메뉴 건너뛰기




Volumn 5, Issue 1, 2015, Pages 85-92

Ultra-high performance liquid chromatography coupled with time-of-flight mass spectrometry screening and analysis of potential bioactive compounds from traditional chinese medicine Kai-Xin-San, using a multivariate data processing approach and the MetaboLynx tool

Author keywords

[No Author keywords available]

Indexed keywords

BIOMOLECULES; BODY FLUIDS; COMPUTER SOFTWARE; DATA ACQUISITION; DATA HANDLING; DRUG PRODUCTS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIQUIDS; MASS SPECTROMETRY; METABOLITES; NEURODEGENERATIVE DISEASES; RATS;

EID: 84915803819     PISSN: None     EISSN: 20462069     Source Type: Journal    
DOI: 10.1039/c4ra08992h     Document Type: Article
Times cited : (23)

References (20)
  • 1
    • 84897980491 scopus 로고    scopus 로고
    • Potentiating therapeutic effects by enhancing synergism based on active constituents from traditional medicine
    • A. Zhang H. Sun X. Wang Potentiating therapeutic effects by enhancing synergism based on active constituents from traditional medicine Phytother. Res. 2014 28 4 526 533
    • (2014) Phytother. Res. , vol.28 , Issue.4 , pp. 526-533
    • Zhang, A.1    Sun, H.2    Wang, X.3
  • 3
    • 84890483090 scopus 로고    scopus 로고
    • Rapid identification and comparative analysis of the chemical constituents and metabolites of Phellodendri amurensis cortex and Zhibai dihuang pill by ultra-performance liquid chromatography with quadrupole TOF-MS
    • H. Wang H. Sun A. Zhang Y. Li L. Wang H. Shi X. L. Dizou X. Wang Rapid identification and comparative analysis of the chemical constituents and metabolites of Phellodendri amurensis cortex and Zhibai dihuang pill by ultra-performance liquid chromatography with quadrupole TOF-MS J. Sep. Sci. 2013 36 24 3874 3882
    • (2013) J. Sep. Sci. , vol.36 , Issue.24 , pp. 3874-3882
    • Wang, H.1    Sun, H.2    Zhang, A.3    Li, Y.4    Wang, L.5    Shi, H.6    Dizou, X.L.7    Wang, X.8
  • 4
    • 84875913089 scopus 로고    scopus 로고
    • Recent advances in natural products from plants for treatment of liver diseases
    • A. Zhang H. Sun X. Wang Recent advances in natural products from plants for treatment of liver diseases Eur. J. Med. Chem. 2013 63 570 577
    • (2013) Eur. J. Med. Chem. , vol.63 , pp. 570-577
    • Zhang, A.1    Sun, H.2    Wang, X.3
  • 5
    • 84904470744 scopus 로고    scopus 로고
    • Identification and characterization of the chemical constituents of Simiao Wan by ultra high performance liquid chromatography with mass spectrometry coupled to an automated multiple data processing method
    • A. Zhang D. Zou G. Yan Y. Tan H. Sun X. Wang Identification and characterization of the chemical constituents of Simiao Wan by ultra high performance liquid chromatography with mass spectrometry coupled to an automated multiple data processing method J. Sep. Sci. 2014 37 14 1742 1747
    • (2014) J. Sep. Sci. , vol.37 , Issue.14 , pp. 1742-1747
    • Zhang, A.1    Zou, D.2    Yan, G.3    Tan, Y.4    Sun, H.5    Wang, X.6
  • 6
    • 84911463581 scopus 로고    scopus 로고
    • Ultra-performance liquid chromatography tandem mass spectrometry combined with automated MetaboLynx analysis approach to screen the bioactive components and their metabolites in Wen-Xin-Formula
    • H. Cao A. Zhang F. M. Zhang Q. Q. Wang H. Zhang Y. H. Song Y. Zhou H. Sun G. L. Yan Y. Han X. Wang Ultra-performance liquid chromatography tandem mass spectrometry combined with automated MetaboLynx analysis approach to screen the bioactive components and their metabolites in Wen-Xin-Formula Biomed. Chromatogr. 2014 28 12 1774 1781 10.1002/bmc.3220
    • (2014) Biomed. Chromatogr. , vol.28 , Issue.12 , pp. 1774-1781
    • Cao, H.1    Zhang, A.2    Zhang, F.M.3    Wang, Q.Q.4    Zhang, H.5    Song, Y.H.6    Zhou, Y.7    Sun, H.8    Yan, G.L.9    Han, Y.10    Wang, X.11
  • 7
    • 84898657205 scopus 로고    scopus 로고
    • UPLC/MS coupled with a dynamic multiple data processing method for comprehensive detection of chemical constituents of herbal San-Miao-Wan formula
    • D. Zou A. Zhang G. Yan Y. Tan H. Sun X. Wang UPLC/MS coupled with a dynamic multiple data processing method for comprehensive detection of chemical constituents of herbal San-Miao-Wan formula Anal. Methods 2014 6 9 2848 2854
    • (2014) Anal. Methods , vol.6 , Issue.9 , pp. 2848-2854
    • Zou, D.1    Zhang, A.2    Yan, G.3    Tan, Y.4    Sun, H.5    Wang, X.6
  • 8
    • 84870877897 scopus 로고    scopus 로고
    • Pharmacokinetics study of multiple components absorbed in rat plasma after oral administration of Stemonae radix using ultra-performance liquid-chromatography/mass spectrometry with automated MetaboLynx software analysis
    • H. Sun W. Dong A. Zhang W. Wang X. Wang Pharmacokinetics study of multiple components absorbed in rat plasma after oral administration of Stemonae radix using ultra-performance liquid-chromatography/mass spectrometry with automated MetaboLynx software analysis J. Sep. Sci. 2012 35 24 3477 3485
    • (2012) J. Sep. Sci. , vol.35 , Issue.24 , pp. 3477-3485
    • Sun, H.1    Dong, W.2    Zhang, A.3    Wang, W.4    Wang, X.5
  • 9
    • 84885139213 scopus 로고    scopus 로고
    • An effective method for determining the ingredients of Shuanghuanglian formula in blood samples using high-resolution LC-MS coupled with background subtraction and a multiple data processing approach
    • G. L. Yan A. H. Zhang H. Sun Y. Han H. Shi Y. Zhou X. J. Wang An effective method for determining the ingredients of Shuanghuanglian formula in blood samples using high-resolution LC-MS coupled with background subtraction and a multiple data processing approach J. Sep. Sci. 2013 36 19 3191 3199
    • (2013) J. Sep. Sci. , vol.36 , Issue.19 , pp. 3191-3199
    • Yan, G.L.1    Zhang, A.H.2    Sun, H.3    Han, Y.4    Shi, H.5    Zhou, Y.6    Wang, X.J.7
  • 10
    • 84900325914 scopus 로고    scopus 로고
    • Aloe-emodin from KXS (Rheum rhabarbarum) inhibits lipopolysaccharide-induced inflammatory
    • B. Hu H. Zhang X. Meng F. Wang P. Wang Aloe-emodin from KXS (Rheum rhabarbarum) inhibits lipopolysaccharide-induced inflammatory J. Ethnopharmacol. 2014 153 3 846 853
    • (2014) J. Ethnopharmacol. , vol.153 , Issue.3 , pp. 846-853
    • Hu, B.1    Zhang, H.2    Meng, X.3    Wang, F.4    Wang, P.5
  • 11
    • 83555174417 scopus 로고    scopus 로고
    • Effects of a Chinese traditional formula Kai Xin San (KXS) on chronic fatigue syndrome mice induced by forced wheel running
    • Y. Cao Y. Hu P. Liu H. X. Zhao X. J. Zhou Y. M. Wei Effects of a Chinese traditional formula Kai Xin San (KXS) on chronic fatigue syndrome mice induced by forced wheel running J. Ethnopharmacol. 2012 139 1 19 25
    • (2012) J. Ethnopharmacol. , vol.139 , Issue.1 , pp. 19-25
    • Cao, Y.1    Hu, Y.2    Liu, P.3    Zhao, H.X.4    Zhou, X.J.5    Wei, Y.M.6
  • 12
    • 84900461949 scopus 로고    scopus 로고
    • 1H NMR-based metabonomic analysis of the effect of optimized KXS aglycone on the plasma and urine metabolic fingerprints of focal cerebral ischemia-reperfusion rats
    • 1H NMR-based metabonomic analysis of the effect of optimized KXS aglycone on the plasma and urine metabolic fingerprints of focal cerebral ischemia-reperfusion rats J. Ethnopharmacol. 2014 154 1 65 75
    • (2014) J. Ethnopharmacol. , vol.154 , Issue.1 , pp. 65-75
    • Guan, Q.1    Liang, S.2    Wang, Z.3    Yang, Y.4    Wang, S.5
  • 13
    • 84887171750 scopus 로고    scopus 로고
    • Identification and characterization of the related immune-enhancing proteins in crab Scylla paramamosain stimulated with KXS polysaccharides
    • J. Cao Z. Wang Y. Zhang F. Qu L. Guo M. Zhong S. Li H. Zou J. Chen X. Wang Identification and characterization of the related immune-enhancing proteins in crab Scylla paramamosain stimulated with KXS polysaccharides Mol. Immunol. 2014 57 2 263 273
    • (2014) Mol. Immunol. , vol.57 , Issue.2 , pp. 263-273
    • Cao, J.1    Wang, Z.2    Zhang, Y.3    Qu, F.4    Guo, L.5    Zhong, M.6    Li, S.7    Zou, H.8    Chen, J.9    Wang, X.10
  • 14
    • 84879040176 scopus 로고    scopus 로고
    • Qualitative and quantitative analysis of anthraquinones in KXSs by high performance liquid chromatography with diode array detector and mass spectrometry
    • S. Y. Wei W. X. Yao W. Y. Ji J. Q. Wei S. Q. Peng Qualitative and quantitative analysis of anthraquinones in KXSs by high performance liquid chromatography with diode array detector and mass spectrometry Food Chem. 2013 141 3 1710 1715
    • (2013) Food Chem. , vol.141 , Issue.3 , pp. 1710-1715
    • Wei, S.Y.1    Yao, W.X.2    Ji, W.Y.3    Wei, J.Q.4    Peng, S.Q.5
  • 15
    • 77956268940 scopus 로고    scopus 로고
    • The effect of Acorus gramineus on the bioavailabilities and brain concentrations of ginsenosides Rg1, Re and Rb1 after oral administration of Kai-Xin-San preparations in rats
    • W. Wang Q. P. Liao L. H. Quan C. Y. Liu Q. Chang X. M. Liu Y. H. Liao The effect of Acorus gramineus on the bioavailabilities and brain concentrations of ginsenosides Rg1, Re and Rb1 after oral administration of Kai-Xin-San preparations in rats J. Ethnopharmacol. 2010 131 2 313 320
    • (2010) J. Ethnopharmacol. , vol.131 , Issue.2 , pp. 313-320
    • Wang, W.1    Liao, Q.P.2    Quan, L.H.3    Liu, C.Y.4    Chang, Q.5    Liu, X.M.6    Liao, Y.H.7
  • 16
    • 67650251674 scopus 로고    scopus 로고
    • Preventive action of Kai Xin San aqueous extract on depressive-like symptoms and cognition deficit induced by chronic mild stress
    • H. Dang L. Sun X. Liu B. Peng Q. Wang W. Jia Y. Chen A. Pan P. Xiao Preventive action of Kai Xin San aqueous extract on depressive-like symptoms and cognition deficit induced by chronic mild stress Exp. Biol. Med. 2009 234 7 785 793
    • (2009) Exp. Biol. Med. , vol.234 , Issue.7 , pp. 785-793
    • Dang, H.1    Sun, L.2    Liu, X.3    Peng, B.4    Wang, Q.5    Jia, W.6    Chen, Y.7    Pan, A.8    Xiao, P.9
  • 17
    • 84866165011 scopus 로고    scopus 로고
    • A standardized Chinese herbal decoction, kai-xin-san, restores decreased levels of neurotransmitters and neurotrophic factors in the brain of chronic stress-induced depressive rats
    • K. Y. Zhu Q. Q. Mao S. P. Ip R. C. Choi T. T. Dong D. T. Lau K. W. Tsim A standardized Chinese herbal decoction, kai-xin-san, restores decreased levels of neurotransmitters and neurotrophic factors in the brain of chronic stress-induced depressive rats J. Evidence-Based Complementary Altern. Med. 2012 2012 149256
    • (2012) J. Evidence-Based Complementary Altern. Med. , vol.2012 , pp. 149256
    • Zhu, K.Y.1    Mao, Q.Q.2    Ip, S.P.3    Choi, R.C.4    Dong, T.T.5    Lau, D.T.6    Tsim, K.W.7
  • 18
    • 84885436459 scopus 로고    scopus 로고
    • Metabolic pathways of T-2 toxin in in vivo and in vitro systems of Wistar rats
    • S. Yang Y. Li X. Cao D. Hu Z. Wang Y. Wang J. Shen S. Zhang Metabolic pathways of T-2 toxin in in vivo and in vitro systems of Wistar rats J. Agric. Food Chem. 2013 61 40 9734 9743
    • (2013) J. Agric. Food Chem. , vol.61 , Issue.40 , pp. 9734-9743
    • Yang, S.1    Li, Y.2    Cao, X.3    Hu, D.4    Wang, Z.5    Wang, Y.6    Shen, J.7    Zhang, S.8
  • 19
    • 84862142558 scopus 로고    scopus 로고
    • In vitro metabolism of cyadox in rat, chicken and swine using ultra-performance liquid chromatography quadrupole time-of-flight mass spectrometry
    • H. Wu L. Li J. Shen Y. Wang K. Liu S. Zhang In vitro metabolism of cyadox in rat, chicken and swine using ultra-performance liquid chromatography quadrupole time-of-flight mass spectrometry J. Pharm. Biomed. Anal. 2012 67-68 175 185
    • (2012) J. Pharm. Biomed. Anal. , vol.67-68 , pp. 175-185
    • Wu, H.1    Li, L.2    Shen, J.3    Wang, Y.4    Liu, K.5    Zhang, S.6
  • 20
    • 70149116668 scopus 로고    scopus 로고
    • Use of ultra-high-pressure liquid chromatography-quadrupole time-of-flight MS to discover the presence of pesticide metabolites in food samples
    • F. Hernández S. Grimalt O. J. Pozo J. V. Sancho Use of ultra-high-pressure liquid chromatography-quadrupole time-of-flight MS to discover the presence of pesticide metabolites in food samples J. Sep. Sci. 2009 32 13 2245 2261
    • (2009) J. Sep. Sci. , vol.32 , Issue.13 , pp. 2245-2261
    • Hernández, F.1    Grimalt, S.2    Pozo, O.J.3    Sancho, J.V.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.