Inhibition of GADD34, the stress-inducible regulatory subunit of the endoplasmic reticulum stress response, does not enhance functional recovery after spinal cord injury

PLoS ONE

Volumn 9, Issue 11, 2014, Pages

  Ohri, Sujata Saraswat ^a,b   Mullins, Ashley ^a,b   Hetman, Michal ^a,b   Whittemore, Scott R ^a,b  

^a UNIVERSITY OF LOUISVILLE   (United States)

^b University of Louisville School of Medicine   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROTEIN; ELF2ALPHA PROTEIN; GADD34 PROTEIN; GUANABENZ; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; ALPHA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; DDIT3 PROTEIN, MOUSE; EIF2ALPHA KINASE, MOUSE; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; PERK KINASE; PHOSPHOPROTEIN PHOSPHATASE 1; PPP1R15A PROTEIN, MOUSE; PROTEIN KINASE R; PROTEIN SERINE THREONINE KINASE; TUNICAMYCIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL ASSAY; CELL SURVIVAL; CELLULAR STRESS RESPONSE; CONTROLLED STUDY; DISEASE ACTIVITY; DISEASE ASSOCIATION; DRUG EFFECT; DRUG MECHANISM; ENDOPLASMIC RETICULUM STRESS; FEMALE; HINDLIMB; IN VITRO STUDY; IN VIVO STUDY; LOCOMOTION; MOLECULAR DYNAMICS; MOLECULAR PATHOLOGY; MOUSE; NONHUMAN; OLIGODENDROCYTE PRECURSOR CELL; PROTEIN DETERMINATION; PROTEIN FUNCTION; PROTEIN UNFOLDING; SIGNAL TRANSDUCTION; SPINAL CORD INJURY; SURVIVAL RATE; ANIMAL; ANTAGONISTS AND INHIBITORS; C57BL MOUSE; CELL DEATH; CONVALESCENCE; CYTOLOGY; DRUG EFFECTS; ENDOPLASMIC RETICULUM; GENETICS; KNOCKOUT MOUSE; METABOLISM; OLIGODENDROGLIA; PHOSPHORYLATION; PHYSIOLOGY; PROTEIN FOLDING; SPINAL CORD INJURIES; STEM CELL;

ADRENERGIC ALPHA-2 RECEPTOR AGONISTS; ANIMALS; CELL DEATH; EIF-2 KINASE; ENDOPLASMIC RETICULUM; ENDOPLASMIC RETICULUM STRESS; FEMALE; GUANABENZ; LOCOMOTION; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; OLIGODENDROGLIA; PHOSPHORYLATION; PROTEIN FOLDING; PROTEIN PHOSPHATASE 1; PROTEIN-SERINE-THREONINE KINASES; RECOVERY OF FUNCTION; SPINAL CORD INJURIES; STEM CELLS; TRANSCRIPTION FACTOR CHOP; TUNICAMYCIN;

EID: 84915821489     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0109703     Document Type: Article

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