Chemically charging the pore constriction opens the mechanosensitive channel MscL

Biophysical Journal

Volumn 80, Issue 5, 2001, Pages 2198-2206

  Yoshimura, Kenjiro ^a   Batiza, Ann ^b   Kung, Ching ^b  

^a UNIVERSITY OF TOKYO   (Japan)

^b UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 AMINOETHYLMETHANETHIOSULFONATE; MEMBRANE PROTEIN; MESYLIC ACID METHYL ESTER; SODIUM (2 SULFONATOETHYL)METHANETHIOSULFONATE; SULFONIC ACID DERIVATIVE; UNCLASSIFIED DRUG; [2 (TRIMETHYLAMMONIUM)ETHYL]METHANETHIOSULFONATE;

AMINO ACID SUBSTITUTION; ARTICLE; CHANNEL GATING; ESCHERICHIA COLI; HYDROPHILICITY; HYDROPHOBICITY; MEMBRANE CHANNEL; MOLECULAR DYNAMICS; STRUCTURE ACTIVITY RELATION;

EID: 0035035068     PISSN: 00063495     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-3495(01)76192-9     Document Type: Article

References (3)

1. Ajouz, B., C. Berrier, A. Garrigues, M. Besnard, and A. Ghazi. 1998. Release of thioredoxin via the mechanosensitive channel MscL during osmotic downshock of Escherichia coli cells. J. Biol. Chem. 273: 26670-26674.
2. Akabas, M. H., D. A. Stauffer, M. Xu, and A. Karlin. 1992. Acetylcholine receptor channel structure probed in cysteine-substituted mutants. Science. 258:307-310.
3. Bargmann, C. 1994. Molecular mechanisms of mechanosensation? Cell. 78:729-731.