Global structural changes of an ion channel during its gating are followed by ion mobility mass spectrometry

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 48, 2014, Pages 17170-17175

  Konijnenberg, Albert ^a   Yilmaz, Duygu ^a,b   Ingólfsson, Helgi I ^b,c   Dimitrova, Anna ^b   Marrink, Siewert J ^b,c   Li, Zhuolun ^d   Vénien Bryan, Catherine ^d   Sobott, Frank ^a,e   Kocer, Armagampan ^f  

^a Biomolecular and Analytical Mass Spectrometry Group   (Canada)

^b Department of Biochemistry ^*  (Canada)

^c UNIVERSITY OF GRONINGEN   (Netherlands)

^d SORBONNE UNIVERSITÉ   (France)

^e UNIVERSITY OF ANTWERP   (Belgium)

^f UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

Author keywords

Ion channel gating; Ion mobility mass spectrometry |; Membrane proteins |; MscL |; Structure function |

Indexed keywords

ESCHERICHIA COLI;

DETERGENT; ESCHERICHIA COLI PROTEIN; ION CHANNEL; MEMBRANE PROTEIN; MSCL PROTEIN, E COLI; OCTOXINOL;

CHANNEL GATING; CHEMISTRY; ELECTRON MICROSCOPY; ESCHERICHIA COLI; MASS SPECTROMETRY; MECHANOTRANSDUCTION; METABOLISM; MOLECULAR DYNAMICS; PHYSIOLOGY; PROCEDURES; PROTEIN CONFORMATION; ULTRASTRUCTURE;

DETERGENTS; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; ION CHANNEL GATING; ION CHANNELS; MASS SPECTROMETRY; MECHANOTRANSDUCTION, CELLULAR; MEMBRANE PROTEINS; MICROSCOPY, ELECTRON; MOLECULAR DYNAMICS SIMULATION; OCTOXYNOL; PROTEIN CONFORMATION;

EID: 84914145406     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1413118111     Document Type: Article

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