메뉴 건너뛰기




Volumn , Issue , 2009, Pages 13-21

Pore-forming neurotoxin-like mechanism for Aβ oligomer-induced synaptic failure

Author keywords

[No Author keywords available]

Indexed keywords


EID: 84900042962     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1007/978-0-387-87995-6_2     Document Type: Chapter
Times cited : (7)

References (35)
  • 1
    • 0012510759 scopus 로고
    • Amyloid plaque core protein in Alzheimer disease and Down syndrome
    • Masters CL, Simms G, Weinman NA. et al. (1985) Amyloid plaque core protein in Alzheimer disease and Down syndrome. Proc Natl Acad Sci USA 82: 4245-4249
    • (1985) Proc Natl Acad Sci USA , vol.82 , pp. 4245-4249
    • Masters, C.L.1    Simms, G.2    Weinman, N.A.3
  • 2
    • 33645038471 scopus 로고    scopus 로고
    • A specific amyloid-b protein assembly in the brain impairs memory
    • Lesne S, Koh MT, Kotilinek L. et al. (2006) A specific amyloid-b protein assembly in the brain impairs memory. Nature 440: 352-357
    • (2006) Nature , vol.440 , pp. 352-357
    • Lesne, S.1    Koh, M.T.2    Kotilinek, L.3
  • 3
    • 11544279355 scopus 로고    scopus 로고
    • Diffusible, nonfibrillar ligands derived from A b 1-42 are potent central nervous system neurotoxins
    • Lambert MP, Barlow AK, Chromy BA. et al. (1998) Diffusible, nonfibrillar ligands derived from A b 1-42 are potent central nervous system neurotoxins. Proc Natl Acad Sci USA 95: 6448-6453
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 6448-6453
    • Lambert, M.P.1    Barlow, A.K.2    Chromy, B.A.3
  • 4
    • 0032590054 scopus 로고    scopus 로고
    • Soluble pool of A b amyloid as a determinant of severity of neurodegeneration in Alzheimer's disease
    • McLean CA, Cherny RA, Fraser FW. et al. (1999) Soluble pool of A b amyloid as a determinant of severity of neurodegeneration in Alzheimer's disease. Ann Neurol 46: 860-866
    • (1999) Ann Neurol , vol.46 , pp. 860-866
    • McLean, C.A.1    Cherny, R.A.2    Fraser, F.W.3
  • 5
    • 14944378094 scopus 로고    scopus 로고
    • Certain inhibitors of synthetic amyloid b-peptide (A b) fibrillogenesis block oligomerization of natural A b and thereby rescue long-Term potentiation
    • Walsh DM, Townsend M, Podlisny MB. et al. (2005) Certain inhibitors of synthetic amyloid b-peptide (A b) fibrillogenesis block oligomerization of natural A b and thereby rescue long-Term potentiation. J Neurosci 25: 2455-2462
    • (2005) J Neurosci , vol.25 , pp. 2455-2462
    • Walsh, D.M.1    Townsend, M.2    Podlisny, M.B.3
  • 6
    • 0037130570 scopus 로고    scopus 로고
    • Characterization of neuronal dystrophy induced by fibrillar A b: Implications for Alzheimer's disease
    • Grace EA, Rabiner CA, Busciglio J (2002) Characterization of neuronal dystrophy induced by fibrillar A b: Implications for Alzheimer's disease. Neuroscience 114: 265-273
    • (2002) Neuroscience , vol.114 , pp. 265-273
    • Grace, E.A.1    Rabiner, C.A.2    Busciglio, J.3
  • 7
    • 38949123792 scopus 로고    scopus 로고
    • Rapid appearance and local toxicity of A b plaques in a mouse model of Alzheimer's disease
    • Meyer-Luehmann M, Spires-Jones TL, Prada C. et al. (2008) Rapid appearance and local toxicity of A b plaques in a mouse model of Alzheimer's disease. Nature 451: 720-724
    • (2008) Nature , vol.451 , pp. 720-724
    • Meyer-Luehmann, M.1    Spires-Jones, T.L.2    Prada, C.3
  • 8
    • 0037174618 scopus 로고    scopus 로고
    • Alzheimer's disease is a synaptic failure
    • Selkoe DJ (2002) Alzheimer's disease is a synaptic failure. Science 298: 789-791
    • (2002) Science , vol.298 , pp. 789-791
    • Selkoe, D.J.1
  • 9
    • 24744472049 scopus 로고    scopus 로고
    • A b-induced dynamin 1 depletion in hippocampal neurons. A potential mechanism for early cognitive decline in Alzheimer disease
    • Kelly BL, Vassar R, Ferreira A (2005) A b-induced dynamin 1 depletion in hippocampal neurons. A potential mechanism for early cognitive decline in Alzheimer disease. J Biol Chem 280: 31746-31753
    • (2005) J Biol Chem , vol.280 , pp. 31746-31753
    • Kelly, B.L.1    Vassar, R.2    Ferreira, A.3
  • 10
    • 23044445669 scopus 로고    scopus 로고
    • Regulation of NMDA receptor trafficking by A b
    • Snyder EM, Nong Y, Almeida CG. et al. (2005) Regulation of NMDA receptor trafficking by A b. Nat Neurosci 8: 1051-1058
    • (2005) Nat Neurosci , vol.8 , pp. 1051-1058
    • Snyder, E.M.1    Nong, Y.2    Almeida, C.G.3
  • 11
    • 13044287361 scopus 로고    scopus 로고
    • Plaque-independent disruption of neural circuits in Alzheimer's disease mouse models
    • Hsia AY, Masliah E, McConlogue L. et al. (1999) Plaque-independent disruption of neural circuits in Alzheimer's disease mouse models. Proc Natl Acad Sci USA 96: 3228-3233
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 3228-3233
    • Hsia, A.Y.1    Masliah, E.2    McConlogue, L.3
  • 12
    • 0025987048 scopus 로고
    • Physical basis of cognitive alterations in Alzheimer's disease: Synapse loss is the major correlate of cognitive impairment
    • Terry RD, Masliah E, Salmon DP. et al. (1991) Physical basis of cognitive alterations in Alzheimer's disease: Synapse loss is the major correlate of cognitive impairment. Ann Neurol 30: 572-580
    • (1991) Ann Neurol , vol.30 , pp. 572-580
    • Terry, R.D.1    Masliah, E.2    Salmon, D.P.3
  • 13
    • 0346156091 scopus 로고    scopus 로고
    • Synaptic frailty and clathrin-mediated synaptic vesicle trafficking in Alzheimer's disease
    • Yao PJ (2004) Synaptic frailty and clathrin-mediated synaptic vesicle trafficking in Alzheimer's disease. Trends Neurosci 27: 24-29
    • (2004) Trends Neurosci , vol.27 , pp. 24-29
    • Yao, P.J.1
  • 14
    • 3943092621 scopus 로고    scopus 로고
    • Pathways towards and away from Alzheimer's disease
    • Mattson MP (2004) Pathways towards and away from Alzheimer's disease. Nature 430: 631-639
    • (2004) Nature , vol.430 , pp. 631-639
    • Mattson, M.P.1
  • 15
    • 0033816844 scopus 로고    scopus 로고
    • A b neurotoxicity is mediated by a glutamatetriggered excitotoxic cascade in rat nucleus basalis
    • Harkany T, Abraham I, Timmerman W. et al. (2000) A b neurotoxicity is mediated by a glutamatetriggered excitotoxic cascade in rat nucleus basalis. Eur J Neurosci 12: 2735-2745
    • (2000) Eur J Neurosci , vol.12 , pp. 2735-2745
    • Harkany, T.1    Abraham, I.2    Timmerman, W.3
  • 16
    • 11244317067 scopus 로고    scopus 로고
    • Alzheimer's amyloid peptides mediate hypoxic up-regulation of L-Type Ca 2+ channels
    • Scragg JL, Fearon IM, Boyle JP. et al. (2005) Alzheimer's amyloid peptides mediate hypoxic up-regulation of L-Type Ca 2+ channels. FASEB J 19: 150-152
    • (2005) FASEB J , vol.19 , pp. 150-152
    • Scragg, J.L.1    Fearon, I.M.2    Boyle, J.P.3
  • 17
    • 0035997234 scopus 로고    scopus 로고
    • The channel hypothesis of Alzheimer's disease: Current status
    • Kagan BL, Hirakura Y, Azimov R. et al. (2002) The channel hypothesis of Alzheimer's disease: Current status. Peptides 23: 1311-1315
    • (2002) Peptides , vol.23 , pp. 1311-1315
    • Kagan, B.L.1    Hirakura, Y.2    Azimov, R.3
  • 18
    • 0027944284 scopus 로고
    • Theoretical models of the ion channel structure of A b-protein
    • Durell SR, Guy HR, Arispe N. et al. (1994) Theoretical models of the ion channel structure of A b-protein. Biophys J 67: 2137-2145
    • (1994) Biophys J , vol.67 , pp. 2137-2145
    • Durell, S.R.1    Guy, H.R.2    Arispe, N.3
  • 19
    • 0027508926 scopus 로고
    • Alzheimer disease A b-protein forms calcium channels in bilayer membranes: Blockade by tromethamine and aluminum
    • Arispe N, Rojas E, Pollard HB (1993) Alzheimer disease A b-protein forms calcium channels in bilayer membranes: Blockade by tromethamine and aluminum. Proc Natl Acad Sci USA 90: 567-571
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 567-571
    • Arispe, N.1    Rojas, E.2    Pollard, H.B.3
  • 20
    • 0034640372 scopus 로고    scopus 로고
    • Alzheimer's A b, human islet amylin, and prion protein fragment evoke intracellular free calcium elevations by a common mechanism in a hypothalamic GnRH neuronal cell line
    • Kawahara M, Kuroda Y, Arispe N. et al. (2000) Alzheimer's A b, human islet amylin, and prion protein fragment evoke intracellular free calcium elevations by a common mechanism in a hypothalamic GnRH neuronal cell line. J Biol Chem 275: 14077-14083
    • (2000) J Biol Chem , vol.275 , pp. 14077-14083
    • Kawahara, M.1    Kuroda, Y.2    Arispe, N.3
  • 21
    • 0030966536 scopus 로고    scopus 로고
    • Alzheimer's disease A b-protein forms Zn 2+-sensitive, cation-selective channels across excised membrane patches from hypothalamic neurons
    • Kawahara M, Arispe N, Kuroda Y. et al. (1997) Alzheimer's disease A b-protein forms Zn 2+-sensitive, cation-selective channels across excised membrane patches from hypothalamic neurons. Biophys J 73: 67-75
    • (1997) Biophys J , vol.73 , pp. 67-75
    • Kawahara, M.1    Arispe, N.2    Kuroda, Y.3
  • 22
    • 0027980901 scopus 로고
    • Rapid induction of Alzheimer A b amyloid formation by zinc
    • Bush AI, Pettingell WH, Multhaup G. et al. (1994) Rapid induction of Alzheimer A b amyloid formation by zinc. Science 265: 1464-1467
    • (1994) Science , vol.265 , pp. 1464-1467
    • Bush, A.I.1    Pettingell, W.H.2    Multhaup, G.3
  • 23
    • 0034856924 scopus 로고    scopus 로고
    • Diversity of A b protein fragment [1-40]-formed channels
    • Kourie JI, Henry CL, Farrelly P (2001) Diversity of A b protein fragment [1-40]-formed channels. Cell Mol Neurobiol 21: 255-284
    • (2001) Cell Mol Neurobiol , vol.21 , pp. 255-284
    • Kourie, J.I.1    Henry, C.L.2    Farrelly, P.3
  • 24
    • 8744220663 scopus 로고    scopus 로고
    • Permeabilization of lipid bilayers is a common conformation-dependent activity of soluble amyloid oligomers in protein misfolding diseases
    • Kayed R, Sokolov Y, Edmonds B. et al. (2004) Permeabilization of lipid bilayers is a common conformation-dependent activity of soluble amyloid oligomers in protein misfolding diseases. J Biol Chem 279: 46363-46366
    • (2004) J Biol Chem , vol.279 , pp. 46363-46366
    • Kayed, R.1    Sokolov, Y.2    Edmonds, B.3
  • 25
    • 0038244830 scopus 로고    scopus 로고
    • Nicotinic receptors and Alzheimer's disease
    • Bourin M, Ripoll N, Dailly E (2003) Nicotinic receptors and Alzheimer's disease. Curr Med Res Opin 19: 169-177
    • (2003) Curr Med Res Opin , vol.19 , pp. 169-177
    • Bourin, M.1    Ripoll, N.2    Dailly, E.3
  • 26
    • 0034829801 scopus 로고    scopus 로고
    • The molecular bases of Alzheimer's disease and other neurodegenerative disorders
    • Maccioni RB, Muñoz JP, Barbeito L (2001) The molecular bases of Alzheimer's disease and other neurodegenerative disorders. Arch Med Res 32: 367-381
    • (2001) Arch Med Res , vol.32 , pp. 367-381
    • Maccioni, R.B.1    Muñoz, J.P.2    Barbeito, L.3
  • 27
    • 0033769211 scopus 로고    scopus 로고
    • A-latrotoxin forms calciumpermeable membrane pores via interactions with latrophilin or neurexin
    • Van Renterghem C, Iborra C, Martin-Moutot N. et al. (2000) a-latrotoxin forms calciumpermeable membrane pores via interactions with latrophilin or neurexin. Eur J Neurosci 12: 3953-3962
    • (2000) Eur J Neurosci , vol.12 , pp. 3953-3962
    • Van Renterghem, C.1    Iborra, C.2    Martin-Moutot, N.3
  • 28
    • 0034551770 scopus 로고    scopus 로고
    • A-Latroxin releases calcium in frog motor nerve terminals
    • Tsang CW, Elrick DB, Charlton MP (2000) a-Latroxin releases calcium in frog motor nerve terminals. J Neurosci 20: 8685-8692
    • (2000) J Neurosci , vol.20 , pp. 8685-8692
    • Tsang, C.W.1    Elrick, D.B.2    Charlton, M.P.3
  • 29
    • 0342827889 scopus 로고    scopus 로고
    • Structure of a-latrotoxin oligomers reveals that divalent cation-dependent tetramers form membrane pores
    • Orlova EV, Rahman M, Gowen B. et al. (2000) Structure of a-latrotoxin oligomers reveals that divalent cation-dependent tetramers form membrane pores. Nat Struct Biol 7: 48-53
    • (2000) Nat Struct Biol , vol.7 , pp. 48-53
    • Orlova, E.V.1    Rahman, M.2    Gowen, B.3
  • 30
    • 0032529698 scopus 로고    scopus 로고
    • A-Latrotoxin alters spontaneous and depolarization-evoked quantal release from rat adrenal chromaffin cells: Evidence for multiple modes of action
    • Liu J, Misler S (1998) a-Latrotoxin alters spontaneous and depolarization-evoked quantal release from rat adrenal chromaffin cells: Evidence for multiple modes of action. J Neurosci 18: 6113-6125
    • (1998) J Neurosci , vol.18 , pp. 6113-6125
    • Liu, J.1    Misler, S.2
  • 31
    • 0018143535 scopus 로고
    • Release of neurotransmitters and depletion of synaptic vesicles in cerebral cortex slices by a-latrotoxin from black widow spider venom
    • Tzeng MC, Cohen RS, Siekevitz P (1978) Release of neurotransmitters and depletion of synaptic vesicles in cerebral cortex slices by a-latrotoxin from black widow spider venom. Proc Natl Acad Sci USA 75: 4016-4020
    • (1978) Proc Natl Acad Sci USA , vol.75 , pp. 4016-4020
    • Tzeng, M.C.1    Cohen, R.S.2    Siekevitz, P.3
  • 32
    • 33646485088 scopus 로고    scopus 로고
    • Early and late cytotoxic effects of external application of the Alzheimer's A b result from the initial formation and function of A b ion channels
    • Simakova O, Arispe NJ (2006) Early and late cytotoxic effects of external application of the Alzheimer's A b result from the initial formation and function of A b ion channels. Biochemistry 45: 5907-5915
    • (2006) Biochemistry , vol.45 , pp. 5907-5915
    • Simakova, O.1    Arispe, N.J.2
  • 34
    • 34547203205 scopus 로고    scopus 로고
    • A bion channel: 3D structure and relevance to amyloid channel paradigm
    • Lal R, Lin H, Quist A (2007) A b ion channel: 3D structure and relevance to amyloid channel paradigm. Biochim Biophys Acta 1768: 1966-1975
    • (2007) Biochim Biophys Acta , vol.1768 , pp. 1966-1975
    • Lal, R.1    Lin, H.2    Quist, A.3
  • 35
    • 34548788549 scopus 로고    scopus 로고
    • Models of A b ion channels in the membrane suggest that channel formation in the bilayer is a dynamic process
    • Jang H, Zheng J, Nussinov R (2007) Models of A b ion channels in the membrane suggest that channel formation in the bilayer is a dynamic process. Biophys J 93: 1938-1949
    • (2007) Biophys J , vol.93 , pp. 1938-1949
    • Jang, H.1    Zheng, J.2    Nussinov, R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.