Menthol derivative WS-12 selectively activates transient receptor potential melastatin-8 (TRPM8) ion channels

Pakistan Journal of Pharmaceutical Sciences

Volumn 21, Issue 4, 2008, Pages 370-378

  Sherkheli, M A ^a   Gisselmann, G ^a   Vogt Eisele, A K ^a   Doerner, J F ^a   Hatt, H ^a  

^a RUHR UNIVERSITY BOCHUM   (Germany)

Author keywords

Menthol; Neuropathic analgesia; TRPM8 specific ligand; WS 12; Xenopus laevis oocytes

Indexed keywords

1 (2 HYDROXYPHENYL) 4 (3 NITROPHENYL) 1,2,3,6 TETRAHYDROPYRIMIDIN 2 ONE; ANALGESIC AGENT; ANILIDE; CALCIUM; CALCIUM CHANNEL; DRUG DERIVATIVE; MENTHOL; N (4 METHOXYPHENYL) 4 MENTHONE 3 CARBOXAMIDE; N-(4-METHOXYPHENYL)-4-MENTHONE-3-CARBOXAMIDE; NERVE PROTEIN; PYRIMIDINONE DERIVATIVE; TRANSIENT RECEPTOR POTENTIAL CHANNEL; TRANSIENT RECEPTOR POTENTIAL CHANNEL M; TRPA1 PROTEIN, HUMAN; TRPM8 PROTEIN, MOUSE; TRPV3 PROTEIN, MOUSE; UNCLASSIFIED DRUG; VANILLOID RECEPTOR;

ANIMAL; ARTICLE; CELL MEMBRANE POTENTIAL; DOSE RESPONSE; DRUG POTENTIATION; GENE TRANSFER; HUMAN; METABOLISM; MOUSE; PH; RAT; TACHYPHYLAXIS; XENOPUS LAEVIS;

ANALGESICS; ANILIDES; ANIMALS; CALCIUM; CALCIUM CHANNELS; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE TRANSFER TECHNIQUES; HUMANS; HYDROGEN-ION CONCENTRATION; MEMBRANE POTENTIALS; MENTHOL; MICE; NERVE TISSUE PROTEINS; PYRIMIDINONES; RATS; TACHYPHYLAXIS; TRANSIENT RECEPTOR POTENTIAL CHANNELS; TRPM CATION CHANNELS; TRPV CATION CHANNELS; XENOPUS LAEVIS;

EID: 58149286598     PISSN: 1011601X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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