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Volumn 42, Issue 1, 2014, Pages 143-155

Modulation of Neuronal Nicotinic Receptor by Quinolizidine Alkaloids Causes Neuroprotection on a Cellular Alzheimer Model

Author keywords

Alkaloids; Alzheimer's disease; neuroprotection; nicotinic receptor; Teline monspessulana

Indexed keywords

ALKALOID; AMYLOID BETA PROTEIN; ATROPINE; BOTULINUM TOXIN A; NEUROPROTECTIVE AGENT; NICOTINIC RECEPTOR; PHOSPHATIDYLINOSITOL 3 KINASE; PLANT EXTRACT; PROTEIN BCL 2; PROTEIN KINASE B; QUINOLIZIDINE DERIVATIVE; TELINE MONSPESSULANA EXTRACT; UNCLASSIFIED DRUG; AMYLOID BETA PROTEIN[1-40]; PEPTIDE FRAGMENT;

EID: 84916595109     PISSN: 13872877     EISSN: 18758908     Source Type: Journal    
DOI: 10.3233/JAD-132045     Document Type: Article
Times cited : (21)

References (49)
  • 1
    • 0027312981 scopus 로고
    • Neuropsychological patterns and language deficits in 20 consecutive cases of autopsy-confirmed Alzheimer's disease
    • Price BH, Gurvit H, Weintraub S, Geula C, Leimkuhler E, Mesulam M (1993) Neuropsychological patterns and language deficits in 20 consecutive cases of autopsy-confirmed Alzheimer's disease. Arch Neurol 50, 931-937.
    • (1993) Arch Neurol , vol.50 , pp. 931-937
    • Price, B.H.1    Gurvit, H.2    Weintraub, S.3    Geula, C.4    Leimkuhler, E.5    Mesulam, M.6
  • 2
    • 57649148788 scopus 로고    scopus 로고
    • Structural classification of toxic amyloid oligomers
    • Glabe CG (2008) Structural classification of toxic amyloid oligomers. J Biol Chem 283, 29639-29643.
    • (2008) J Biol Chem , vol.283 , pp. 29639-29643
    • Glabe, C.G.1
  • 6
    • 79955665348 scopus 로고    scopus 로고
    • Aberrant subcellular neuronal calcium regulation in aging and Alzheimer's disease
    • Camandola S, Mattson MP (2010) Aberrant subcellular neuronal calcium regulation in aging and Alzheimer's disease. Biochim Biophys Acta 1813, 965-973.
    • (2010) Biochim Biophys Acta , vol.1813 , pp. 965-973
    • Camandola, S.1    Mattson, M.P.2
  • 7
    • 50249135503 scopus 로고    scopus 로고
    • Neuronal calcium mishandling and the pathogenesis of Alzheimer's disease
    • Bezprozvanny I, Mattson MP (2008) Neuronal calcium mishandling and the pathogenesis of Alzheimer's disease. Trends Neurosci 31, 454-463.
    • (2008) Trends Neurosci , vol.31 , pp. 454-463
    • Bezprozvanny, I.1    Mattson, M.P.2
  • 8
    • 0034125843 scopus 로고    scopus 로고
    • Onneurodegenerative diseases, models, and treatment strategies: Lessons learned and lessons forgotten a generation following the cholinergic hypothesis
    • Bartus RT(2000)Onneurodegenerative diseases, models, and treatment strategies: Lessons learned and lessons forgotten a generation following the cholinergic hypothesis. Exp Neurol 163, 495-529.
    • (2000) Exp Neurol , vol.163 , pp. 495-529
    • Bartus, R.T.1
  • 9
    • 79954582437 scopus 로고    scopus 로고
    • Revisiting the cholinergic hypothesis in the development of Alzheimer's disease
    • Craig LA, Hong NS, McDonald RJ (2011) Revisiting the cholinergic hypothesis in the development of Alzheimer's disease. Neurosci Biobehav Rev 35, 1397-1409.
    • (2011) Neurosci Biobehav Rev , vol.35 , pp. 1397-1409
    • Craig, L.A.1    Hong, N.S.2    McDonald, R.J.3
  • 10
    • 0036736218 scopus 로고    scopus 로고
    • Amyloid precursor protein, presenilins, and α-synuclein: Molecular pathogenesis and pharmacological applications in Alzheimer's disease
    • Suh Y- H, Checler F (2002) Amyloid precursor protein, presenilins, and α-synuclein: Molecular pathogenesis and pharmacological applications in Alzheimer's disease. Pharmacol Rev 54, 469-525.
    • (2002) Pharmacol Rev , vol.54 , pp. 469-525
    • Suh, Y.-H.1    Checler, F.2
  • 11
    • 79955671904 scopus 로고    scopus 로고
    • Stimulating nicotinic receptors trigger multiple pathways attenuating cytotoxicity in models of Alzheimer's and Parkinson's diseases
    • Kawamata J, Shimohama S (2011) Stimulating nicotinic receptors trigger multiple pathways attenuating cytotoxicity in models of Alzheimer's and Parkinson's diseases. J Alzheimers Dis 24, 95-109.
    • (2011) J Alzheimers Dis , vol.24 , pp. 95-109
    • Kawamata, J.1    Shimohama, S.2
  • 12
    • 0034594469 scopus 로고    scopus 로고
    • Choline acetyltransferase activity and cognitive domain scores of Alzheimer's patients
    • Pappas BA, Bayley PJ, Bui BK, Hansen LA, Thal LJ (2000) Choline acetyltransferase activity and cognitive domain scores of Alzheimer's patients. Neurobiol Aging 21, 11-17.
    • (2000) Neurobiol Aging , vol.21 , pp. 11-17
    • Pappas, B.A.1    Bayley, P.J.2    Bui, B.K.3    Hansen, L.A.4    Thal, L.J.5
  • 13
    • 0018078940 scopus 로고
    • Correlation of cholinergic abnormalities with senile plaques and mental test scores in senile dementia
    • Perry EK, Tomlinson BE, Blessed G, Bergmann K, Gibson PH, Perry RH(1978) Correlation of cholinergic abnormalities with senile plaques and mental test scores in senile dementia. BMJ 2, 1457-1459.
    • (1978) BMJ , vol.2 , pp. 1457-1459
    • Perry, E.K.1    Tomlinson, B.E.2    Blessed, G.3    Bergmann, K.4    Gibson, P.H.5    Perry, R.H.6
  • 14
    • 0242486453 scopus 로고    scopus 로고
    • Protein and mRNA levels of nicotinic receptors in brain of tobacco using controls and patients with Alzheimer's disease
    • Mousavi M, Hellström-Lindahl E, Guan ZZ, Shan KR, Ravid R, Nordberg A (2003) Protein and mRNA levels of nicotinic receptors in brain of tobacco using controls and patients with Alzheimer's disease. Neuroscience 122, 515-520.
    • (2003) Neuroscience , vol.122 , pp. 515-520
    • Mousavi, M.1    Hellström-Lindahl, E.2    Guan, Z.Z.3    Shan, K.R.4    Ravid, R.5    Nordberg, A.6
  • 15
    • 0037083689 scopus 로고    scopus 로고
    • Nicotine increases the expression of high affinity nerve growth factor receptors in both in vitro and in vivo
    • Jonnala RR, Terry AV, Jr., Buccafusco JJ (2002) Nicotine increases the expression of high affinity nerve growth factor receptors in both in vitro and in vivo. Life Sci 70, 1543-1554.
    • (2002) Life Sci , vol.70 , pp. 1543-1554
    • Jonnala, R.R.1    Terry, A.V.2    Buccafusco, J.J.3
  • 16
    • 27644540190 scopus 로고    scopus 로고
    • Effect of amyloid peptides on the increase in TrkA receptor expression induced by nicotine in vitro and in vivo
    • Li X, Arias E, Jonnala R, Mruthinti S, Buccafusco J (2005) Effect of amyloid peptides on the increase in TrkA receptor expression induced by nicotine in vitro and in vivo. J Mol Neurosci 27, 325-336.
    • (2005) J Mol Neurosci , vol.27 , pp. 325-336
    • Li, X.1    Arias, E.2    Jonnala, R.3    Mruthinti, S.4    Buccafusco, J.5
  • 18
    • 0035957946 scopus 로고    scopus 로고
    • α7 nicotinic receptor transduces signals to phosphatidylinositol 3-kinase to block Aβ-amyloid-induced neurotoxicity
    • Kihara T, Shimohama S, Sawada H, Honda K, Nakamizo T, Shibasaki H, Kume T, Akaike A (2001) α7 nicotinic receptor transduces signals to phosphatidylinositol 3-kinase to block Aβ-amyloid-induced neurotoxicity. J Biol Chem 276, 13541-13546.
    • (2001) J Biol Chem , vol.276 , pp. 13541-13546
    • Kihara, T.1    Shimohama, S.2    Sawada, H.3    Honda, K.4    Nakamizo, T.5    Shibasaki, H.6    Kume, T.7    Akaike, A.8
  • 19
    • 80054811612 scopus 로고    scopus 로고
    • α7 Nicotinic receptor activation reduces β-amyloid-induced apoptosis by inhibiting caspase-independent death through phosphatidylinositol 3-kinase signaling
    • Yu W, Mechawar N, Krantic S, Quirion R (2011) α7 Nicotinic receptor activation reduces β-amyloid-induced apoptosis by inhibiting caspase-independent death through phosphatidylinositol 3-kinase signaling. J Neurochem 119, 848-858.
    • (2011) J Neurochem , vol.119 , pp. 848-858
    • Yu, W.1    Mechawar, N.2    Krantic, S.3    Quirion, R.4
  • 20
    • 75049085215 scopus 로고    scopus 로고
    • Mechanisms of neuroprotective effects of nicotine and acetylcholinesterase inhibitors: Role of α4 and α7 receptors in neuroprotection
    • Akaike A, Takada-Takatori Y, Kume T, Izumi Y (2010) Mechanisms of neuroprotective effects of nicotine and acetylcholinesterase inhibitors: Role of α4 and α7 receptors in neuroprotection. J Mol Neurosci 40, 211-216.
    • (2010) J Mol Neurosci , vol.40 , pp. 211-216
    • Akaike, A.1    Takada-Takatori, Y.2    Kume, T.3    Izumi, Y.4
  • 21
    • 23944472732 scopus 로고    scopus 로고
    • Nicotinic agonists, antagonists, and modulators from natural sources
    • Daly JW (2005) Nicotinic agonists, antagonists, and modulators from natural sources. Cell Mol Neurobiol 25, 513-552.
    • (2005) Cell Mol Neurobiol , vol.25 , pp. 513-552
    • Daly, J.W.1
  • 23
    • 0014446583 scopus 로고
    • Some studies on cytisine and its methylated derivatives
    • Barlow RB, McLeod LJ (1969) Some studies on cytisine and its methylated derivatives. Br J Pharmacol 35, 161-174.
    • (1969) Br J Pharmacol , vol.35 , pp. 161-174
    • Barlow, R.B.1    McLeod, L.J.2
  • 24
    • 16244414874 scopus 로고    scopus 로고
    • Halogenated and isosteric cytisine derivatives with increased affinity and functional activity at nicotinic acetylcholine receptors
    • Fitch RW, Kaneko Y, Klaperski P, Daly JW, Seitz G, Gündisch D (2005) Halogenated and isosteric cytisine derivatives with increased affinity and functional activity at nicotinic acetylcholine receptors. Bioorg Med Chem Lett 15, 1221-1224.
    • (2005) Bioorg Med Chem Lett , vol.15 , pp. 1221-1224
    • Fitch, R.W.1    Kaneko, Y.2    Klaperski, P.3    Daly, J.W.4    Seitz, G.5    Gündisch, D.6
  • 27
    • 77449122733 scopus 로고    scopus 로고
    • Beta-amyloid causes depletion of synaptic vesicles leading to neurotransmission failure
    • Parodi J, Sepulveda FJ, Roa J, Opazo C, Inestrosa NC, Aguayo LG(2010) Beta-amyloid causes depletion of synaptic vesicles leading to neurotransmission failure. J Biol Chem 285, 2506-2514.
    • (2010) J Biol Chem , vol.285 , pp. 2506-2514
    • Parodi, J.1    Sepulveda, F.J.2    Roa, J.3    Opazo, C.4    Inestrosa, N.C.5    Aguayo, L.G.6
  • 28
    • 77955701756 scopus 로고    scopus 로고
    • Synaptotoxicity of Alzheimer beta amyloid can be explained by its membrane perforating property
    • Sepulveda FJ, Parodi J, Peoples RW, Opazo C, Aguayo LG (2010) Synaptotoxicity of Alzheimer beta amyloid can be explained by its membrane perforating property. PLoS One 5, e11820.
    • (2010) PLoS One , vol.5
    • Sepulveda, F.J.1    Parodi, J.2    Peoples, R.W.3    Opazo, C.4    Aguayo, L.G.5
  • 29
    • 36549064191 scopus 로고    scopus 로고
    • Bcl-2 overexpression protects against amyloid-beta and prion toxicity in GT1-7 neural cells
    • Ferreiro E, Eufrasio A, Pereira C, Oliveira CR, Rego AC (2007) Bcl-2 overexpression protects against amyloid-beta and prion toxicity in GT1-7 neural cells. J Alzheimers Dis 12, 223-228.
    • (2007) J Alzheimers Dis , vol.12 , pp. 223-228
    • Ferreiro, E.1    Eufrasio, A.2    Pereira, C.3    Oliveira, C.R.4    Rego, A.C.5
  • 31
    • 84862809685 scopus 로고    scopus 로고
    • The protective effect of sonic hedgehog is mediated by the propidium iodide 3- kinase/AKT/BCL-2 pathway in cultured rat astrocytes under oxidative stress
    • Xia YP, Dai RL, Li YN, Mao L, Xue YM, He QW, Huang M, Huang Y, Mei YW, Hu B (2012) The protective effect of sonic hedgehog is mediated by the propidium iodide 3- kinase/AKT/BCL-2 pathway in cultured rat astrocytes under oxidative stress. Neuroscience 209, 1-11.
    • (2012) Neuroscience , vol.209 , pp. 1-11
    • Xia, Y.P.1    Dai, R.L.2    Li, Y.N.3    Mao, L.4    Xue, Y.M.5    He, Q.W.6    Huang, M.7    Huang, Y.8    Mei, Y.W.9    Hu, B.10
  • 33
    • 84873672674 scopus 로고    scopus 로고
    • Perspectives on kiss-and-run: Role in exocytosis, endocytosis, and neurotransmission
    • Alabi AA, Tsien RW (2013) Perspectives on kiss-and-run: Role in exocytosis, endocytosis, and neurotransmission. Ann Rev Physiol 75, 393-422.
    • (2013) Ann Rev Physiol , vol.75 , pp. 393-422
    • Alabi, A.A.1    Tsien, R.W.2
  • 34
    • 77449122733 scopus 로고    scopus 로고
    • Beta-amyloid causes depletion of synaptic vesicles leading to neurotransmission failure
    • Parodi J, Sepúlveda FJ, Roa J, Opazo C, Inestrosa NC, Aguayo LG(2010) Beta-amyloid causes depletion of synaptic vesicles leading to neurotransmission failure. J Biol Chem 285, 2506-2514.
    • (2010) J Biol Chem , vol.285 , pp. 2506-2514
    • Parodi, J.1    Sepúlveda, F.J.2    Roa, J.3    Opazo, C.4    Inestrosa, N.C.5    Aguayo, L.G.6
  • 35
    • 77955701756 scopus 로고    scopus 로고
    • Synaptotoxicity of Alzheimer beta amyloid can be explained by its membrane perforating property
    • Sepulveda FJ, Parodi J, Peoples RW, Opazo C, Aguayo LG (2010) Synaptotoxicity of Alzheimer beta amyloid can be explained by its membrane perforating property. PLoS One 5, e11820.
    • (2010) PLoS One , vol.5
    • Sepulveda, F.J.1    Parodi, J.2    Peoples, R.W.3    Opazo, C.4    Aguayo, L.G.5
  • 36
    • 0036644989 scopus 로고    scopus 로고
    • Reversal of amyloid β toxicity in Alzheimer's disease model Tg2576 by intraventricular antiamyloid β antibody
    • Chauhan NB, Siegel GJ (2002) Reversal of amyloid β toxicity in Alzheimer's disease model Tg2576 by intraventricular antiamyloid β antibody. J Neurosci Res 69, 10-23.
    • (2002) J Neurosci Res , vol.69 , pp. 10-23
    • Chauhan, N.B.1    Siegel, G.J.2
  • 38
    • 0029658739 scopus 로고    scopus 로고
    • Human α4β2 neuronal nicotinic acetylcholine receptor in HEK 293 cells: A patch-clamp study
    • Buisson B, Gopalakrishnan M, Arneric SP, Sullivan JP, Bertrand D (1996) Human α4β2 neuronal nicotinic acetylcholine receptor in HEK 293 cells: A patch-clamp study. J Neurosci 16, 7880-7891.
    • (1996) J Neurosci , vol.16 , pp. 7880-7891
    • Buisson, B.1    Gopalakrishnan, M.2    Arneric, S.P.3    Sullivan, J.P.4    Bertrand, D.5
  • 39
    • 14844334141 scopus 로고    scopus 로고
    • Long-term exposure to nicotine, via Ras pathway, induces cyclin D1 to stimulate G1 cell cycle transition
    • Chu M, Guo J, Chen C-Y (2005) Long-term exposure to nicotine, via Ras pathway, induces cyclin D1 to stimulate G1 cell cycle transition. J Biol Chem 280, 6369-6379.
    • (2005) J Biol Chem , vol.280 , pp. 6369-6379
    • Chu, M.1    Guo, J.2    Chen, C.-Y.3
  • 42
    • 0036618178 scopus 로고    scopus 로고
    • Preferential transformation of human neuronal cells by human adenoviruses and the origin of HEK 293 cells
    • Shaw G, Morse S, Ararat M, Graham FL (2002) Preferential transformation of human neuronal cells by human adenoviruses and the origin of HEK 293 cells. FASEB J 16, 869-871.
    • (2002) FASEB J , vol.16 , pp. 869-871
    • Shaw, G.1    Morse, S.2    Ararat, M.3    Graham, F.L.4
  • 43
    • 0030842275 scopus 로고    scopus 로고
    • Potentiation and Inhibition of neuronal nicotinic receptors by atropine: Competitive and noncompetitive effects
    • Zwart R, Vijverberg HPM (1997) Potentiation and Inhibition of neuronal nicotinic receptors by atropine: Competitive and noncompetitive effects. Mol Pharmacol 52, 886-895.
    • (1997) Mol Pharmacol , vol.52 , pp. 886-895
    • Zwart, R.1    Vijverberg, H.P.M.2
  • 45
    • 43849088152 scopus 로고    scopus 로고
    • Abeta(1-42) modulation of Akt phosphorylation via alpha7 nAChR and NMDA receptors
    • Abbott JJ, Howlett DR, Francis PT, Williams RJ (2008) Abeta(1-42) modulation of Akt phosphorylation via alpha7 nAChR and NMDA receptors. Neurobiol Aging 29, 992-1001.
    • (2008) Neurobiol Aging , vol.29 , pp. 992-1001
    • Abbott, J.J.1    Howlett, D.R.2    Francis, P.T.3    Williams, R.J.4
  • 46
    • 28044446528 scopus 로고    scopus 로고
    • Intraneuronal beta-amyloid expression downregulates the Akt survival pathway and blunts the stress response
    • Magrane J, Rosen KM, Smith RC, Walsh K, Gouras GK, Querfurth HW(2005) Intraneuronal beta-amyloid expression downregulates the Akt survival pathway and blunts the stress response. J Neurosci 25, 10960-10969.
    • (2005) J Neurosci , vol.25 , pp. 10960-10969
    • Magrane, J.1    Rosen, K.M.2    Smith, R.C.3    Walsh, K.4    Gouras, G.K.5    Querfurth, H.W.6
  • 47
    • 75049085215 scopus 로고    scopus 로고
    • Mechanisms of neuroprotective effects of nicotine and acetylcholinesterase inhibitors: Role of alpha4 and alpha7 receptors in neuroprotection
    • Akaike A, Takada-Takatori Y, Kume T, Izumi Y (2010) Mechanisms of neuroprotective effects of nicotine and acetylcholinesterase inhibitors: Role of alpha4 and alpha7 receptors in neuroprotection. J Mol Neurosci 40, 211-216.
    • (2010) J Mol Neurosci , vol.40 , pp. 211-216
    • Akaike, A.1    Takada-Takatori, Y.2    Kume, T.3    Izumi, Y.4
  • 48
    • 79955671904 scopus 로고    scopus 로고
    • Stimulating nicotinic receptors trigger multiple pathways attenuating cytotoxicity in models of Alzheimer's and Parkinson's diseases
    • Kawamata J, Shimohama S (2011) Stimulating nicotinic receptors trigger multiple pathways attenuating cytotoxicity in models of Alzheimer's and Parkinson's diseases. J Alzheimers Dis 24(Suppl 2), 95-109.
    • (2011) J Alzheimers Dis , vol.24 , pp. 95-109
    • Kawamata, J.1    Shimohama, S.2
  • 49
    • 0035957946 scopus 로고    scopus 로고
    • Alpha 7 nicotinic receptor transduces signals to phosphatidylinositol 3-kinase to block A beta-amyloid-induced neurotoxicity
    • Kihara T, Shimohama S, Sawada H, Honda K, Nakamizo T, Shibasaki H, Kume T, Akaike A (2001) alpha 7 nicotinic receptor transduces signals to phosphatidylinositol 3-kinase to block A beta-amyloid-induced neurotoxicity. J Biol Chem 276, 13541-13546.
    • (2001) J Biol Chem , vol.276 , pp. 13541-13546
    • Kihara, T.1    Shimohama, S.2    Sawada, H.3    Honda, K.4    Nakamizo, T.5    Shibasaki, H.6    Kume, T.7    Akaike, A.8


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