메뉴 건너뛰기




Volumn 4, Issue 3, 2008, Pages 179-192

In search of liver cancer stem cells

Author keywords

ALDH; CD133; HCC; Liver cancer stem cells; Liver regeneration

Indexed keywords

ALDEHYDE DEHYDROGENASE; CD133 ANTIGEN; GLYCOPROTEIN; LEUKOCYTE ANTIGEN; PEPTIDE;

EID: 58149200071     PISSN: 15508943     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12015-008-9035-z     Document Type: Review
Times cited : (24)

References (111)
  • 2
    • 33747830764 scopus 로고    scopus 로고
    • Hepatocellular carcinoma pathogenesis: From genes to environment
    • P. A. Farazi R. A. DePinho 2006 Hepatocellular carcinoma pathogenesis: from genes to environment Nature Review Cancer 6 674 687
    • (2006) Nature Review Cancer , vol.6 , pp. 674-687
    • Farazi, P.A.1    Depinho, R.A.2
  • 4
    • 0036699940 scopus 로고    scopus 로고
    • Molecular pathogenesis of human hepatocellular carcinoma
    • S. S. Thorgeirsson J. W. Grisham 2002 Molecular pathogenesis of human hepatocellular carcinoma Nature Genetics 31 339 346
    • (2002) Nature Genetics , vol.31 , pp. 339-346
    • Thorgeirsson, S.S.1    Grisham, J.W.2
  • 5
    • 5044234897 scopus 로고    scopus 로고
    • Hepatocellular carcinoma: Role of hepatitis B and hepatitis C viruses' proteins in hepatocarcinogenesis
    • M. Anzola 2004 Hepatocellular carcinoma: role of hepatitis B and hepatitis C viruses' proteins in hepatocarcinogenesis Journal of Viral Hepatitis 11 383 393
    • (2004) Journal of Viral Hepatitis , vol.11 , pp. 383-393
    • Anzola, M.1
  • 8
    • 0842321807 scopus 로고    scopus 로고
    • Diabetes increases the risk of chronic liver disease and hepatocellular carcinoma
    • H. B. El-Serag T. Tran J. E. Everhart 2004 Diabetes increases the risk of chronic liver disease and hepatocellular carcinoma Gastroenterology 126 460 468
    • (2004) Gastroenterology , vol.126 , pp. 460-468
    • El-Serag, H.B.1    Tran, T.2    Everhart, J.E.3
  • 9
    • 0028001640 scopus 로고
    • Concurrent hepatitis B and C virus infection and risk of hepatocellular carcinoma in cirrhosis. a prospective study
    • L. Benvegnu G. Fattovich F. Noventa 1994 Concurrent hepatitis B and C virus infection and risk of hepatocellular carcinoma in cirrhosis. A prospective study Cancer 74 2442 2448
    • (1994) Cancer , vol.74 , pp. 2442-2448
    • Benvegnu, L.1    Fattovich, G.2    Noventa, F.3
  • 10
    • 7044260782 scopus 로고    scopus 로고
    • Pathogenesis of hepatitis B virus-related hepatocellular carcinoma: Old and new paradigms
    • C. Brechot 2004 Pathogenesis of hepatitis B virus-related hepatocellular carcinoma: old and new paradigms Gastroenterology 127 56 61
    • (2004) Gastroenterology , vol.127 , pp. 56-61
    • Brechot, C.1
  • 11
    • 7044272630 scopus 로고    scopus 로고
    • Hepatocellular carcinoma in cirrhosis: Incidence and risk factors
    • G. Fattovich T. Stroffolini I. Zagni 2004 Hepatocellular carcinoma in cirrhosis: incidence and risk factors Gastroenterology 127 35 50
    • (2004) Gastroenterology , vol.127 , pp. 35-50
    • Fattovich, G.1    Stroffolini, T.2    Zagni, I.3
  • 12
    • 7044260779 scopus 로고    scopus 로고
    • Environmental factors and risk for hepatocellular carcinoma
    • M. C. Yu J. M. Yuan 2004 Environmental factors and risk for hepatocellular carcinoma Gastroenterology 127 72 78
    • (2004) Gastroenterology , vol.127 , pp. 72-78
    • Yu, M.C.1    Yuan, J.M.2
  • 13
    • 0033545541 scopus 로고    scopus 로고
    • Rising incidence of hepatocellular carcinoma in the United States
    • H. B. El-Serag A. C. Mason 1999 Rising incidence of hepatocellular carcinoma in the United States New England Journal of Medicine 340 745 750
    • (1999) New England Journal of Medicine , vol.340 , pp. 745-750
    • El-Serag, H.B.1    Mason, A.C.2
  • 14
    • 20344392430 scopus 로고    scopus 로고
    • Hepatocellular carcinoma: Epidemiology, risk factors, and screening
    • M. Sherman 2005 Hepatocellular carcinoma: epidemiology, risk factors, and screening Seminars in Liver Disease 25 143 154
    • (2005) Seminars in Liver Disease , vol.25 , pp. 143-154
    • Sherman, M.1
  • 15
    • 7044239399 scopus 로고    scopus 로고
    • Hepatocellular carcinoma: Current management and future trends
    • B. I. Carr 2004 Hepatocellular carcinoma: current management and future trends Gastroenterology 127 218 224
    • (2004) Gastroenterology , vol.127 , pp. 218-224
    • Carr, B.I.1
  • 16
    • 33847702042 scopus 로고    scopus 로고
    • Liver resection and transplantation in the management of hepatocellular carcinoma: A review
    • W. T. Kassahun J. Fangmann J. Harms 2006 Liver resection and transplantation in the management of hepatocellular carcinoma: a review Experimental and Clinical Transplantation 4 549 558
    • (2006) Experimental and Clinical Transplantation , vol.4 , pp. 549-558
    • Kassahun, W.T.1    Fangmann, J.2    Harms, J.3
  • 17
    • 7044233345 scopus 로고    scopus 로고
    • Living donor liver transplantation for hepatocellular carcinoma
    • L. Kulik M. Abecassis 2004 Living donor liver transplantation for hepatocellular carcinoma Gastroenterology 127 277 282
    • (2004) Gastroenterology , vol.127 , pp. 277-282
    • Kulik, L.1    Abecassis, M.2
  • 18
    • 0032742183 scopus 로고    scopus 로고
    • Intention-to-treat analysis of surgical treatment for early hepatocellular carcinoma: Resection versus transplantation
    • J. M. Llovet J. Fuster J. Bruix 1999 Intention-to-treat analysis of surgical treatment for early hepatocellular carcinoma: resection versus transplantation Hepatology 30 1434 1440
    • (1999) Hepatology , vol.30 , pp. 1434-1440
    • Llovet, J.M.1    Fuster, J.2    Bruix, J.3
  • 19
    • 7044253326 scopus 로고    scopus 로고
    • Liver transplantation for hepatocellular carcinoma
    • M. Schwartz 2004 Liver transplantation for hepatocellular carcinoma Gastroenterology 127 268 276
    • (2004) Gastroenterology , vol.127 , pp. 268-276
    • Schwartz, M.1
  • 20
    • 0345299824 scopus 로고    scopus 로고
    • Liver transplantation for the treatment of small hepatocellular carcinomas in patients with cirrhosis
    • V. Mazzaferro E. Regalia R. Doci 1996 Liver transplantation for the treatment of small hepatocellular carcinomas in patients with cirrhosis New England Journal of Medicine 334 693 699
    • (1996) New England Journal of Medicine , vol.334 , pp. 693-699
    • Mazzaferro, V.1    Regalia, E.2    Doci, R.3
  • 21
    • 0034793993 scopus 로고    scopus 로고
    • Nonsurgical treatment of hepatocellular carcinoma
    • A. Aguayo Y. Z. Patt 2001 Nonsurgical treatment of hepatocellular carcinoma Seminars in Oncology 28 503 513
    • (2001) Seminars in Oncology , vol.28 , pp. 503-513
    • Aguayo, A.1    Patt, Y.Z.2
  • 22
    • 0036775308 scopus 로고    scopus 로고
    • Radiofrequency ablation of liver tumors: Influence of technique and tumor size
    • B. W. Kuvshinoff D. M. Ota 2002 Radiofrequency ablation of liver tumors: influence of technique and tumor size Surgery 132 605 611
    • (2002) Surgery , vol.132 , pp. 605-611
    • Kuvshinoff, B.W.1    Ota, D.M.2
  • 24
    • 0037308133 scopus 로고    scopus 로고
    • Systematic review of randomized trials for unresectable hepatocellular carcinoma: Chemoembolization improves survival
    • J. M. Llovet J. Bruix 2003 Systematic review of randomized trials for unresectable hepatocellular carcinoma: chemoembolization improves survival Hepatology 37 429 442
    • (2003) Hepatology , vol.37 , pp. 429-442
    • Llovet, J.M.1    Bruix, J.2
  • 25
    • 33646428091 scopus 로고    scopus 로고
    • Normal stem cells and cancer stem cells: The niche matters
    • L. Li W. B. Neaves 2006 Normal stem cells and cancer stem cells: the niche matters Cancer Research 66 4553 4557
    • (2006) Cancer Research , vol.66 , pp. 4553-4557
    • Li, L.1    Neaves, W.B.2
  • 26
  • 27
    • 33644826473 scopus 로고    scopus 로고
    • Roots and stems: Stem cells in cancer
    • K. Polyak C. W. Hahn 2005 Roots and stems: stem cells in cancer Nature Medicine 11 296 300
    • (2005) Nature Medicine , vol.11 , pp. 296-300
    • Polyak, K.1    Hahn, C.W.2
  • 28
    • 0035499267 scopus 로고    scopus 로고
    • Stem cells, cancer and cancer stem cells
    • T. Reya S. J. Morrison M. F. Clarke 2001 Stem cells, cancer and cancer stem cells Nature 414 105 111
    • (2001) Nature , vol.414 , pp. 105-111
    • Reya, T.1    Morrison, S.J.2    Clarke, M.F.3
  • 29
    • 9244221172 scopus 로고    scopus 로고
    • Tissue repair and stem cell renewal in carcinogenesis
    • P. A. Beachy S. S. Karhadkar D. M. Berman 2004 Tissue repair and stem cell renewal in carcinogenesis Nature 432 324 331
    • (2004) Nature , vol.432 , pp. 324-331
    • Beachy, P.A.1    Karhadkar, S.S.2    Berman, D.M.3
  • 30
    • 33747166468 scopus 로고    scopus 로고
    • Repair and regeneration: Opportunities for carcinogenesis from tissue stem cells
    • S. C. Perryman K. G. Sylvester 2006 Repair and regeneration: opportunities for carcinogenesis from tissue stem cells Journal of Cellular and Molecular Medicine 10 292 308
    • (2006) Journal of Cellular and Molecular Medicine , vol.10 , pp. 292-308
    • Perryman, S.C.1    Sylvester, K.G.2
  • 31
    • 2542601615 scopus 로고    scopus 로고
    • Liver regeneration and repair: Hepatocytes, progenitor cells and stem cells
    • N. Fausto 2004 Liver regeneration and repair: hepatocytes, progenitor cells and stem cells Hepatology 39 1477 1487
    • (2004) Hepatology , vol.39 , pp. 1477-1487
    • Fausto, N.1
  • 33
    • 28544438991 scopus 로고    scopus 로고
    • Liver cancer: The role of stem cells
    • M. R. Alison M. J. Lovell 2005 Liver cancer: the role of stem cells Cell Proliferation 38 407 421
    • (2005) Cell Proliferation , vol.38 , pp. 407-421
    • Alison, M.R.1    Lovell, M.J.2
  • 35
    • 0029819783 scopus 로고    scopus 로고
    • Hepatic stem cells in liver regeneration
    • S. Thorgeirsson 1996 Hepatic stem cells in liver regeneration The FASEB Journal 10 1249 1256
    • (1996) The FASEB Journal , vol.10 , pp. 1249-1256
    • Thorgeirsson, S.1
  • 36
    • 34247504081 scopus 로고    scopus 로고
    • Bone marrow stem cells and liver disease
    • Y. N. Kallis M. R. Alison S. J. Forbes 2007 Bone marrow stem cells and liver disease Gut 56 716 724
    • (2007) Gut , vol.56 , pp. 716-724
    • Kallis, Y.N.1    Alison, M.R.2    Forbes, S.J.3
  • 37
    • 0033553591 scopus 로고    scopus 로고
    • Bone marrow as a potential source of hepatic oval cells
    • B. E. Petersen W. C. Bowen K. D. Patrene 1999 Bone marrow as a potential source of hepatic oval cells Science 284 1168 1170
    • (1999) Science , vol.284 , pp. 1168-1170
    • Petersen, B.E.1    Bowen, W.C.2    Patrene, K.D.3
  • 38
    • 0344155277 scopus 로고    scopus 로고
    • Genetic hits and mutation rate in colorectal tumorigenesis: Versatility of Knudson's theory and implications for cancer prevention
    • A. Bellacosa 2003 Genetic hits and mutation rate in colorectal tumorigenesis: versatility of Knudson's theory and implications for cancer prevention Genes Chromosomes Cancer 38 382 388
    • (2003) Genes Chromosomes Cancer , vol.38 , pp. 382-388
    • Bellacosa, A.1
  • 41
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • D. Hanahan R. A. Weinberg 2000 The hallmarks of cancer Cell 100 57 70
    • (2000) Cell , vol.100 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 42
    • 5444256238 scopus 로고    scopus 로고
    • Self-renewal and solid tumor stem cells
    • M. Al-Hajj M. F. Clarke 2004 Self-renewal and solid tumor stem cells Oncogene 23 7274 7282
    • (2004) Oncogene , vol.23 , pp. 7274-7282
    • Al-Hajj, M.1    Clarke, M.F.2
  • 48
    • 84965820581 scopus 로고
    • The transmission of leukemia of mice with a single cell
    • J. Furth M. C. Kahn 1937 The transmission of leukemia of mice with a single cell American Journal of Cancer 31 276 282
    • (1937) American Journal of Cancer , vol.31 , pp. 276-282
    • Furth, J.1    Kahn, M.C.2
  • 49
    • 84956427297 scopus 로고
    • A direct measurement of the radiation sensitivity of normal mouse bone marrow cells
    • J. E. Till E. A. McCulloch 1961 A direct measurement of the radiation sensitivity of normal mouse bone marrow cells Radiation Research 14 213 222
    • (1961) Radiation Research , vol.14 , pp. 213-222
    • Till, J.E.1    McCulloch, E.A.2
  • 50
    • 0028091194 scopus 로고
    • A cell initiating human acute myeloid leukemia after transplantation into SCID mice
    • T. Lapidot C. Sirard J. Vormoor 1994 A cell initiating human acute myeloid leukemia after transplantation into SCID mice Nature 367 645 648
    • (1994) Nature , vol.367 , pp. 645-648
    • Lapidot, T.1    Sirard, C.2    Vormoor, J.3
  • 51
    • 0030789242 scopus 로고    scopus 로고
    • Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell
    • D. Bonnet J. E. Dick 1997 Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell Nature Medicine 3 730 737
    • (1997) Nature Medicine , vol.3 , pp. 730-737
    • Bonnet, D.1    Dick, J.E.2
  • 53
    • 33749515476 scopus 로고    scopus 로고
    • Targeting of CD44 eradicates human acute myeloid leukemic stem cells
    • L. Jin K. J. Hope Q. Zhai 2006 Targeting of CD44 eradicates human acute myeloid leukemic stem cells Nature Medicine 12 1167 1174
    • (2006) Nature Medicine , vol.12 , pp. 1167-1174
    • Jin, L.1    Hope, K.J.2    Zhai, Q.3
  • 54
    • 34250732230 scopus 로고    scopus 로고
    • Aldehyde dehydrogenase activity in leukemic blasts defines a subgroup of acute myeloid leukemia with adverse prognosis and superior NOD/SCID engrafting potential
    • A. M. S. Cheung T. S. K. Wan J. C. K. Leung 2007 Aldehyde dehydrogenase activity in leukemic blasts defines a subgroup of acute myeloid leukemia with adverse prognosis and superior NOD/SCID engrafting potential Leukemia 21 1423 1430
    • (2007) Leukemia , vol.21 , pp. 1423-1430
    • Cheung, A.M.S.1    Wan, T.S.K.2    Leung, J.C.K.3
  • 55
    • 7244223336 scopus 로고    scopus 로고
    • Characteristics of acute lymphoblastic leukemia progenitor cells
    • C. V. Cox R. S. Evely A. Oakhill 2004 Characteristics of acute lymphoblastic leukemia progenitor cells Blood 104 2919 2915
    • (2004) Blood , vol.104 , pp. 2919-2915
    • Cox, C.V.1    Evely, R.S.2    Oakhill, A.3
  • 56
    • 33846242910 scopus 로고    scopus 로고
    • Characterization of a progenitor cell population in childhood T-cell acute lymphoblastic leukemia
    • C. V. Cox H. M. Martin P. R. Kearns 2007 Characterization of a progenitor cell population in childhood T-cell acute lymphoblastic leukemia Blood 109 674 682
    • (2007) Blood , vol.109 , pp. 674-682
    • Cox, C.V.1    Martin, H.M.2    Kearns, P.R.3
  • 58
    • 21344454219 scopus 로고    scopus 로고
    • Isolation and in vitro propagation of tumorigenic breast cancer cells with stem/progenitor cell properties
    • D. Ponti A. Costa N. Zaffaroni 2005 Isolation and in vitro propagation of tumorigenic breast cancer cells with stem/progenitor cell properties Cancer Research 65 5506 5511
    • (2005) Cancer Research , vol.65 , pp. 5506-5511
    • Ponti, D.1    Costa, A.2    Zaffaroni, N.3
  • 59
  • 60
    • 35848955428 scopus 로고    scopus 로고
    • ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome
    • C. Ginestier M. H. Hur E. Charafe-Jauffret 2007 ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome Cell Stem Cell 1 555 567
    • (2007) Cell Stem Cell , vol.1 , pp. 555-567
    • Ginestier, C.1    Hur, M.H.2    Charafe-Jauffret, E.3
  • 61
    • 0141842674 scopus 로고    scopus 로고
    • Identification of a cancer stem cell in human brain tumors
    • S. K. Singh I. D. Clarke M. Terasaki 2003 Identification of a cancer stem cell in human brain tumors Cancer Research 63 5821 5828
    • (2003) Cancer Research , vol.63 , pp. 5821-5828
    • Singh, S.K.1    Clarke, I.D.2    Terasaki, M.3
  • 62
    • 9244241576 scopus 로고    scopus 로고
    • Identification of human brain tumor initiating cells
    • S. K. Singh C. Hawkins I. D. Clarke 2004 Identification of human brain tumor initiating cells Nature 432 396 401
    • (2004) Nature , vol.432 , pp. 396-401
    • Singh, S.K.1    Hawkins, C.2    Clarke, I.D.3
  • 64
    • 4944250781 scopus 로고    scopus 로고
    • Isolation and characterization of tumorigenic, stem-like neural precursors from human glioblastoma
    • R. Gali E. Binda U. Orfanelli 2004 Isolation and characterization of tumorigenic, stem-like neural precursors from human glioblastoma Cancer Research 64 7011 7021
    • (2004) Cancer Research , vol.64 , pp. 7011-7021
    • Gali, R.1    Binda, E.2    Orfanelli, U.3
  • 65
    • 11244293572 scopus 로고    scopus 로고
    • Isolation of cancer stem cells from adult glioblastoma multiforme
    • X. Yuan J. Curtin Y. Xiong 2004 Isolation of cancer stem cells from adult glioblastoma multiforme Oncogene 23 9392 9400
    • (2004) Oncogene , vol.23 , pp. 9392-9400
    • Yuan, X.1    Curtin, J.2    Xiong, Y.3
  • 66
    • 28244472369 scopus 로고    scopus 로고
    • Prospective identification of tumorigenic prostate cancer stem cells
    • A. T. Collins P. A. Berry C. Hyde 2005 Prospective identification of tumorigenic prostate cancer stem cells Cancer Research 65 10946 10951
    • (2005) Cancer Research , vol.65 , pp. 10946-10951
    • Collins, A.T.1    Berry, P.A.2    Hyde, C.3
  • 67
    • 33645026803 scopus 로고    scopus 로고
    • + prostate cancer cells from xenograft human tumors are enriched in tumorigenic and metastatic progenitor cells
    • + prostate cancer cells from xenograft human tumors are enriched in tumorigenic and metastatic progenitor cells Oncogene 25 1696 1708
    • (2006) Oncogene , vol.25 , pp. 1696-1708
    • Patrawala, L.1    Calhoun, T.2    Schneider-Broussard, R.3
  • 69
    • 34248140257 scopus 로고    scopus 로고
    • Identification of putative stem cell markers, CD133 and CXCR4, in hTERT-immortalized primary nonmalignant and malignant tumor-derived human prostate epithelial cell lines and in prostate cancer specimens
    • J. Miki B. Furusato H. Li 2007 Identification of putative stem cell markers, CD133 and CXCR4, in hTERT-immortalized primary nonmalignant and malignant tumor-derived human prostate epithelial cell lines and in prostate cancer specimens Cancer Research 67 3153 3161
    • (2007) Cancer Research , vol.67 , pp. 3153-3161
    • Miki, J.1    Furusato, B.2    Li, H.3
  • 70
    • 27144557960 scopus 로고    scopus 로고
    • A tumorigenic subpopulation with stem cell properties in melanomas
    • D. Fang T. K. Nguyen K. Leishear 2005 A tumorigenic subpopulation with stem cell properties in melanomas Cancer Research 65 9328 9337
    • (2005) Cancer Research , vol.65 , pp. 9328-9337
    • Fang, D.1    Nguyen, T.K.2    Leishear, K.3
  • 71
    • 38349165576 scopus 로고    scopus 로고
    • Identification of cells initiating human melanomas
    • T. Schatton G. F. Murphy N. Y. Frank 2008 Identification of cells initiating human melanomas Nature 451 345 352
    • (2008) Nature , vol.451 , pp. 345-352
    • Schatton, T.1    Murphy, G.F.2    Frank, N.Y.3
  • 73
    • 33847686753 scopus 로고    scopus 로고
    • CD133 positive hepatocellular carcinoma cells possess high capacity for tumorigenicity
    • S. Yin J. Li C. Hu 2007 CD133 positive hepatocellular carcinoma cells possess high capacity for tumorigenicity International Journal of Cancer 120 1436 1442
    • (2007) International Journal of Cancer , vol.120 , pp. 1436-1442
    • Yin, S.1    Li, J.2    Hu, C.3
  • 74
    • 34249980343 scopus 로고    scopus 로고
    • Identification and characterization of tumorigenic liver cancer stem/progenitor cells
    • S. Ma K. W. Chan L. Hu 2007 Identification and characterization of tumorigenic liver cancer stem/progenitor cells Gastroenterology 132 2542 2556
    • (2007) Gastroenterology , vol.132 , pp. 2542-2556
    • Ma, S.1    Chan, K.W.2    Hu, L.3
  • 75
    • 51649119918 scopus 로고    scopus 로고
    • Aldehyde dehydrogenase discriminates the CD133 liver cancer stem cell populations
    • Tang KW, Wo JY, Zheng BJ, Guan XY. (in press).
    • Ma, S., Chan, K. W., Lee, T. K., et al. (2008). Tang KW, Wo JY, Zheng BJ, Guan XY. Aldehyde dehydrogenase discriminates the CD133 liver cancer stem cell populations. Molecular Cancer Research (in press).
    • (2008) Molecular Cancer Research
    • Ma, S.1    Chan, K.W.2    Lee, T.K.3
  • 76
    • 40949160140 scopus 로고    scopus 로고
    • Identification of local and circulating cancer stem cells in human liver cancer
    • Z. F. Yang P. Ngai D. W. Ho 2008 Identification of local and circulating cancer stem cells in human liver cancer Hepatology 47 1 10
    • (2008) Hepatology , vol.47 , pp. 1-10
    • Yang, Z.F.1    Ngai, P.2    Ho, D.W.3
  • 78
    • 33846100356 scopus 로고    scopus 로고
    • A human colon cancer cell capable of initiating tumor growth in immunodeficient mice
    • C. A. O'Brien A. Pollett S. Gallinger 2007 A human colon cancer cell capable of initiating tumor growth in immunodeficient mice Nature 445 106 110
    • (2007) Nature , vol.445 , pp. 106-110
    • O'Brien, C.A.1    Pollett, A.2    Gallinger, S.3
  • 80
    • 33846095137 scopus 로고    scopus 로고
    • Identification and expansion of human colon-cancer-initiating cells
    • L. Ricci-Vitiani D. G. Lombardi E. Pilozzi 2007 Identification and expansion of human colon-cancer-initiating cells Nature 445 111 115
    • (2007) Nature , vol.445 , pp. 111-115
    • Ricci-Vitiani, L.1    Lombardi, D.G.2    Pilozzi, E.3
  • 81
    • 33847052127 scopus 로고    scopus 로고
    • Identification of pancreatic cancer stem cells
    • C. W. Li D. G. Heidt P. Dalerba 2007 Identification of pancreatic cancer stem cells Cancer Research 67 1030 1037
    • (2007) Cancer Research , vol.67 , pp. 1030-1037
    • Li, C.W.1    Heidt, D.G.2    Dalerba, P.3
  • 82
    • 34548455927 scopus 로고    scopus 로고
    • Distinct populations of cancer stem cells determine tumor growth and metastatic activity in human pancreatic cancer
    • P. C. Hermann S. L. Huber T. Herrler 2007 Distinct populations of cancer stem cells determine tumor growth and metastatic activity in human pancreatic cancer Cell Stem Cell 1 313 323
    • (2007) Cell Stem Cell , vol.1 , pp. 313-323
    • Hermann, P.C.1    Huber, S.L.2    Herrler, T.3
  • 84
    • 0029958876 scopus 로고    scopus 로고
    • Isolation and functional properties of murine hematopoietic stem cells that are replicating in vivo
    • M. A. Goodell K. Brose G. Paradis 1996 Isolation and functional properties of murine hematopoietic stem cells that are replicating in vivo Journal of Experimental Medicine 183 1797 1806
    • (1996) Journal of Experimental Medicine , vol.183 , pp. 1797-1806
    • Goodell, M.A.1    Brose, K.2    Paradis, G.3
  • 85
    • 0031435428 scopus 로고    scopus 로고
    • Dye efflux studies suggest that hematopoietic stem cells expressing low or undetectable levels of CD34 antigen exist in multiple species
    • M. A. Goodell M. Rosenzweig H. Kim 1997 Dye efflux studies suggest that hematopoietic stem cells expressing low or undetectable levels of CD34 antigen exist in multiple species Nature Medicine 3 1337 1345
    • (1997) Nature Medicine , vol.3 , pp. 1337-1345
    • Goodell, M.A.1    Rosenzweig, M.2    Kim, H.3
  • 86
    • 0036364467 scopus 로고    scopus 로고
    • Multidrug resistance in cancer: Role of ATP-dependent transporters
    • M. M. Gottesman T. Fojo S. E. Bates 2002 Multidrug resistance in cancer: role of ATP-dependent transporters Nature Review Cancer 2 48 58
    • (2002) Nature Review Cancer , vol.2 , pp. 48-58
    • Gottesman, M.M.1    Fojo, T.2    Bates, S.E.3
  • 87
    • 48349133869 scopus 로고    scopus 로고
    • Side population cells in human cancers
    • (in press).
    • Wu, C., & Alman, B. A. (2008). Side population cells in human cancers. Cancer Letter (in press).
    • (2008) Cancer Letter
    • Wu, C.1    Alman, B.A.2
  • 89
    • 0035883060 scopus 로고    scopus 로고
    • A leukemic stem cell with intrinsic drug efflux capacity in acute myeloid leukemia
    • G. G. Wulf R. Y. Wang I. Kuehnle 2001 A leukemic stem cell with intrinsic drug efflux capacity in acute myeloid leukemia Blood 98 1166 1173
    • (2001) Blood , vol.98 , pp. 1166-1173
    • Wulf, G.G.1    Wang, R.Y.2    Kuehnle, I.3
  • 92
    • 33744985294 scopus 로고    scopus 로고
    • Characterization of a side population of cancer cells from human gastrointestinal system
    • N. Haraguchi T. Utsunomiya H. Inoue 2006 Characterization of a side population of cancer cells from human gastrointestinal system Stem Cells 24 506 513
    • (2006) Stem Cells , vol.24 , pp. 506-513
    • Haraguchi, N.1    Utsunomiya, T.2    Inoue, H.3
  • 93
    • 33745924696 scopus 로고    scopus 로고
    • Side population purified from hepatocellular carcinoma cells harbors cancer stem cell-like properties
    • T. Chiba K. Kita Y. W. Zheng 2006 Side population purified from hepatocellular carcinoma cells harbors cancer stem cell-like properties Hepatology 44 240 251
    • (2006) Hepatology , vol.44 , pp. 240-251
    • Chiba, T.1    Kita, K.2    Zheng, Y.W.3
  • 95
    • 34248529666 scopus 로고    scopus 로고
    • Identification of cancer stem cell-like side population cells in human nasopharyngeal carcinoma cell line
    • J. Wang L. P. Guo L. Z. Chen 2006 Identification of cancer stem cell-like side population cells in human nasopharyngeal carcinoma cell line Cancer Research 67 3716 3724
    • (2006) Cancer Research , vol.67 , pp. 3716-3724
    • Wang, J.1    Guo, L.P.2    Chen, L.Z.3
  • 96
    • 33947427509 scopus 로고    scopus 로고
    • Characterization of side population in thyroid cancer cell lines: Cancer stem-like cells are enriched but not exclusively
    • N. Mitsutake A. Iwao K. Nagai 2007 Characterization of side population in thyroid cancer cell lines: cancer stem-like cells are enriched but not exclusively Endocrinology 148 1797 1803
    • (2007) Endocrinology , vol.148 , pp. 1797-1803
    • Mitsutake, N.1    Iwao, A.2    Nagai, K.3
  • 97
    • 34250306257 scopus 로고    scopus 로고
    • Side population in human lung cancer cell lines and tumors is enriched with stem-like cancer cells
    • M. M. Ho A. V. Ng S. Lam 2007 Side population in human lung cancer cell lines and tumors is enriched with stem-like cancer cells Cancer Research 67 4827 4833
    • (2007) Cancer Research , vol.67 , pp. 4827-4833
    • Ho, M.M.1    Ng, A.V.2    Lam, S.3
  • 98
    • 40149092373 scopus 로고    scopus 로고
    • Persistence of side population cells with high drug efflux capacity in pancreatic cancer
    • J. Zhou C. Y. Wang T. Liu 2008 Persistence of side population cells with high drug efflux capacity in pancreatic cancer World Journal of Gastroenterology 14 925 930
    • (2008) World Journal of Gastroenterology , vol.14 , pp. 925-930
    • Zhou, J.1    Wang, C.Y.2    Liu, T.3
  • 99
    • 33750313208 scopus 로고    scopus 로고
    • Cancer stem cells-perspectives on current status and future directions: AACR workshop on cancer stem cells
    • M. F. Clarke J. E. Dick P. B. Dirks 2006 Cancer stem cells-perspectives on current status and future directions: AACR workshop on cancer stem cells Cancer Research 66 9339 9344
    • (2006) Cancer Research , vol.66 , pp. 9339-9344
    • Clarke, M.F.1    Dick, J.E.2    Dirks, P.B.3
  • 100
    • 33644559031 scopus 로고    scopus 로고
    • Identifying cancer stem cells in solid tumors: Case not proven
    • R. P. Hill 2006 Identifying cancer stem cells in solid tumors: case not proven Cancer Research 66 1891 1895
    • (2006) Cancer Research , vol.66 , pp. 1891-1895
    • Hill, R.P.1
  • 101
    • 33745880104 scopus 로고    scopus 로고
    • Side population (SP) cells: Taking center stages in regeneration and liver cancer
    • S. J. Forbes M. R. Alison 2006 Side population (SP) cells: taking center stages in regeneration and liver cancer Hepatology 44 23 25
    • (2006) Hepatology , vol.44 , pp. 23-25
    • Forbes, S.J.1    Alison, M.R.2
  • 102
    • 34248547533 scopus 로고    scopus 로고
    • Most C6 cells are cancer stem cells: Evidence from clonal and population analysis
    • X. Zheng G. Shen X. Yang 2007 Most C6 cells are cancer stem cells: evidence from clonal and population analysis Cancer Research 67 3691 3697
    • (2007) Cancer Research , vol.67 , pp. 3691-3697
    • Zheng, X.1    Shen, G.2    Yang, X.3
  • 103
    • 47149111975 scopus 로고    scopus 로고
    • Expression and clinical significance of the stem cell marker CD133 in hepatocellular carcinoma
    • (in press).
    • Song, W., Li, H., Tao, K., et al. (2008). Expression and clinical significance of the stem cell marker CD133 in hepatocellular carcinoma. International Journal of Clinical Practice (in press).
    • (2008) International Journal of Clinical Practice
    • Song, W.1    Li, H.2    Tao, K.3
  • 104
    • 40749150740 scopus 로고    scopus 로고
    • CD133+HCC cancer stem cells confer chemoresistance by preferential expression of the Akt/PKB survival pathway
    • S. Ma T. K. Lee B. J. Zheng 2008 CD133+HCC cancer stem cells confer chemoresistance by preferential expression of the Akt/PKB survival pathway Oncogene 27 1749 1758
    • (2008) Oncogene , vol.27 , pp. 1749-1758
    • Ma, S.1    Lee, T.K.2    Zheng, B.J.3
  • 105
    • 0030024868 scopus 로고    scopus 로고
    • Induction of cyclophosphamide-resistance by aldehyde dehydrogenase gene transfer
    • M. Magni S. Shammah R. Schiro W. Mellado R. Dalla-Favera A. M. Gianni 1996 Induction of cyclophosphamide-resistance by aldehyde dehydrogenase gene transfer Blood 87 1097 1103
    • (1996) Blood , vol.87 , pp. 1097-1103
    • Magni, M.1    Shammah, S.2    Schiro, R.3    Mellado, W.4    Dalla-Favera, R.5    Gianni, A.M.6
  • 106
    • 20344364875 scopus 로고    scopus 로고
    • Characterization of cells with a high aldehyde dehydrogenase activity from cord blood and acute myeloid leukemia samples
    • D. J. Pearce D. Taussig C. Simpson K. Allen A. Z. Rohatiner T. A. Lister D. Bonnet 2005 Characterization of cells with a high aldehyde dehydrogenase activity from cord blood and acute myeloid leukemia samples Stem Cells 23 752 760
    • (2005) Stem Cells , vol.23 , pp. 752-760
    • Pearce, D.J.1    Taussig, D.2    Simpson, C.3    Allen, K.4    Rohatiner, A.Z.5    Lister, T.A.6    Bonnet, D.7
  • 107
    • 36348991571 scopus 로고    scopus 로고
    • Activation of hepatic stem cell marker EpCAM by Wnt-β-catenin signaling in hepatocellular carcinoma
    • T. Yamashita A. Budhu M. Forgues 2007 Activation of hepatic stem cell marker EpCAM by Wnt-β-catenin signaling in hepatocellular carcinoma Cancer Research 67 10831 10839
    • (2007) Cancer Research , vol.67 , pp. 10831-10839
    • Yamashita, T.1    Budhu, A.2    Forgues, M.3
  • 108
    • 40449099255 scopus 로고    scopus 로고
    • EpCAM and alpha-fetoprotein expression defines novel prognostic subtypes of hepatocellular carcinoma
    • T. Yamashita M. Forgues W. Wang 2008 EpCAM and alpha-fetoprotein expression defines novel prognostic subtypes of hepatocellular carcinoma Cancer Research 68 1451 1461
    • (2008) Cancer Research , vol.68 , pp. 1451-1461
    • Yamashita, T.1    Forgues, M.2    Wang, W.3
  • 109
    • 34548471937 scopus 로고    scopus 로고
    • Enhanced self-renewal capability in hepatic stem/progenitor cells drives cancer initiation
    • T. Chiba Y. W. Zheng K. Kita 2007 Enhanced self-renewal capability in hepatic stem/progenitor cells drives cancer initiation Gastroenterology 133 937 950
    • (2007) Gastroenterology , vol.133 , pp. 937-950
    • Chiba, T.1    Zheng, Y.W.2    Kita, K.3
  • 110
    • 40649116943 scopus 로고    scopus 로고
    • Progenitor/stem cells give rise to liver cancer due to aberrant TFG-β and IL-6 signaling
    • Y. Tang K. Kitisin W. Jogunoori 2008 Progenitor/stem cells give rise to liver cancer due to aberrant TFG-β and IL-6 signaling PNAS 105 2445 2450
    • (2008) PNAS , vol.105 , pp. 2445-2450
    • Tang, Y.1    Kitisin, K.2    Jogunoori, W.3
  • 111
    • 20544458318 scopus 로고    scopus 로고
    • Stem cell division is regulated by the microRNA pathway
    • S. D. Hatfield H. R. Shcherbata K. A. Fischer 2005 Stem cell division is regulated by the microRNA pathway Nature 435 974 978
    • (2005) Nature , vol.435 , pp. 974-978
    • Hatfield, S.D.1    Shcherbata, H.R.2    Fischer, K.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.