Proprotein convertase FURIN constrains Th2 differentiation and is critical for host resistance against Toxoplasma gondii

Journal of Immunology

Volumn 193, Issue 11, 2014, Pages 5470-5479

  Oksanen, Anna ^a   Aittomäki, Saara ^a   Jankovic, Dragana ^b   Ortutay, Zsuzsanna ^a   Pulkkinen, Kati ^a   Hämäläinen, Sanna ^a   Rokka, Anne ^c   Corthals, Garry L ^c,d   Watford, Wendy T ^e,f   Junttila, Ilkka ^a,g   O'Shea, John J ^e   Pesu, Marko ^a,g  

^a TAMPERE UNIVERSITY OF TECHNOLOGY   (Finland)

^b NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^c UNIVERSITY OF TURKU   (Finland)

^d UNIVERSITY OF AMSTERDAM   (Netherlands)

^e NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES   (United States)

^f UNIVERSITY OF GEORGIA   (United States)

^g PIRKANMAA HOSPITAL DISTRICT   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

F ACTIN; FURIN; INTERLEUKIN 12; INTERLEUKIN 13; TRANSCRIPTION FACTOR FOXP3; TRANSCRIPTION FACTOR GATA 3; ACTIN; CYTOKINE; DOCK2 PROTEIN, HUMAN; GUANINE NUCLEOTIDE EXCHANGE FACTOR; PROTEIN BINDING; RAC1 PROTEIN; STAT4 PROTEIN; STAT6 PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOSKELETON; FLOW CYTOMETRY; HOST RESISTANCE; HUMAN; HUMAN CELL; IMMUNOLOGICAL TOLERANCE; IMMUNOPRECIPITATION; IN VITRO STUDY; IN VIVO STUDY; LYMPHOCYTE DIFFERENTIATION; MOUSE; NONHUMAN; POLARIZATION; POLYMERIZATION; PROTEIN ANALYSIS; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN PURIFICATION; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TH1 TH2 BALANCE; TH2 CELL; TOXOPLASMA GONDII; TOXOPLASMOSIS; CELL DIFFERENTIATION; GENETICS; IMMUNITY; IMMUNOLOGY; JURKAT CELL LINE; METABOLISM; TH1 CELL; TOXOPLASMA;

ACTINS; CELL DIFFERENTIATION; CYTOKINES; FURIN; GUANINE NUCLEOTIDE EXCHANGE FACTORS; HUMANS; IMMUNE TOLERANCE; IMMUNITY; JURKAT CELLS; PROTEIN BINDING; RAC1 GTP-BINDING PROTEIN; SIGNAL TRANSDUCTION; STAT4 TRANSCRIPTION FACTOR; STAT6 TRANSCRIPTION FACTOR; TH1 CELLS; TH2 CELLS; TOXOPLASMA; TOXOPLASMOSIS;

EID: 84912553321     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1401629     Document Type: Article

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