Intravital imaging reveals distinct responses of depleting dynamic tumor-associated macrophage and dendritic cell subpopulations

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 47, 2014, Pages E5086-E5095

  Lohela, Marja ^a,c   Casbon, Amy Jo ^a   Olow, Aleksandra ^a   Bonham, Lynn ^b,d   Branstetter, Daniel ^b   Weng, Ning ^b   Smith, Jeffrey ^b   Werb, Zena ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b AMGEN INC   (United States)

^c UNIVERSITY OF HELSINKI   (Finland)

^d Department of Radiation Oncology University of California ^*  (United States)

Author keywords

Csf 1 receptor; Inflammation; Lung metastasis; Matrix metalloproteinase; Myeloid cells

Indexed keywords

BIOLOGICAL MARKER; COLONY STIMULATING FACTOR 1; COLONY STIMULATING FACTOR 1 RECEPTOR; COLONY STIMULATING FACTOR RECEPTOR; MATRIX METALLOPROTEINASE; NEUTRALIZING ANTIBODY; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIANGIOGENIC ACTIVITY; ARTICLE; BONE MARROW CELL; CANCER GROWTH; CANCER INHIBITION; CANCER MODEL; CANCER PROGNOSIS; CELL DEPLETION; CELL FUNCTION; CELL INFILTRATION; CELL INTERACTION; CELL MIGRATION; CELL SELECTION; CELL SUBPOPULATION; CELL SURVIVAL; CONFOCAL INTRAVITAL MICROSCOPY; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DENDRITIC CELL; ENDOCYTOSIS; ENZYME ACTIVITY; FEMALE; FIBROBLAST; LUNG METASTASIS; METASTASIS INHIBITION; MOUSE; NEUTROPHIL; NONHUMAN; STROMA; TUMOR ASSOCIATED LEUKOCYTE; TUMOR MICROENVIRONMENT; TUMOR VASCULARIZATION; ANIMAL; ANTAGONISTS AND INHIBITORS; CELL DIVISION; EXPERIMENTAL MAMMARY NEOPLASM; IMMUNOLOGY; LUNG TUMOR; MACROPHAGE; PATHOLOGY; SECONDARY;

MOUSE MAMMARY TUMOR VIRUS;

ANIMALS; CELL DIVISION; ENDOCYTOSIS; FEMALE; LUNG NEOPLASMS; MACROPHAGES; MAMMARY NEOPLASMS, EXPERIMENTAL; MICE; NEUTROPHILS; RECEPTOR, MACROPHAGE COLONY-STIMULATING FACTOR; TUMOR MICROENVIRONMENT;

EID: 84913553302     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1419899111     Document Type: Article

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