Interleukin-21 promotes the development of ulcerative colitis and regulates the proliferation and secretion of follicular T helper cells in the colitides microenvironment

Molecular Medicine Reports

Volumn 11, Issue 2, 2015, Pages 1049-1056

  Yu, Jing ^a   He, Songbing ^a   Liu, Pengfei ^b   Hu, You ^a   Wang, Lei ^a   Wang, Xu ^a   Han, Ye ^a   Zhu, Xinguo ^a  

^a THE FIRST AFFILIATED HOSPITAL OF SOOCHOW UNIVERSITY   (China)

^b NANTONG UNIVERSITY   (China)

Author keywords

Colon cancer; Follicular T helper cells; Interleukin 21; Ulcerative colitis

Indexed keywords

MUS;

BLR1 PROTEIN, MOUSE; CD40 LIGAND; CHEMOKINE RECEPTOR CXCR5; DEXTRAN SULFATE; ICOS PROTEIN, MOUSE; INDUCIBLE T CELL COSTIMULATOR; INTERLEUKIN 21; INTERLEUKIN DERIVATIVE; NEUTRALIZING ANTIBODY; PDCD1 PROTEIN, MOUSE; PROGRAMMED DEATH 1 RECEPTOR; PROTEIN BCL 6;

ANIMAL; C57BL MOUSE; CELL CULTURE; CELL PROLIFERATION; CHEMICALLY INDUCED; COLON; CYTOLOGY; DISEASE MODEL; DRUG EFFECTS; FEMALE; GENETICS; HELPER CELL; KNOCKOUT MOUSE; METABOLISM; MOUSE; PATHOLOGY; SECRETION (PROCESS); TUMOR MICROENVIRONMENT; ULCERATIVE COLITIS;

ANIMALS; ANTIBODIES, NEUTRALIZING; CD40 LIGAND; CELL PROLIFERATION; CELLS, CULTURED; CELLULAR MICROENVIRONMENT; COLITIS, ULCERATIVE; COLON; DEXTRAN SULFATE; DISEASE MODELS, ANIMAL; FEMALE; INDUCIBLE T-CELL CO-STIMULATOR PROTEIN; INTERLEUKINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PROGRAMMED CELL DEATH 1 RECEPTOR; PROTO-ONCOGENE PROTEINS C-BCL-6; RECEPTORS, CXCR5; T-LYMPHOCYTES, HELPER-INDUCER;

EID: 84916233319     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2014.2824     Document Type: Article

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