The involvement of mitochondrial apoptotic pathway in eugenol-induced cell death in human glioblastoma cells

Toxicology Letters

Volumn 232, Issue 1, 2015, Pages 122-132

  Liang, Wei Zhe ^a   Chou, Chiang Ting ^b   Hsu, Shu Shong ^a,c   Liao, Wei Chuan ^c   Shieh, Pochuen ^d   Kuo, Daih Huang ^d   Tseng, Hui Wen ^a   Kuo, Chun Chi ^e   Jan, Chung Ren ^a  

^a KAOHSIUNG VETERANS GENERAL HOSPITAL   (Taiwan)

^b CHANG GUNG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Taiwan)

^c NATIONAL DEFENSE MEDICAL CENTER   (Taiwan)

^d TAJEN UNIVERSITY   (Taiwan)

^e TZU HUI INSTITUTE OF TECHNOLOGY   (Taiwan)

Author keywords

Apoptosis; Ca2+; Eugenol; Human glioblastoma cells; TRPM8

Indexed keywords

1 [[6 (3 METHOXYESTRA 1,3,5(10) TRIEN 17BETA YL)AMINO]HEXYL] 1H PYRROLE 2,5 DIONE; 2,5 DI TERT BUTYLHYDROQUINONE; CALCIUM CHANNEL BLOCKING AGENT; CALCIUM ION; CAPSAZEPINE; CASPASE 3; CASPASE 9; CYTOCHROME C; ETHYLENE GLYCOL 1,2 BIS(2 AMINOPHENYL) ETHER N,N,N',N' TETRAACETIC ACID; EUGENOL; GF109203X; MANGANESE; PROTEIN KINASE C INHIBITOR; REACTIVE OXYGEN METABOLITE; THAPSIGARGIN; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; APOPTOSIS REGULATORY PROTEIN; PHOSPHOLIPASE C; PROTEIN KINASE C; TRANSIENT RECEPTOR POTENTIAL CHANNEL M; TRPM8 PROTEIN, HUMAN;

APOPTOSIS; ARTICLE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CELL DEATH; CELL KILLING; CHELATION; CONTROLLED STUDY; CYTOTOXICITY; DBTRG 05MG CELL; ENDOPLASMIC RETICULUM; ENZYME RELEASE; EXTRACELLULAR CALCIUM; GLIOBLASTOMA CELL LINE; HUMAN; HUMAN CELL; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; PROTEIN CLEAVAGE; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; BRAIN NEOPLASMS; CALCIUM SIGNALING; DOSE RESPONSE; DRUG EFFECTS; GLIOBLASTOMA; METABOLISM; PATHOLOGY; TIME FACTOR; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; BRAIN NEOPLASMS; CALCIUM SIGNALING; CELL LINE, TUMOR; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOPLASMIC RETICULUM; EUGENOL; GLIOBLASTOMA; HUMANS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA; PROTEIN KINASE C; REACTIVE OXYGEN SPECIES; TIME FACTORS; TRPM CATION CHANNELS; TYPE C PHOSPHOLIPASES;

EID: 84913528877     PISSN: 03784274     EISSN: 18793169     Source Type: Journal    
DOI: 10.1016/j.toxlet.2014.10.023     Document Type: Article

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