Ultra-performance liquid chromatography tandem mass spectrometry combined with automated MetaboLynx analysis approach to screen the bioactive components and their metabolites in Wen-Xin-Formula

Biomedical Chromatography

Volumn 28, Issue 12, 2014, Pages 1774-1781

  Cao, Hongxin ^a   Zhang, Aihua ^b   Zhang, Fang mei ^b   Wang, Qin qin ^b   Zhang, He ^b   Song, Yan hua ^b   Zhou, Ying ^b   Sun, Hui ^b   Yan, Guang li ^b   Han, Ying ^b   Wang, Xijun ^b  

^a INSTITUTE OF CHINESE MATERIA MEDICA   (China)

^b HEILONGJIANG UNIVERSITY OF CHINESE MEDICINE   (China)

Author keywords

Constituents; Identification; Metabolite; MetaboLynx; UPLC ESI Q TOF high definition mass spectrometry (HDMS); Wen Xin Formula

Indexed keywords

ALKALOIDS; BIOMOLECULES; ELECTROSPRAY IONIZATION; INDUCTIVELY COUPLED PLASMA; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; UNSATURATED FATTY ACIDS;

BERBERIS; BIOACTIVE COMPONENTS; CONSTITUENT; HIGH DEFINITION; IDENTIFICATION; METABOLYNX; ORAL ADMINISTRATION; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY; UPLC-ESI-Q-TOF- HIGH DEFINITION MASS SPECTROMETRY; WEN-XIN-FORMULA;

METABOLITES;

3 METHYL ELLAGIC ACID; 3,3' DI O METHYLELLAGIC ACID; 9,12,13 TRIHYDROXY 10,15 OCTADECADIENOIC ACID; ALBIFLORIN; BERBERINE; BEROLINE; COPTISINE; DRUG METABOLITE; EPIBERBERINE; GALLOYLPAEONIFLORIN; GINSENOSIDE RB 1; GINSENOSIDE RG 1; HERBACEOUS AGENT; JATRORRHIZINE; LINALOOL 3,6 OXIDE 6 O BETA DEXTRO XYLOPYRANOSYL BETA DEXTRO GLUCOPYRANOSIDE; MAGNOFLORINE; OXYPAEONIFLORIN; PAEONIFLORIN; PALMATINE; PROTOCATECHUIC ACID 3 GLUCOSIDE; SYRINGIC ACID 4 BETA DEXTRO GLUCOPYRANOSIDE; UNCLASSIFIED DRUG; WEN XIN FORMULA; ORGANIC COMPOUND;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DATA PROCESSING; DRUG IDENTIFICATION; ELECTROSPRAY MASS SPECTROMETRY; MALE; METABOLYNX METHOD; NONHUMAN; QUADRUPOLE MASS SPECTROMETRY; RAT; TANDEM MASS SPECTROMETRY; TEMPERATURE; TIME OF FLIGHT MASS SPECTROMETRY; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY; ANIMAL; BLOOD; CHEMISTRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; METABOLISM; METABOLOME; PROCEDURES; WISTAR RAT;

ANIMALS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUGS, CHINESE HERBAL; MALE; METABOLOME; ORGANIC CHEMICALS; RATS; RATS, WISTAR; TANDEM MASS SPECTROMETRY;

EID: 84911463581     PISSN: 02693879     EISSN: 10990801     Source Type: Journal    
DOI: 10.1002/bmc.3220     Document Type: Article

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