Crucial role of membrane type 1 Matrix Metalloproteinase (MT1- MMP) in RhoA/Rac1-dependent signaling Pathways in Thrombin- stimulated endothelial cells

Journal of Atherosclerosis and Thrombosis

Volumn 18, Issue 9, 2011, Pages 762-773

  Ando, Katsuya ^a   Ishibashi, Toshiyuki ^a,b,f   Ohkawara, Hiroshi ^a   Inoue, Nobutaka ^c   Sugimoto, Koichi ^a   Uekita, Hironori ^a   Hu, Chengjun ^d   Okamoto, Yasuo ^e   Takuwa, Yoh ^e   Takeishi, Yasuchika ^a  

^a FUKUSHIMA MEDICAL UNIVERSITY   (Japan)

^b Ohara General Hospital Medical Center   (Japan)

^c KOBE ROSAI HOSPITAL   (Japan)

^d WUHAN UNIVERSITY   (China)

^e KANAZAWA UNIVERSITY GRADUATE SCHOOL OF MEDICAL SCIENCE   (Japan)

^f Ohara Medical Center Hospital   (Japan)

Author keywords

Calcium; Endothelial dysfunction; Molecular expression; NADPH oxidase; Thrombin

Indexed keywords

ADENOVIRUS VECTOR; CALCIUM; EXOENZYME C3; FURA 2; LUCIGENIN; MATRIX METALLOPROTEINASE 14; PLASMINOGEN ACTIVATOR INHIBITOR 1; PROTEIN INHIBITOR; RAC1 PROTEIN; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; SMALL INTERFERING RNA; THROMBIN; THROMBOPLASTIN;

AORTA; ARTICLE; CALCIUM CELL LEVEL; CALCIUM SIGNALING; CELL CULTURE; CELL STIMULATION; CHEMOLUMINESCENCE; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME ACTIVATION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN PROCESSING; VIRAL GENE DELIVERY SYSTEM;

ADENOVIRIDAE; BASE SEQUENCE; CALCIUM; CELLS, CULTURED; ENDOTHELIUM, VASCULAR; GENE SILENCING; HUMANS; LUMINESCENCE; MATRIX METALLOPROTEINASE 14; NADPH OXIDASE; RAC1 GTP-BINDING PROTEIN; REACTIVE OXYGEN SPECIES; RHOA GTP-BINDING PROTEIN; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; THROMBIN; TRANSFECTION;

EID: 80053189515     PISSN: 13403478     EISSN: 18803873     Source Type: Journal    
DOI: 10.5551/jat.6783     Document Type: Article

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