An RNA binding protein promotes axonal integrity in peripheral neurons by destabilizing REST

Journal of Neuroscience

Volumn 34, Issue 50, 2014, Pages 16650-16661

  Cargnin, Francesca ^a   Nechiporuk, Tamilla ^a   Müllendorff, Karin ^a   Stumpo, Deborah J ^b   Blackshear, Perry J ^b   Ballas, Nurit ^c   Mandel, Gail ^a  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^b NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^c STONY BROOK UNIVERSITY   (United States)

Author keywords

Axonal integrity; Peripheral nervous system; Post transcriptional regulation; REST; RNA binding protein; ZFP36L2

Indexed keywords

LENTIVIRUS VECTOR; NERVE GROWTH FACTOR; PENICILLIN G; RE1 SILENCING TRANSCRIPTION FACTOR; RNA BINDING PROTEIN; SHORT HAIRPIN RNA; STREPTOMYCIN SULFATE; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; ZFP36L2; RE1-SILENCING TRANSCRIPTION FACTOR; REPRESSOR PROTEIN; TRISTETRAPROLIN; ZFP36 PROTEIN, MOUSE;

3' UNTRANSLATED REGION; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; AXONAL INTEGRITY; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DIAGNOSIS RELATED GROUP; FEMALE; FEMALE FERTILITY; GEL MOBILITY SHIFT ASSAY; GENE EXPRESSION; GENE SEQUENCE; GENETIC TRANSFECTION; HEK293 CELL LINE; HEMATOPOIESIS; HUMAN; IMMUNOFLUORESCENCE; IMMUNOFLUORESCENCE TEST; IMMUNOHISTOCHEMISTRY; MALE; MOUSE; NERVE CELL CHARACTERISTICS AND FUNCTIONS; NONHUMAN; PHENOTYPE; PHYSICAL PARAMETERS; PROTEIN ANALYSIS; RAT; REAL TIME POLYMERASE CHAIN REACTION; RNA ISOLATION; RNA STABILITY; SCIATIC NERVE; SPINAL GANGLION; SUPERIOR CERVICAL GANGLION; TRANSCRIPTION REGULATION; WESTERN BLOTTING; ANIMAL; BIOSYNTHESIS; CELL CULTURE; GENETICS; KNOCKOUT MOUSE; METABOLISM; NERVE FIBER; PC12 CELL LINE;

ANIMALS; AXONS; CELLS, CULTURED; FEMALE; GANGLIA, SPINAL; MALE; MICE; MICE, KNOCKOUT; PC12 CELLS; RATS; REPRESSOR PROTEINS; RNA-BINDING PROTEINS; TRISTETRAPROLIN;

EID: 84916620401     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.1650-14.2014     Document Type: Article

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