Inhibition of mouse embryonic carcinoma cell growth by Lidamycin through down-regulation of embryonic stem cell-like genes Oct4, Sox2 and Myc

Investigational New Drugs

Volumn 29, Issue 6, 2011, Pages 1188-1197

  Zhen, Hong Ying ^a   He, Qi Hua ^a   Zhen, Yong Zhan ^a,b   Wang, Shu Ling ^a   Liu, Yi Nan ^a   Wu, Wei Hua ^a   Zhang, Xiao Yan ^a   Lu, Ai Li ^a   Shen, Li ^a  

^a PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

^b NORTH CHINA COAL MEDICAL COLLEGE   (China)

Author keywords

Anti cancer; Embryonic stem cell (ESC) like genes Oct4; Lidamycin; Mouse embryonic carcinoma (EC) cell

Indexed keywords

ANTIBIOTIC C 1027; DOXORUBICIN; AMINOGLYCOSIDE; ANTINEOPLASTIC ANTIBIOTIC; ENEDIYNE; MYC PROTEIN; OCTAMER TRANSCRIPTION FACTOR 4; SOX2 PROTEIN, MOUSE; TRANSCRIPTION FACTOR SOX;

ANIMAL CELL; APOPTOSIS; ARTICLE; CANCER CHEMOTHERAPY; CANCER INHIBITION; CELL DEATH; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL RENEWAL; COLONY FORMING CELL; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOWN REGULATION; DRUG MECHANISM; EMBRYO; EMBRYONAL CARCINOMA STEM CELL; FLOW CYTOMETRY; G1 PHASE CELL CYCLE CHECKPOINT; IMMUNOCYTOCHEMISTRY; MOUSE; NONHUMAN; OCT4 GENE; ONCOGENE MYC; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SOX2 GENE; TUMOR GENE; WESTERN BLOTTING; ANIMAL; DOSE RESPONSE; DRUG EFFECT; DRUG POTENTIATION; GENETICS; HUMAN; METABOLISM; TIME; TUMOR CELL LINE;

AMINOGLYCOSIDES; ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; CELL LINE, TUMOR; CELL PROLIFERATION; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; DOXORUBICIN; DRUG SYNERGISM; EMBRYONAL CARCINOMA STEM CELLS; ENEDIYNES; FLOW CYTOMETRY; HUMANS; MICE; OCTAMER TRANSCRIPTION FACTOR-3; PROTO-ONCOGENE PROTEINS C-MYC; SOXB1 TRANSCRIPTION FACTORS; TIME FACTORS;

EID: 84856027947     PISSN: 01676997     EISSN: 15730646     Source Type: Journal    
DOI: 10.1007/s10637-010-9463-x     Document Type: Article

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