Lidamycin inhibits tumor initiating cells of hepatocellular carcinoma Huh7 through GSK3β/β-catenin pathway

Molecular Carcinogenesis

Volumn 54, Issue 1, 2015, Pages 1-8

  Chen, Yi ^a,b   Yu, Dongke ^b   Zhang, Caixia ^b   Shang, Boyang ^b   He, Hongwei ^b   Chen, Jinjing ^b   Zhang, Hao ^b   Zhao, Wuli ^b   Wang, Zhen ^b   Xu, Xiaoyu ^a   Zhen, Yongsu ^b   Shao, Rong guang ^b  

^a SOUTHWEST UNIVERSITY   (China)

^b INSTITUTE OF MEDICINAL BIOTECHNOLOGY   (China)

Author keywords

EpCAM; GSK3 catenin pathway; Hepatocellular carcinoma; Lidamycin; Tumor initiating cells

Indexed keywords

ALDEHYDE DEHYDROGENASE; ANTINEOPLASTIC ANTIBIOTIC; BETA CATENIN; ENEDIYNE; EPITHELIAL CELL ADHESION MOLECULE; GLYCOGEN SYNTHASE KINASE 3BETA; LIDAMYCIN; UNCLASSIFIED DRUG; AMINOGLYCOSIDE; ANTIBIOTIC C 1027; GLYCOGEN SYNTHASE KINASE 3; GLYCOGEN SYNTHASE KINASE 3 BETA;

ALDEFLUOR ASSAY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; ASSAY; CELL POPULATION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LIMIT OF QUANTITATION; LIVER CELL CARCINOMA; MOUSE; NONHUMAN; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; SPHERE FORMATION ASSAY; SURFACE MARKER ASSAY; TUMOR VOLUME; WESTERN BLOTTING; ANIMAL; CANCER STEM CELL; CARCINOMA, HEPATOCELLULAR; DRUG EFFECTS; DRUG SCREENING; EXPERIMENTAL LIVER NEOPLASM; LIVER NEOPLASMS; METABOLISM; NUDE MOUSE; PATHOLOGY; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

AMINOGLYCOSIDES; ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; BETA CATENIN; CARCINOMA, HEPATOCELLULAR; CELL LINE, TUMOR; ENEDIYNES; GLYCOGEN SYNTHASE KINASE 3; HUMANS; LIVER NEOPLASMS; LIVER NEOPLASMS, EXPERIMENTAL; MICE; MICE, NUDE; NEOPLASTIC STEM CELLS; SIGNAL TRANSDUCTION; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84914687394     PISSN: 08991987     EISSN: 10982744     Source Type: Journal    
DOI: 10.1002/mc.22069     Document Type: Article

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