Restored expression of the tumor suppressor gene RUNX3 reduces cancer stem cells in hepatocellular carcinoma by suppressing Jagged1-Notch signaling

Oncology Reports

Volumn 26, Issue 3, 2011, Pages 523-531

  Nishina, Shin Ichi ^a   Shiraha, Hidenori ^a   Nakanishi, Yutaka ^a   Tanaka, Shigetomi ^a   Matsubara, Minoru ^a   Takaoka, Nobuyuki ^a   Uemura, Masayuki ^a   Horiguchi, Shigeru ^a   Kataoka, Junro ^a   Iwamuro, Masaya ^a   Yagi, Takahito ^a   Yamamoto, Kazuhide ^a  

^a OKAYAMA UNIVERSITY   (Japan)

Author keywords

Cancer stem cell; Hepatocellular carcinoma; Jagged 1; Notch signaling; Runt related transcription factor 3

Indexed keywords

COMPLEMENTARY DNA; JAGGED1; NOTCH RECEPTOR; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR RUNX3;

ADULT; AGED; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CANCER PATIENT; CANCER STEM CELL; CARCINOGENICITY; CLINICAL ARTICLE; CONTROLLED STUDY; DOWN REGULATION; ENZYME REGULATION; FEMALE; GENE EXPRESSION REGULATION; GENE REPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; LIVER CELL CARCINOMA; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RUNX3 GENE; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; TUMOR SUPPRESSOR GENE; UPREGULATION;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ANIMALS; CALCIUM-BINDING PROTEINS; CARCINOMA, HEPATOCELLULAR; CELL LINE, TUMOR; CORE BINDING FACTOR ALPHA 3 SUBUNIT; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, REPORTER; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; LIVER NEOPLASMS; LUCIFERASES, FIREFLY; MALE; MEMBRANE PROTEINS; MICE; MICE, SCID; MIDDLE AGED; NEOPLASM TRANSPLANTATION; NEOPLASTIC STEM CELLS; RECEPTORS, NOTCH; RECOMBINANT PROTEINS; REGULATORY ELEMENTS, TRANSCRIPTIONAL; SIGNAL TRANSDUCTION; TRANSCRIPTION, GENETIC; TRANSPLANTATION, HETEROLOGOUS; TUMOR BURDEN; YOUNG ADULT;

EID: 79960022317     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.2011.1336     Document Type: Article

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