VCAM-1 and VAP-1 recruit myeloid cells that promote pulmonary metastasis in mice

Blood

Volumn 121, Issue 16, 2013, Pages 3289-3297

  Ferjančič, Špela ^a   Gil Bernabé, Ana M ^a   Hill, Sally A ^a   Allen, Philip D ^a   Richardson, Peter ^b   Sparey, Tim ^b   Savory, Edward ^b   McGuffog, Jane ^b   Muschel, Ruth J ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b Proximagen Group Plc   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CD11B ANTIGEN; CD18 ANTIGEN; CD45 ANTIGEN; CHEMOKINE RECEPTOR CX3CR1; CHLORDANE; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; GLYCOPROTEIN P 15095; INTERCELLULAR ADHESION MOLECULE 1; LIPOPOLYSACCHARIDE; PADGEM PROTEIN; RECOMBINANT HIRUDIN; TISSUE FACTOR PATHWAY INHIBITOR; VASCULAR ADHESION PROTEIN 1; VASCULAR CELL ADHESION MOLECULE 1; VON WILLEBRAND FACTOR; AMINE OXIDASE (COPPER CONTAINING); CELL ADHESION MOLECULE; SEMICARBAZIDE SENSITIVE AMINE OXIDASE VASCULAR ADHESION PROTEIN 1, MOUSE; SEMICARBAZIDE-SENSITIVE AMINE OXIDASE-VASCULAR ADHESION PROTEIN-1, MOUSE;

ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD CLOTTING; BONE MARROW CELL; CELL ACTIVATION; CELL ADHESION; CELL SURVIVAL; COLONY FORMATION; CONTROLLED STUDY; ENDOTHELIUM CELL; EXPERIMENTAL LUNG METASTASIS; HUMAN; HUMAN CELL; LIVER METASTASIS; LUNG BLOOD VESSEL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; TUMOR CELL; UPREGULATION; ANIMAL; BAGG ALBINO MOUSE; BLOOD; C57BL MOUSE; IMMUNOLOGY; LUNG; LUNG TUMOR; MACROPHAGE; METASTASIS; MOUSE MUTANT; PATHOLOGY; TUMOR CELL LINE;

AMINE OXIDASE (COPPER-CONTAINING); ANIMALS; BLOOD COAGULATION; CELL ADHESION; CELL ADHESION MOLECULES; CELL LINE, TUMOR; ENDOTHELIAL CELLS; HUMANS; LUNG; LUNG NEOPLASMS; MACROPHAGES; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, SCID; MYELOID CELLS; VASCULAR CELL ADHESION MOLECULE-1;

MLCS; MLOWN;

EID: 84879177512     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2012-08-449819     Document Type: Article

References (48)

1. Luster AD, Alon R, von Andrian UH. Immune cell migration in inflammation: Present and future therapeutic targets. Nat Immunol. 2005;6(12): 1182-1190.
2. Woodfin A, Voisin MB, Nourshargh S. Recent developments and complexities in neutrophil transmigration. Curr Opin Hematol. 2010;17(1): 9-17.
3. Salmi M, Jalkanen S. Homing-associated molecules CD73 and VAP-1 as targets to prevent harmful inflammations and cancer spread. FEBS Lett. 2011;585(11):1543-1550.
4. Bono P, Salmi M, Smith DJ, et al. Cloning and characterization of mouse vascular adhesion protein-1 reveals a novel molecule with enzymatic activity. J Immunol. 1998;160(11):5563-5571.
5. Salmi M, Jalkanen S. Ectoenzymes controlling leukocyte traffic. Eur J Immunol. 2012;42(2): 284-292.
6. Lalor PF, Sun PJ, Weston CJ, et al. Activation of vascular adhesion protein-1 on liver endothelium results in an NF-kappaB2dependent increase in lymphocyte adhesion. Hepatology. 2007;45(2): 465-474.
7. Jalkanen S, Karikoski M, Mercier N, et al. The oxidase activity of vascular adhesion protein-1 (VAP-1) induces endothelial E- and P-selectins and leukocyte binding. Blood. 2007;110(6): 1864-1870.
8. Stolen CM, Marttila-Ichihara F, Koskinen K, et al. Absence of the endothelial oxidase AOC3 leads to abnormal leukocyte traffic in vivo. Immunity. 2005; 22(1):105-115.
9. Koskinen K, Nevalainen S, Karikoski M, et al. VAP-12deficient mice display defects in mucosal immunity and antimicrobial responses: Implications for antiadhesive applications. J Immunol. 2007;179(9):6160-6168.
10. Weston CJ, Adams DH. Hepatic consequences of vascular adhesion protein-1 expression. J Neural Transm. 2011;118(7):1055-1064.
11. Shetty S, Bruns T, Weston CJ, et al. Recruitment mechanisms of primary and malignant B cells to the human liver. Hepatology. 2012;56(4): 1521-1531.
12. Aspinall AI, Curbishley SM, Lalor PF, et al. CX(3) CR1 and vascular adhesion protein-12dependent recruitment of CD16(1) monocytes across human liver sinusoidal endothelium. Hepatology. 2010; 51(6):2030-2039.
13. Nakao S, Noda K, Zandi S, et al. VAP-12 mediated M2 macrophage infiltration underlies IL-1b- but not VEGF-A-induced lymph- and angiogenesis. Am J Pathol. 2011;178(4): 1913-1921.
14. Varis A, Wolf M, Monni O, et al. Targets of gene amplification and overexpression at 17q in gastric cancer. Cancer Res. 2002;62(9):2625-2629.
15. Forster-Horváth C, Döme B, Paku S, et al. Loss of vascular adhesion protein-1 expression in intratumoral microvessels of human skin melanoma. Melanoma Res. 2004;14(2):135-140.
16. Irjala H, Salmi M, Alanen K, et al. Vascular adhesion protein 1 mediates binding of immunotherapeutic effector cells to tumor endothelium. J Immunol. 2001;166(11): 6937-6943.
17. Marttila-Ichihara F, Auvinen K, Elima K, et al. Vascular adhesion protein-1 enhances tumor growth by supporting recruitment of Gr-11CD11b1 myeloid cells into tumors. Cancer Res. 2009;69(19): 7875-7883.
18. Marttila-Ichihara F, Castermans K, Auvinen K, et al. Small-molecule inhibitors of vascular adhesion protein-1 reduce the accumulation of myeloid cells into tumors and attenuate tumor growth in mice. J Immunol. 2010;184(6): 3164-3173.
19. Gil-Bernabé AM, Ferjancic S, Tlalka M, et al. Recruitment of monocytes/macrophages by tissue factor-mediated coagulation is essential for metastatic cell survival and premetastatic niche establishment in mice. Blood. 2012;119(13): 3164-3175.
20. Qian B, Deng Y, Im JH, et al. A distinct macrophage population mediates metastatic breast cancer cell extravasation, establishment and growth. PLoS ONE. 2009;4(8):e6562.
21. Qian BZ, Pollard JW. Macrophage diversity enhances tumor progression and metastasis. Cell. 2010;141(1):39-51.
22. Qian BZ, Li J, Zhang H, et al. CCL2 recruits inflammatory monocytes to facilitate breasttumour metastasis. Nature. 2011;475(7355): 222-225.
23. Bevilacqua MP, Nelson RM. Endothelialleukocyte adhesion molecules in inflammation and metastasis. Thromb Haemost. 1993;70(1): 152-154.
24. Okahara H, Yagita H, Miyake K, et al. Involvement of very late activation antigen 4 (VLA-4) and vascular cell adhesion molecule 1 (VCAM-1) in tumor necrosis factor alpha enhancement of experimental metastasis. Cancer Res. 1994; 54(12):3233-3236.
25. Garofalo A, Chirivi RG, Foglieni C, et al. Involvement of the very late antigen 4 integrin on melanoma in interleukin 1-augmented experimental metastases. Cancer Res. 1995; 55(2):414-419.
26. Cardones AR, Murakami T, Hwang ST. CXCR4 enhances adhesion of B16 tumor cells to endothelial cells in vitro and in vivo via beta(1) integrin. Cancer Res. 2003;63(20):6751-6757.
27. Chen Q, Zhang XH, Massagué J. Macrophage binding to receptor VCAM-1 transmits survival signals in breast cancer cells that invade the lungs. Cancer Cell. 2011;20(4):538-549.
28. Lu X, Mu E, Wei Y, et al. VCAM-1 promotes osteolytic expansion of indolent bone micrometastasis of breast cancer by engaging a4b1-positive osteoclast progenitors. Cancer Cell. 2011;20(6):701-714.
29. Khatib AM, Auguste P, Fallavollita L, et al. Characterization of the host proinflammatory response to tumor cells during the initial stages of livermetastasis. Am J Pathol. 2005;167(3):749-759.
30. Serres S, Soto MS, Hamilton A, et al. Molecular MRI enables early and sensitive detection of brain metastases. Proc Natl Acad Sci U S A. 2012; 109(17):6674-6679.
31. Im JH, Fu W, Wang H, et al. Coagulation facilitates tumor cell spreading in the pulmonary vasculature during early metastatic colony formation. Cancer Res. 2004;64(23):8613-8619.
32. Amirkhosravi A, Meyer T, Chang JY, et al. Tissue factor pathway inhibitor reduces experimental lung metastasis of B16 melanoma. Thromb Haemost. 2002;87(6):930-936.
33. Jung S, Aliberti J, Graemmel P, et al. Analysis of fractalkine receptor CX(3)CR1 function by targeted deletion and green fluorescent protein reporter gene insertion. Mol Cell Biol. 2000; 20(11):4106-4114.
34. Coxon A, Rieu P, Barkalow FJ, et al. A novel role for the beta 2 integrin CD11b/CD18 in neutrophil apoptosis: A homeostatic mechanism in inflammation. Immunity. 1996;5(6):653-666.
35. Esumi N, Fan D, Fidler IJ. Inhibition of murine melanoma experimental metastasis by recombinant desulfatohirudin, a highly specific thrombin inhibitor. Cancer Res. 1991;51(17): 4549-4556.
36. Schumacker PT, Samsel RW. Analysis of oxygen delivery and uptake relationships in the Krogh tissue model. J Appl Physiol. 1989;67(3): 1234-1244.
37. Bunt SK, Sinha P, Clements VK, et al. Inflammation induces myeloid-derived suppressor cells that facilitate tumor progression. J Immunol. 2006;176(1):284-290.
38. Petty JM, Lenox CC, Weiss DJ, et al. Crosstalk between CXCR4/stromal derived factor-1 and VLA-4/VCAM-1 pathways regulates neutrophil retention in the bone marrow. J Immunol. 2009; 182(1):604-612.
39. Gay LJ, Felding-Habermann B. Contribution of platelets to tumour metastasis. Nat Rev Cancer. 2011;11(2):123-134.
40. Läubli H, Borsig L. Selectins as mediators of lung metastasis. Cancer Microenviron. 2010;3(1): 97-105.
41. Brodt P, Fallavollita L, Bresalier RS, et al. Liver endothelial E-selectin mediates carcinoma cell adhesion and promotes liver metastasis. Int J Cancer. 1997;71(4):612-619.
42. Khatib AM, Fallavollita L, Wancewicz EV, et al. Inhibition of hepatic endothelial E-selectin expression by C-raf antisense oligonucleotides blocks colorectal carcinoma liver metastasis. Cancer Res. 2002;62(19):5393-5398.
43. Chantrathammachart P, Mackman N, Sparkenbaugh E, et al. Tissue factor promotes activation of coagulation and inflammation in a mouse model of sickle cell disease. Blood. 2012;120(3):636-646.
44. Guo Y, Field J, Foster T, Scott JP, Wandersee N, Hillery CA. Low molecular weight heparin reduces sVCAM-1 and lung congestion in a murine model of sickle cell disease [abstract]. Blood. 2010; 116(21):1635a. Abstract 1635.
45. Singh B, Tschernig T, van Griensven M, et al. Expression of vascular adhesion protein-1 in normal and inflamed mice lungs and normal human lungs. Virchows Arch. 2003;442(5): 491-495.
46. Flick MJ, LaJeunesse CM, Talmage KE, et al. Fibrin(ogen) exacerbates inflammatory joint disease through a mechanism linked to the integrin alphaMbeta2 binding motif. J Clin Invest. 2007;117(11):3224-3235.
47. Pluskota E, Soloviev DA, Bdeir K, et al. Integrin alphaMbeta2 orchestrates and accelerates plasminogen activation and fibrinolysis by neutrophils. J Biol Chem. 2004;279(17): 18063-18072.
48. Marttila-Ichihara F, Smith DJ, Stolen C, et al. Vascular amine oxidases are needed for leukocyte extravasation into inflamed joints in vivo. Arthritis Rheum. 2006;54(9): 2852-2862.