-
1
-
-
84856110886
-
Berberine induces heme oxygenase-1 up-regulation through phosphatidylinositol 3-kinase/AKT and NF-E2-related factor-2 signaling pathway in astrocytes
-
Chen, J. H., Huang, S. M., Tan, T. W., Lin, H. Y., Chen, P. Y., Yeh, W. L., Chou, S. C., Tsai, C. F., Wei, I. H. and Lu, D. Y. (2012) Berberine induces heme oxygenase-1 up-regulation through phosphatidylinositol 3-kinase/AKT and NF-E2-related factor-2 signaling pathway in astrocytes. Int. Immunopharmacol. 12, 94-100.
-
(2012)
Int. Immunopharmacol
, vol.12
, pp. 94-100
-
-
Chen, J.H.1
Huang, S.M.2
Tan, T.W.3
Lin, H.Y.4
Chen, P.Y.5
Yeh, W.L.6
Chou, S.C.7
Tsai, C.F.8
Wei, I.H.9
Lu, D.Y.10
-
2
-
-
4143102621
-
Arctigenin, a phenylpropanoid dibenzylbutyrolactone lignan, inhibits MAP kinases and AP-1 activation via potent MKK inhibition: The role in TNF-alpha inhibition
-
Cho, M. K., Jang, Y. P., Kim, Y. C. and Kim, S. G. (2004) Arctigenin, a phenylpropanoid dibenzylbutyrolactone lignan, inhibits MAP kinases and AP-1 activation via potent MKK inhibition: the role in TNF-alpha inhibition. Int. Immunopharmacol. 4, 1419-1429.
-
(2004)
Int. Immunopharmacol
, vol.4
, pp. 1419-1429
-
-
Cho, M.K.1
Jang, Y.P.2
Kim, Y.C.3
Kim, S.G.4
-
3
-
-
84886843302
-
How do astrocytes shape synaptic transmission? Insights from electrophysiology
-
Dallerac, G., Chever, O. and Rouach, N. (2013) How do astrocytes shape synaptic transmission? Insights from electrophysiology. Front. Cell. Neurosci. 7, 159.
-
(2013)
Front. Cell. Neurosci
, vol.7
, pp. 159
-
-
Dallerac, G.1
Chever, O.2
Rouach, N.3
-
4
-
-
54349124273
-
Nrf2-induced antioxidant protection: A promising target to counteract ROS-mediated damage in neurodegenerative disease? Free Radic
-
de Vries, H. E., Witte, M., Hondius, D., Rozemuller, A. J., Drukarch, B., Hoozemans, J. and van Horssen, J. (2008) Nrf2-induced antioxidant protection: a promising target to counteract ROS-mediated damage in neurodegenerative disease? Free Radic. Biol. Med. 45, 1375-1383.
-
(2008)
Biol. Med
, vol.45
, pp. 1375-1383
-
-
de Vries, H.E.1
Witte, M.2
Hondius, D.3
Rozemuller, A.J.4
Drukarch, B.5
Hoozemans, J.6
van Horssen, J.7
-
5
-
-
84869229018
-
Arctigenin protects focal cerebral ischemia-reperfusion rats through inhibiting neuroinflammation
-
Fan, T., Jiang, W. L., Zhu, J. and Feng Zhang, Y. (2012) Arctigenin protects focal cerebral ischemia-reperfusion rats through inhibiting neuroinflammation. Biol. Pharm. Bull. 35, 2004-2009.
-
(2012)
Biol. Pharm. Bull
, vol.35
, pp. 2004-2009
-
-
Fan, T.1
Jiang, W.L.2
Zhu, J.3
Feng Zhang, Y.4
-
6
-
-
84862558716
-
Arctigenin, a natural compound, activates AMP-activated protein kinase via inhibition of mitochondria complex I and ameliorates metabolic disorders in ob/ob mice
-
Huang, S. L., Yu, R. T., Gong, J., Feng, Y., Dai, Y. L., Hu, F., Hu, Y. H., Tao, Y. D. and Leng, Y. (2012) Arctigenin, a natural compound, activates AMP-activated protein kinase via inhibition of mitochondria complex I and ameliorates metabolic disorders in ob/ob mice. Diabetologia 55, 1469-1481.
-
(2012)
Diabetologia
, vol.55
, pp. 1469-1481
-
-
Huang, S.L.1
Yu, R.T.2
Gong, J.3
Feng, Y.4
Dai, Y.L.5
Hu, F.6
Hu, Y.H.7
Tao, Y.D.8
Leng, Y.9
-
7
-
-
84877814354
-
Arctigenin ameliorates inflammation in vitro and in vivo by inhibiting the PI3K/AKT pathway and polarizing M1 macrophages to M2-like macrophages
-
Hyam, S. R., Lee, I. A., Gu, W., Kim, K. A., Jeong, J. J., Jang, S. E., Han, M. J. and Kim, D. H. (2013) Arctigenin ameliorates inflammation in vitro and in vivo by inhibiting the PI3K/AKT pathway and polarizing M1 macrophages to M2-like macrophages. Eur. J. Pharmacol. 708, 21-29.
-
(2013)
Eur. J. Pharmacol
, vol.708
, pp. 21-29
-
-
Hyam, S.R.1
Lee, I.A.2
Gu, W.3
Kim, K.A.4
Jeong, J.J.5
Jang, S.E.6
Han, M.J.7
Kim, D.H.8
-
8
-
-
0036213741
-
Arctigenin protects cultured cortical neurons from glutamate-induced neurodegeneration by binding to kainate receptor
-
Jang, Y. P., Kim, S. R., Choi, Y. H., Kim, J., Kim, S. G., Markelonis, G. J., Oh, T. H. and Kim, Y. C. (2002) Arctigenin protects cultured cortical neurons from glutamate-induced neurodegeneration by binding to kainate receptor. J. Neurosci. Res. 68, 233-240.
-
(2002)
J. Neurosci. Res
, vol.68
, pp. 233-240
-
-
Jang, Y.P.1
Kim, S.R.2
Choi, Y.H.3
Kim, J.4
Kim, S.G.5
Markelonis, G.J.6
Oh, T.H.7
Kim, Y.C.8
-
9
-
-
78649993974
-
Anti-inflammatory mechanism of ginsenoside Rh1 in lipopolysaccharide- stimulated microglia: Critical role of the protein kinase A pathway and hemeoxygenase-1 expression
-
Jung, J. S., Shin, J. A., Park, E. M., Lee, J. E., Kang, Y. S., Min, S. W., Kim, D. H., Hyun, J. W., Shin, C. Y. and Kim, H. S. (2010) Anti-inflammatory mechanism of ginsenoside Rh1 in lipopolysaccharide- stimulated microglia: critical role of the protein kinase A pathway and hemeoxygenase-1 expression. J. Neurochem. 115, 1668-1680.
-
(2010)
J. Neurochem
, vol.115
, pp. 1668-1680
-
-
Jung, J.S.1
Shin, J.A.2
Park, E.M.3
Lee, J.E.4
Kang, Y.S.5
Min, S.W.6
Kim, D.H.7
Hyun, J.W.8
Shin, C.Y.9
Kim, H.S.10
-
10
-
-
84860390738
-
Arctigenin inhibits lipopolysaccharide-induced iNOS expression in RAW264.7 cells through suppressing JAK-STAT signal pathway
-
Kou, X., Qi, S., Dai, W., Luo, L. and Yin, Z. (2011) Arctigenin inhibits lipopolysaccharide-induced iNOS expression in RAW264.7 cells through suppressing JAK-STAT signal pathway. Int. Immunopharmacol. 11, 1095-1102.
-
(2011)
Int. Immunopharmacol
, vol.11
, pp. 1095-1102
-
-
Kou, X.1
Qi, S.2
Dai, W.3
Luo, L.4
Yin, Z.5
-
11
-
-
79952620639
-
Inhibitory mechanism of MMP-9 gene expression by ethyl pyruvate in lipopolysaccharide-stimulated BV2 microglial cells
-
Lee, E. J. and Kim, H. S. (2011) Inhibitory mechanism of MMP-9 gene expression by ethyl pyruvate in lipopolysaccharide-stimulated BV2 microglial cells. Neurosci. Lett. 493, 38-43.
-
(2011)
Neurosci. Lett
, vol.493
, pp. 38-43
-
-
Lee, E.J.1
Kim, H.S.2
-
12
-
-
21744445077
-
Nrf2, a multi-organ protector?
-
Lee, J. M., Li, J., Johnson, D. A., Stein, T. D., Kraft, A. D., Calkins, M. J., Jakel, R. J. and Johnson, J. A. (2005) Nrf2, a multi-organ protector? FASEB J. 19, 1061-1066.
-
(2005)
FASEB J
, vol.19
, pp. 1061-1066
-
-
Lee, J.M.1
Li, J.2
Johnson, D.A.3
Stein, T.D.4
Kraft, A.D.5
Calkins, M.J.6
Jakel, R.J.7
Johnson, J.A.8
-
13
-
-
19444379739
-
Nrf2 as a novel molecular target for chemoprevention
-
Lee, J. S. and Surh, Y. J. (2005) Nrf2 as a novel molecular target for chemoprevention. Cancer Lett. 224, 171-184.
-
(2005)
Cancer Lett
, vol.224
, pp. 171-184
-
-
Lee, J.S.1
Surh, Y.J.2
-
14
-
-
84892387002
-
Protective effect of arctigenin against MPP+ and MPTP-induced neurotoxicity
-
Li, D., Liu, Q., Jia, D., Dou, D., Wang, X. and Kang, T. (2014) Protective effect of arctigenin against MPP+ and MPTP-induced neurotoxicity. Planta Med. 80, 48-55.
-
(2014)
Planta Med
, vol.80
, pp. 48-55
-
-
Li, D.1
Liu, Q.2
Jia, D.3
Dou, D.4
Wang, X.5
Kang, T.6
-
15
-
-
33748310792
-
Peroxynitrite induces HO-1 expression via PI3K/Akt-dependent activation of NF-E2-related factor 2 in PC12 cells
-
Li, M. H., Cha Y. N. and Surh Y. J. (2006) Peroxynitrite induces HO-1 expression via PI3K/Akt-dependent activation of NF-E2-related factor 2 in PC12 cells. Free Radic. Biol. Med. 41, 1079-1091.
-
(2006)
Free Radic. Biol. Med
, vol.41
, pp. 1079-1091
-
-
Li, M.H.1
Cha, Y.N.2
Surh, Y.J.3
-
16
-
-
44549085003
-
Bromocriptine activates NQO1 via Nrf2-PI3K/Akt signaling: Novel cytoprotective mechanism against oxidative damage
-
Lim, J. H., Kim, K. M., Kim, S. W., Hwang, O. and Choi, H. J. (2008) Bromocriptine activates NQO1 via Nrf2-PI3K/Akt signaling: novel cytoprotective mechanism against oxidative damage. Pharmacol. Res. 57, 325-331.
-
(2008)
Pharmacol. Res
, vol.57
, pp. 325-331
-
-
Lim, J.H.1
Kim, K.M.2
Kim, S.W.3
Hwang, O.4
Choi, H.J.5
-
17
-
-
1542335553
-
Regulation of heme oxygenase-1 expression through the phosphatidylinositol 3-kinase/ Akt pathway and the Nrf2 transcription factor in response to the antioxidant phytochemical carnosol
-
Martin, D., Rojo, A. I., Salinas, M., Diaz, R., Gallardo, G., Alam, J., De, Galarreta, C.M. and Cuadrado, A. (2004) Regulation of heme oxygenase-1 expression through the phosphatidylinositol 3-kinase/ Akt pathway and the Nrf2 transcription factor in response to the antioxidant phytochemical carnosol. J. Biol. Chem. 279, 8919-8929.
-
(2004)
J. Biol. Chem
, vol.279
, pp. 8919-8929
-
-
Martin, D.1
Rojo, A.I.2
Salinas, M.3
Diaz, R.4
Gallardo, G.5
Alam, J.6
De Galarreta, C.M.7
Cuadrado, A.8
-
18
-
-
0034676493
-
Effects of antioxidant enzymes in the molecular control of reactive oxygen species toxicology
-
Mates, J. M. (2000) Effects of antioxidant enzymes in the molecular control of reactive oxygen species toxicology. Toxicology 153, 83- 104.
-
(2000)
Toxicology
, vol.153
, pp. 83-104
-
-
Mates, J.M.1
-
19
-
-
0043268709
-
Heme oxygenase-1: Unleashing the protective properties of heme
-
Otterbein, L. E., Soares, M. P., Yamashita, K. and Bach, F. H. (2003) Heme oxygenase-1: unleashing the protective properties of heme. Trends Immunol. 24, 449-455.
-
(2003)
Trends Immunol
, vol.24
, pp. 449-455
-
-
Otterbein, L.E.1
Soares, M.P.2
Yamashita, K.3
Bach, F.H.4
-
20
-
-
81255188816
-
Forsythiae fructus and its active component, arctigenin, provide neuroprotection by inhibiting neuroinflammation
-
Park, J. H., Hong, Y. J., Moon E., Kim S. A., and Kim, S. Y. (2011a) Forsythiae fructus and its active component, arctigenin, provide neuroprotection by inhibiting neuroinflammation. Biomol. Ther. 19, 425-430.
-
(2011)
Biomol. Ther
, vol.19
, pp. 425-430
-
-
Park, J.H.1
Hong, Y.J.2
Moon, E.3
Kim, S.A.4
Kim, S.Y.5
-
21
-
-
81255135965
-
Antioxidant mechanism of isoflavone metabolites in hydrogen peroxide-stimulated rat primary astrocytes: Critical role of hemeoxygenase-1 and NQO1 expression
-
Park, J. S., Jung, J. S., Jeong, Y. H., Hyun, J. W., Le, T. K., Kim, D. H., Choi, E. C. and Kim, H. S. (2011b) Antioxidant mechanism of isoflavone metabolites in hydrogen peroxide-stimulated rat primary astrocytes: critical role of hemeoxygenase-1 and NQO1 expression. J. Neurochem. 119, 909-919.
-
(2011)
J. Neurochem
, vol.119
, pp. 909-919
-
-
Park, J.S.1
Jung, J.S.2
Jeong, Y.H.3
Hyun, J.W.4
Le, T.K.5
Kim, D.H.6
Choi, E.C.7
Kim, H.S.8
-
22
-
-
84900461170
-
Regulation of hemeoxygenase-1 gene expression by Nrf2 and c-Jun in tertiary butylhydroquinonestimulated rat primary astrocytes
-
Park, J. S. and Kim, H. S. (2014) Regulation of hemeoxygenase-1 gene expression by Nrf2 and c-Jun in tertiary butylhydroquinonestimulated rat primary astrocytes. Biochem. Biophys. Res. Commun. 447, 672-677.
-
(2014)
Biochem. Biophys. Res. Commun
, vol.447
, pp. 672-677
-
-
Park, J.S.1
Kim, H.S.2
-
23
-
-
33847091290
-
Anti-inflammatory mechanisms of isoflavone metabolites in lipopolysaccharide-stimulated microglial cells
-
Park, J. S., Woo, M. S., Kim, D. H., Hyun, J. W., Kim, W. K., Lee, J. C. and Kim, H. S. (2007) Anti-inflammatory mechanisms of isoflavone metabolites in lipopolysaccharide-stimulated microglial cells. J. Pharmacol. Exp. Ther. 320, 1237-1245.
-
(2007)
J. Pharmacol. Exp. Ther
, vol.320
, pp. 1237-1245
-
-
Park, J.S.1
Woo, M.S.2
Kim, D.H.3
Hyun, J.W.4
Kim, W.K.5
Lee, J.C.6
Kim, H.S.7
-
24
-
-
33645945014
-
Heme oxygenase-1/ carbon monoxide: From basic science to therapeutic applications
-
Ryter, S. W., Alam, J. and Choi, A. M. (2006) Heme oxygenase-1/ carbon monoxide: from basic science to therapeutic applications. Physiol. Rev. 86, 583-650.
-
(2006)
Physiol. Rev
, vol.86
, pp. 583-650
-
-
Ryter, S.W.1
Alam, J.2
Choi, A.M.3
-
25
-
-
84912543798
-
-
Inflammation [Epub ahed of print]
-
Shi, X., Sun, H., Zhou, D., Xi, H. and Shan, L. (2014) Arctigenin attenuates lipopolysaccharide-induced acute lung injury in rats. Inflammation [Epub ahed of print]
-
(2014)
Arctigenin attenuates lipopolysaccharide-induced acute lung injury in rats
-
-
Shi, X.1
Sun, H.2
Zhou, D.3
Xi, H.4
Shan, L.5
-
26
-
-
0142166328
-
Cancer chemoprevention with dietary phytochemicals
-
Surh Y. J. (2003) Cancer chemoprevention with dietary phytochemicals. Nat. Rev. Cancer 3, 768-780.
-
(2003)
Nat. Rev. Cancer
, vol.3
, pp. 768-780
-
-
Surh, Y.J.1
-
27
-
-
54949143147
-
Regulation of haeme oxygenase-1 for treatment of neuroinflammation and brain disorders
-
Syapin, P. J. (2008) Regulation of haeme oxygenase-1 for treatment of neuroinflammation and brain disorders. Br. J. Pharmacol. 155, 623-640.
-
(2008)
Br. J. Pharmacol
, vol.155
, pp. 623-640
-
-
Syapin, P.J.1
-
28
-
-
70349333698
-
The Nrf2-ARE cytoprotective pathway in astrocytes
-
Vargas, M. R. and Johnson, J. A. (2009) The Nrf2-ARE cytoprotective pathway in astrocytes. Expert Rev. Mol. Med. 11, e17.
-
(2009)
Expert Rev. Mol. Med
, vol.11
-
-
Vargas, M.R.1
Johnson, J.A.2
-
29
-
-
84861455914
-
Upregulation of heme oxygenase-1 by acteoside through ERK and PI3 K/Akt pathway confer neuroprotection against beta-amyloid-induced neurotoxicity
-
Wang, H. Q., Xu, Y. X. and Zhu, C. Q. (2012) Upregulation of heme oxygenase-1 by acteoside through ERK and PI3 K/Akt pathway confer neuroprotection against beta-amyloid-induced neurotoxicity. Neurotox. Res. 21, 368-378.
-
(2012)
Neurotox. Res
, vol.21
, pp. 368-378
-
-
Wang, H.Q.1
Xu, Y.X.2
Zhu, C.Q.3
-
30
-
-
0038243778
-
Selective modulation of lipopolysaccharide-stimulated cytokine expression and mitogen-activated protein kinase pathways by dibutyryl-cAMP in BV2 microglial cells
-
Woo, M. S., Jang, P. G., Park, J. S., Kim, W. K., Joh, T. H. and Kim, H. S. (2003) Selective modulation of lipopolysaccharide-stimulated cytokine expression and mitogen-activated protein kinase pathways by dibutyryl-cAMP in BV2 microglial cells. Brain Res. Mol. Brain Res. 113, 86-96.
-
(2003)
Brain Res. Mol. Brain Res
, vol.113
, pp. 86-96
-
-
Woo, M.S.1
Jang, P.G.2
Park, J.S.3
Kim, W.K.4
Joh, T.H.5
Kim, H.S.6
-
31
-
-
84912534519
-
Arctigenin enhances swimming endurance of sedentary rats partially by regulation of antioxidant pathways
-
Wu, R. M., Sun, Y. Y., Zhou, T. T., Zhu, Z. Y., Zhuang, J. J., Tang, X., Chen, J., Hu, L. H. and Shen, X. (2014) Arctigenin enhances swimming endurance of sedentary rats partially by regulation of antioxidant pathways. Acta Pharmacol. Sin. 35, 1274-1284.
-
(2014)
Acta Pharmacol. Sin
, vol.35
, pp. 1274-1284
-
-
Wu, R.M.1
Sun, Y.Y.2
Zhou, T.T.3
Zhu, Z.Y.4
Zhuang, J.J.5
Tang, X.6
Chen, J.7
Hu, L.H.8
Shen, X.9
-
32
-
-
84881173817
-
Arctigenin effectively ameliorates memory impairment in Alzheimer's disease model mice targeting both beta-amyloid production and clearance
-
Zhu, Z., Yan, J., Jiang, W., Yao, X. G., Chen, J., Chen, L., Li, C., Hu, L., Jiang, H. and Shen, X. (2013) Arctigenin effectively ameliorates memory impairment in Alzheimer's disease model mice targeting both beta-amyloid production and clearance. J. Neurosci. 33, 13138-13149.
-
(2013)
J. Neurosci
, vol.33
, pp. 13138-13149
-
-
Zhu, Z.1
Yan, J.2
Jiang, W.3
Yao, X.G.4
Chen, J.5
Chen, L.6
Li, C.7
Hu, L.8
Jiang, H.9
Shen, X.10
|