Neuroprotective efficacy of eugenol and isoeugenol in acrylamide-induced neuropathy in rats: Behavioral and biochemical evidence

Neurochemical Research

Volumn 38, Issue 2, 2013, Pages 330-345

  Prasad, Sathya N ^a   Muralidhara, ^a  

^a CENTRAL FOOD TECHNOLOGICAL RESEARCH INSTITUTE   (India)

Author keywords

Acrylamide; Eugenol; Isoeugenol; Neuropathy; Oxidative stress; Sciatic nerve

Indexed keywords

ACETYLCHOLINESTERASE; ACRYLAMIDE; ADENOSINE TRIPHOSPHATASE; CALCIUM; DOPAMINE; EUGENOL; GLUTATHIONE; ISOEUGENOL; MALONALDEHYDE; NITRIC OXIDE; REACTIVE OXYGEN METABOLITE;

ANIMAL BEHAVIOR; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; BRAIN CORTEX; BRAIN REGION; CEREBELLUM; CHEMICAL ANALYSIS; CONTROLLED STUDY; CYTOSOL; DOPAMINE METABOLISM; DRUG EFFICACY; ENZYME ACTIVITY; GAIT; MALE; MOLECULAR MECHANICS; NEUROPATHY; NEUROPROTECTION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; SCIATIC NERVE; SPICE;

ACRYLAMIDE; ANIMALS; EUGENOL; GAIT; MALE; NEURALGIA; NEUROPROTECTIVE AGENTS; PAIN MEASUREMENT; RANDOM ALLOCATION; RATS; RATS, WISTAR; TREATMENT OUTCOME;

RATTUS;

EID: 84875344605     PISSN: 03643190     EISSN: 15736903     Source Type: Journal    
DOI: 10.1007/s11064-012-0924-9     Document Type: Article

References (67)

1. Hidalgo ME, De la Rosa C (2009) Antioxidant capacity of eugenol derivatives. Quim Nova 32:1467-1470
2. Choi YC, Park KR, Lee JH et al (2007) Isoeugenol suppression of inducible nitric oxide synthase expression is mediated by down regulation of NF-kB, ERK1/2 and p38 kinase. Eur J Pharmacol 576:151-159
3. Mahapatra SK, Chakraborty SP, Majumdar S et al (2009) Eugenol protects nicotine induced superoxide mediated oxidative damage in murine peritoneal macrophages in vitro. Eur J Pharmacol 623:132-140
4. Prasad SN, Raghavendra R, Lokesh BR et al (2004) Spice phenolics inhibit human PMNL 5-lipoxygenase. Prostaglandins Leukot Essent Fat Acids 70:521-528
5. Wie MB, Won MH, Lee KH et al (1997) Eugenol neuronal cells from excitotoxic and oxidative injury in primary cortical cultures. Neurosci Lett 225:93-96
6. Kabuto H, Tada M, Kohno M (2007) Eugenol [2-methoxy-4-(2-propenyl) phenol] prevents 6-hydroxydopamine induced dopamine depression and lipid peroxidation inductivity in mouse straitum. Biol Pharm Bull 30:423-427
7. Baskaran Y, Vishwanathan P, Anuradha CV (2010) Investigation of antioxidant, anti-inflammatory and DNA-protective properties of eugenol in thioacetamide-induced liver injury in rats. Toxicology 268:204-212
8. Tardiff RG, Gargas ML, Kirman CR et al (2010) Estimation of safe dietary intake levels of acrylamide for humans. Food Chem Toxicol 48:658-667
9. Yener Y, Kalipci E (2009) The carcinogenic effects of acrylamide formed during cooking of some foods. Acad J Cancer Res 2:25-32
10. LoPachin RM, Gavin T (2008) Acrylamide induced nerve terminal damage: relevance to neurotoxic and neurodegenerative mechanisms. J Agric Food Chem 56:5994-6003
11. Tareke E, Rydberg P, Karlsson P et al (2002) Analysis of acrylamide, a carcinogen formed in food-stuffs. J Agric Food Chem 50:4998-5006
12. Sumner SC, Williams CC, Snyder RW (2003) Acrylamide: a comparison of metabolism and hemoglobin adducts in rodents following dermal, intraperitoneal, oral, or inhalation exposure. Toxicol Sci 75:260-270
13. Dybing E, Farmer PB, Anderson M et al (2005) Human exposure and internal dose assessments of acrylamide in food. Food Chem Toxicol 43:365-410
14. Zhu YJ, Zeng T, Zhu YB et al (2008) Effects of acrylamide on the nervous tissue antioxidant system and sciatic nerve electrophysiology in the rat. Neurochem Res 33:2310-2317
15. Ghareeb DA, Khalil ACR, Elbassoumy AM et al (2010) Ameliorated effects of garlic (Allium sativum) on biomarkers of subchronic acrylamide hepatotoxicity and brain toxicity in rats. Toxicol Environ Chem 92:1357-1372
16. Cook LEL Jr, Tareke E, Word B et al (2011) Food contaminant acrylamide increase expression of Cox-2 and nitric oxide synthase in breast epithelial cells. Toxicol Ind Health 27:11-18
17. Lim TG, Lee BK, Kwon JY et al (2011) Acrylamide up-regulates cyclooxygenase-2 expression through the MEK/ERK signalling pathway in mouse epidermal cells. Food Chem Toxicol 49:1254-1259
18. Lehning EJ, Balaban CD, Ross JF et al (2002) Acrylamide neuropathy: I. Spatiotemporal characteristics of nerve cell damage in rat cerebellum. NeuroToxicology 23:397-414
19. LoPachin RM, Balaban CD, Ross JF (2003) Acrylamide axonopathy revisited. Toxicol Appl Pharmacol 188:135-153
20. Ling B, Authier N, Balayssac D et al (2005) Assessment of nociception in acrylamide-induced neuropathy in rats. Pain 119:104-112
21. Yu S, Son F, Yu J et al (2006) Acrylamide alters cytoskeletal protein in sciatic nerve. Neurochem Res 31:1197-1204
22. Xie Q, Liu Y, Sun H et al (2008) Inhibition of acrylamide toxicity in mice by three dietary constituents. J Agric Food Chem 56:6054-6060
23. Aggarwal BB, Shishodia S (2004) Suppression of the nuclear factor- kB activation pathway by spice derived phytochemicals. Ann NY Acad Sci 1030:434-441
24. Hosamani R, Muralidhara (2009) Neuroprotective efficacy of Bacopa monnieri against rotenone induced oxidative stress and neurotoxicity in Drosophila melanogaster. NeuroToxicology 30:977-985
25. Girish C, Muralidhara (2012) Propensity of Selaginella delicatula aqueous extract to offset rotenone-induced oxidative dysfunctions and neurotoxicity in Drosophila melanogaster: implications for Parkinson's disease. NeuroToxicology 33:444-456
26. Prasad SN, Muralidhara (2012) Evidence of acrylamide induced oxidative stress and neurotoxicity in Drosophila melanogaster: its amelioration with spice active enrichment: relevance to neuropathy. NeuroToxicology 33:1254-1264
27. Shinomol GK, Bharath MMS, Muralidhara (2012) Neuromodulatory propensity of Bacopa monnieri leaf extract against 3-nitropopionic acid induced oxidative stress: in vitro and in vivo evidences. Neurotox Res 22:102-114
28. Ohkawa H, Ohnishi N, Yagi K (1979) Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal Biochem 9:351-358
29. Pradat PF, Kennel P, Sadaqui SN et al (2001) Continuous delivery of neurotrophin 3by gene therapy has a neuroprotective effect in experimental models of diabetic and acrylamide neuropathies. Hum Gene Ther 12:2237-2249
30. Kanan SA, SACRdé NE, Haddad JJ et al (1996) Endotoxin induced local inflammation and hyperalgesia in rats and mice: a new model of inflammatory pain. Pain 66:373-379
31. Edwards PM, Parker VH (1977) A simple, sensitive and objective method for early assessment of acrylamide neuropathy in rats. Toxicol Appl Pharmacol 40:589-591
32. Sandhir R, Mehrotra A, Kamboj SS (2010) Lycopene prevents 3-nitropropionic acid induced mitochondrial oxidative stress and dysfunctions in nervous system. Neurochem Int 57:579-587
33. Moreadith RW, Fiskum J (1984) Isolation of mitochondria from ascites tumor cells permeabilized with digitonin. Anal Biochem 137:360-367
34. Muthuraman A, Diwan V, Jaggi AS et al (2008) Ameliorative effects of Ocimim sanctum in sciatic nerve transection induced neuropathy in rats. Eur J Pharmacol 587:104-111
35. Shinomol GK, Muralidhara (2008) Prophylactic neuroprotective property of Centella asiatica against 3-nitropropionic acid induced oxidative stress and mitochondrial dysfunctions in brain regions of prepubertal mice. NeuroToxicology 29:948-957
36. Wolf SP (1994) Ferrous ion oxidation in presence of ferric ion indicator xylenol orange for measurement of hydroperoxides. Methods Enzymol 233:182-189
37. Aebi H (1984) Catalase in vitro. Methods Enzymol 105:121-126
38. Kostyuk VA, Potapovich AI (1989) Superoxide driven oxidation of quercetin and a simple sensitive assay for determination of superoxide dismutase. Biochem Int 19:1117-1124
39. Guthenberg C, Alin P, Mannervik B (1985) Glutathione transferase from rat testis. Methods Enzymol 113:507-510
40. Mokrasch LC, Teschke EJ (1984) Glutathione content of cultured cells and rodent brain regions: a specific fluorimetric assay. Anal Biochem 140:506-509
41. Ellmann GE, Courtney KD, Andersen V et al (1961) A new and rapid colorimetric determination. Biochem Pharmacol 13:205-208
42. Desaiah D, Phillips TD, Hayes AW et al (1979) Effect of aflatoxins on ATPase activities on mouse and rat liver. J Environ Sci Health B 14:265-278
43. Fiske CH, Subbarow YJ (1925) The colorimetric determination of phosphorous. J Biol Chem 66:375-381
44. Hitoshi A, Satoh T, Sakai N et al (1997) Generation of free radicals during lipid peroxide triggered apoptosis in PC 12 cells. Biochim Biophys Acta 1345:35-42
45. Dalpiaz A, Filosa K, de Caprariis P et al (2007) Molecular mechanism involved in the transport of a prodrug dopamine glycosyl conjugate. Int J Pharm 336:133-139
46. Lowry OH, Rosenbrough NJ, Farr AL et al (1951) Protein measurements using folin-phenol reagent. J Biol Chem 193:265-275
47. Kumar A, Kaundal RK, Iyer S et al (2007) Effects of resveratrol on nerve functions, oxidative stress and DNA fragmentation in experimental diabetic neuropathy. Life Sci 80:1236-1244
48. Kannappan R, Gupta SC, Kim JH et al (2011) Neuroprotection by spice derived nutraceuticals: you are what you eat? Mol Neurobiol 44:142-159
49. Gulcin I, Sat IG, Beydemir S et al (2004) Comparison of antioxidant activity Clove (Eugenia caryophylata Thunb) buds lavender. Food Chem 87:393-400
50. Lakshmi D, Gopinath K, Jayanthy G et al (2012) Ameliorating effect of fish oil on acrylamide induced oxidative stress and neuronal apoptosis in cerebral cortex. Neurochem Res 37:1859-1867
51. Khatun M, Eguchi S, Yamaguchi T et al (2006) Effect of Thermal Treatment on Radical-scavenging Activity of Some Spices. Food Sci Technol Res 12:178-185
52. Naziroglu M (2011) TRPM2 Cation channels, oxidative stress and neurological diseases: where are we now? Neurochem Res 36:355-366
53. Miller BA (2006) The role of TRP channels in oxidative stress-induced cell death. J Membr Biol 209:31-41
54. Kang KS, Yamabe N, Kim HY et al (2008) Therapeutic potential of 20(S)-ginsenoside Rg3 against streptozotocin-induced diabetic renal damage in rats. Eur J Pharmacol 591:266-272
55. 2+ Signaling on Molecular Pathways of Neuropathic Pain in Diabetes: focus on TRP Channels. Neurochem Res 37:2065-2075
56. Schmatz R, Mazzanti CM, Spanevello R et al (2009) Resveratrol prevents memory deficits and the increase in acetylcholinesterase activity in streptozotocin-induced diabetic rats. Eur J Pharmacol 610:42-48
57. Chacon MA, Reyes AE, Inestrosa NC (2003) Acetylcholinesterase induces neuronal cell loss, astrocyte hypertrophy and behavioural deficits in mammalian hippocampus. J Neurochem 87:195-204
58. Bernhardi RV, Alarcon R, Mezzano D et al (2005) Blood cells cholinesterase activity in early Alzeimer's disease and vascular dementia. Dement Geriatr Cogn Disord 19:204-212
59. Jin QH, He HY, Shi YF et al (2004) Overexpression of acetylchoinesterase inhibited cell proliferation and promoted apoptosis in NRK cells. Acta Pharmacol Sin 25:1013-1021
60. Sabri MI, Spencer PS (2002) How does acrylamide perturb axon transport and induce nerve fiber degeration? Commentary on forum position paper. NeuroToxicology 23:259-263
61. Martyniuk CJ, Fang B, Koomen JM et al (2011) Molecular mechanism of Glyceraldehyde 3 phosphate dehydrogenase inactivation by α β unsaturated carbonyl deriavtives. Chem Res Toxicol 24:2302-2311
62. Zhang L, Gavin T, Barber DS et al (2011) Role of Nrf2-ARE pathway in acrylamide neurotoxicity. Toxicol Lett 205:1-7
63. Glass JD, Culver DG, Levey AI et al (2002) Very early activation of m-calpain in peripheral nerve during Wallerian degeneration. J Neurol Sci 196:9-20
64. LoPachin RM (2004) The changing view of acrylamide neurotoxicity. NeuroToxicology 25:617-630
65. LoPachin RM, Schwarcz AI, Gaughan CL et al (2004) In vivo and in vitro effects of acrylamide on synaptosomal neurotransmitter uptake in rat striatal synaptic vesicles. NeuroToxicology 25:349-363
66. LoPachin RM, Barber DS, He D et al (2006) Acrylamide inhibits dopamine uptake in rat striatal synaptic vesicles. Toxicol Sci 89:224-234
67. Tareke E, Lyn-Cook BD, Duhart H et al (2009) Acrylamide decreased dopamine levels and increased 3-nitrotyrosine (3-NT) levels in PC 12 cells. Neurosci Lett 458:89-92