROLLED STUDY; DENSITOMETRY; ENDOTHELIUM CELL; ENZYME ACTIVITY; HUMAN; HUMAN CELL; PARTITION CHROMATOGRAPHY; PRIORITY JOURNAL; PROTEIN PROCESSING; STRESS FIBER; WESTERN BLOTTING;

ACTINS; AORTA; BLOTTING, WESTERN; CELLS, CULTURED; CYTOSKELETON; DENSITOMETRY; DETERGENTS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIAL CELLS; ENDOTHELIUM, VASCULAR; GUANOSINE DIPHOSPHATE; GUANOSINE TRIPHOSPHATE; HEPTANOIC ACIDS; HUMANS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; LEUCINE; LIPID METABOLISM; POLYETHYLENE GLYCOLS; PROTEIN ISOPRENYLATION; PYRROLES; RHOA GTP-BINDING PROTEIN; SIGNAL TRANSDUCTION; THROMBIN; TIME FACTORS;

EID: 20144370412     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M409547200     Document Type: Article

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