Effects of a Chinese traditional formula Kai Xin San (KXS) on chronic fatigue syndrome mice induced by forced wheel running

Journal of Ethnopharmacology

Volumn 139, Issue 1, 2012, Pages 19-25

  Cao, Yin ^a,b   Hu, Yuan ^a   Liu, Ping ^a   Zhao, Hai Xia ^a,c   Zhou, Xiao Jiang ^a   Wei, Ying Mei ^b  

^a CHINESE PLA GENERAL HOSPITAL   (China)

^b BENGBU MEDICAL COLLEGE   (China)

^c TIANJIN UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

Author keywords

Chronic fatigue syndrome; Kai Xin San; Wheel running

Indexed keywords

CHINESE DRUG; GLYCOGEN; INTERLEUKIN 2; INTERLEUKIN 4; KAI XIN SAN; LACTATE DEHYDROGENASE; LACTIC ACID; MODAFINIL; UNCLASSIFIED DRUG;

ACORUS GRAMINEUS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL PROLIFERATION; CHINESE HERB; CHRONIC FATIGUE SYNDROME; CONTROLLED STUDY; DOSE RESPONSE; DRUG SCREENING; EXPERIMENTAL MOUSE; GINSENG; GLYCOGEN LIVER LEVEL; MALE; MEDICINAL MUSHROOM; MOUSE; MUSCLE LEVEL; NONHUMAN; POLYGALA TENUIFOLIA; SPLEEN CELL; UREA NITROGEN BLOOD LEVEL; WOLFIPORIA COCOS;

ANGIOSPERMS; ANIMALS; BLOOD UREA NITROGEN; CELL PROLIFERATION; DISEASE MODELS, ANIMAL; DRUGS, CHINESE HERBAL; FATIGUE SYNDROME, CHRONIC; GLYCOGEN; INTERLEUKIN-2; INTERLEUKIN-4; L-LACTATE DEHYDROGENASE; LACTIC ACID; MALE; MICE; PHYSICAL EXERTION; SPLEEN; TESTOSTERONE;

ACORUS GRAMINEUS; MUS; PANAX GINSENG; POLYGALA; POLYGALA TENUIFOLIA; PORIA COCOS; WOLFIPORIA COCOS;

EID: 83555174417     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2011.08.030     Document Type: Article

References (27)

1. N. Afari, and D. Buchwald Chronic fatigue syndrome: a review American Journal of Psychiatry 160 2003 221 236 (Pubitemid 41110447)
2. S. Arver, A.S. Dobs, A.W. Meikle, R.P. Allen, S.W. Sanders, and N.A. Mazer Improvement of sexual function in testosterone deficient men treated for 1 year with a permeation enhanced testosterone transdermal system The Journal of Urology 155: 1996 1604 1608 (Pubitemid 26126959)
3. E.A. Bae, Y.J. Hyun, M.K. Choo, J.K. Oh, J.H. Ryu, and D.H. Kim Protective effect of fermented red ginseng on a transient focal ischemic rats Archives of Pharmacal Research 27 2004 1136 1140
4. M.S. Bahrke, and W.R. Morgan Evaluation of the ergogenic properties of ginseng: an update Sports Medicine 29 2000 113 133 (Pubitemid 30110383)
5. X.Y. Chen, L.N. Zhang, P. Chi, and K. Chenung Immunopotentiation and anti-tumor activity of carboxymethylated-sulfated β-(1 → 3)-d-glucan from Poria cocos β-(1 → 3)-d-glucan from Poria cocos International Immunopharmacology 10 2010 398 405
6. J. Cho, Y.H. Kim, J.-Y. Kong, C.H. Yang, and C.G. Park Protection of cultured rat cortical neurons from excitotoxicity by asarone, a major essential oil component in the rhizomes of Acorus gramineus Life Sciences 71 2002 591 599 (Pubitemid 34607650)
7. A. Ferreira, S. Lamarque, P. Boyer, F. Perez-Diaz, R. Jouvent, and C. Cohen-Salmon Spontaneous appetence for wheel-running a model of dependency on physical activity in rat European Psychiatry 21 2006 580 588 (Pubitemid 44873073)
8. B.N. Greenwood, T.E. Foley, H.E. Day, S. Campeau, S.F. Maier, and M. Fleshner Freewheel running prevents learned helplessness behavioral depression: role of dorsal raphe serotonergic neurons The Journal of Neuroscience 23 2003 2889 2898 (Pubitemid 36418625)
9. B.N. Greenwood, T.E. Foley, D. Burhans, S.F. Maier, and M. Fleshener The consequences of uncontrollable stress are sensitive to duration of prior wheel running Brain Research 1033 2005 164 178 (Pubitemid 40193411)
10. Y. Hu, P. Liu, K. Rahman, D.X. Wang, M.L. Chen, T.T. Xie, and D.H. Gou Behavioral and biochemical effects of Kaixin-San, a traditional Chinese medicinal empirical formula Drug Development Research 69 2008 267 271
11. Y. Hu, H.B. Liao, D.H. Guo, P. Liu, Y.Y. Wang, and K. Rahman Antidepressant-like effects of 3,6′-disinapoyl sucrose on hippocampal neuronal plasticity and neurotrophic signal pathway in chronically mild stressed rats Neurochemistry International 56 2009 461 465
12. E.B. Larson, and M.E. Carroll Wheel running as a predictor of cocaine self-administration and reinstatement in female rats Pharmacology Biochemistry Behavior 82 2005 590 600 (Pubitemid 41827603)
13. B.M. Lee, S.K. Lee, and H.S. Kim Inhibition of oxidative DNA damage, 8-OHdG, and carbonylcontents in smokers treated with antioxidants (vitamin E, vitamin C, beta-carotene and red ginseng) Cancer 132 1998 219 227 (Pubitemid 28535208)
14. B.T. Lett, V.L. Grant, M.J. Byrne, and M.T. Koh Pairings of a distinctive chamber with the aftereffect of wheel running produce conditioned place preference Appetite 34 2000 87 94 (Pubitemid 30160695)
15. X.Y. Lian, Z. Zhang, and J.L. Stringer Protective effects of ginseng components in a rodentmodel of neurodegeneration Annals of Neurology 57 2005 642 648 (Pubitemid 40628852)
16. P. Liu, Y. Hu, D.-H. Guo, D.-X. Wang, H.-H. Tu, L. Mab, T.-T. Xie, and L.-Y. Kong Potential antidepressant properties of Radix Polygalae (Yuan Zhi) Phytomedicine 17 2010 794 799
17. W.F. Mathes, and R.B. Kanarek Wheel running attenuates the antinociceptive properties of morphine and its metabolite, morphine-6- glucuronide in rats Physiology and Behavior 74 2001 245 251 (Pubitemid 32879383)
18. J.K Park, U. Namgung, C.J. Lee, J.O. Park, S.H. Jin, O.B. Kwon, S.R. Ko, S.W. Kim, E.J. Kang, J.H. Ko, S.M. Lee, D.H. Kim, and M.H. Won Calcium-independent CaMKII activity is involved in ginsenoside Rb1-mediated neuronal recovery after hypoxic damage Life Sciences 76 2005 1013 1025 (Pubitemid 39643401)
19. D. Racciatti, J. Vecchiet, A. Ceccomancini, F. Ricci, and E. Pizzigallo Chronic fatigue syndrome following a toxic exposure The Science of Total Environment 270 2001 27 31 (Pubitemid 32273552)
20. J.S. Rhodes, and T. Garland Differential sensitivity to acute administration of Ritalin, apomorphine, SHC 23390, but not racolpride in mice selectively bred for hyperactive wheel-running behavior Psychopharmacology 167 2003 175 242
21. S. Shor Hypothesis paper: pathogenesis of chronic fatigue syndrome: a multisystem hypothesis Journal of Chronic Fatigue Syndrome 11 2003 51 68 (Pubitemid 37315128)
22. K. Toshihiko Possible involvement of brain cytokines and 5-HT system in chronic fatigue syndrome International Congress Series 1287 2006 251 255
23. C. Wang, G. Alexander, N. Berman, B. Salehian, T. Davidson, V. McDonald, B. Steiner, L. Hull, C. Callegari, and R.S. Swerdloff Testosterone replacement therapy improves mood in hypogonadal men: a clinical research canter study Journal of Clinical Endocrinology and Metabolism 81 1996 3578 3583 (Pubitemid 26339918)
24. J.L. Wang, P. Liu, D.X. Wang, H.H. Tu, and G.Y. Chen The effect of Kai Xin San on behavior of chronic stress in rats and P-CREB expression in hippocampus China Journal of Chinese Media 32 2007 1555 1557
25. J. Wang, S.S. Li, Y.Y. Fan, Y. Chen, D. Liu, H.R. Cheng, X.G. Gao, and Y.F. Zhou Ginseng polysaccharides possess an anti-fatigue activity Journal of Ethnopharmacology 130 2010 421 423
26. E. Willoughby Modafinil for fatigue in multiple sclerosis Journal of Neurology, Neurosurgery and Psychiatry 72 2002 150
27. T. Yoshikawa, Y. Akiyoshi, T. Susumu, H. Tokado, K. Fukuzaki, R. Nagata, K. Samukawa, H. Iwao, and G. Kito Ginsenoside Rb1 reduces neurodegeneration in the peri-infarct area of a thromboembolic stroke model in non-human primates Pharmacological Sciences 107 2008 32 40 (Pubitemid 351744082)