Anti-inflammatory mechanism of ginsenoside Rh1 in lipopolysaccharide- stimulated microglia: Critical role of the protein kinase A pathway and hemeoxygenase-1 expression

Journal of Neurochemistry

Volumn 115, Issue 6, 2010, Pages 1668-1680

  Jung, Ji Sun ^a   Shin, Jin A ^a   Park, Eun Mi ^a   Lee, Jung Eun ^b   Kang, Young Sook ^b   Min, Sung Won ^c   Kim, Dong Hyun ^c   Hyun, Jin Won ^d   Shin, Chan Young ^e   Kim, Hee Sun ^a  

^a Ewha Womans University School of Medicine   (South Korea)

^b Sookmyung Women's University   (South Korea)

^c Kyung Hee University   (South Korea)

^d Jeju National University School of Medicine   (South Korea)

^e Konkuk University School of Medicine   (South Korea)

Author keywords

CREB; ginsenoside Rh1; HO 1; neuroinflammation; PKA

Indexed keywords

CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; CYCLOOXYGENASE 2; GINSENOSIDE; GINSENOSIDE RH 1; HEME OXYGENASE 1; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; MITOGEN ACTIVATED PROTEIN KINASE; SHORT HAIRPIN RNA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; BINDING AFFINITY; BRAIN REGION; CELL ACTIVATION; CONTROLLED STUDY; DRUG EFFICACY; DRUG STRUCTURE; IMMUNOREACTIVITY; MALE; MICROGLIA; MOUSE; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DNA BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; RAT; UPREGULATION;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CELL LINE, TRANSFORMED; CELL LINE, TUMOR; CELLS, CULTURED; COCULTURE TECHNIQUES; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GINSENOSIDES; HEME OXYGENASE-1; LIPOPOLYSACCHARIDES; MALE; MICE; MICE, INBRED C57BL; MICROGLIA; PANAX; RANDOM ALLOCATION; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION;

EID: 78649993974     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2010.07075.x     Document Type: Article

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