Tissue localization of nanoparticles is altered due to hypoxia resulting in poor efficacy of curcumin nanoparticles in pulmonary hypertension

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 80, Issue 3, 2012, Pages 578-584

  Devadasu, Venkat Ratnam ^a   Wadsworth, Roger M ^a   Ravi Kumar, M N V ^a  

^a UNIVERSITY OF STRATHCLYDE   (United Kingdom)

Author keywords

Chronic hypoxia; Curcumin; Oral delivery; Polymeric nanoparticles; Pulmonary hypertension; Tissue distribution

Indexed keywords

CURCUMIN; NANOPARTICLE; POLYGLACTIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD FLOW; DRUG DISTRIBUTION; DRUG TREATMENT FAILURE; ENDOCYTOSIS; HEART RIGHT VENTRICLE HYPERTROPHY; HEMATOCRIT; HYPOXIA; LUNG BLOOD VESSEL; MALE; NANOENCAPSULATION; NONHUMAN; PULMONARY HYPERTENSION; RAT; TISSUE DISTRIBUTION;

ADMINISTRATION, ORAL; ANIMALS; ANOXIA; CURCUMIN; HYPERTENSION, PULMONARY; HYPERTROPHY, RIGHT VENTRICULAR; LACTIC ACID; LUNG; MALE; NANOPARTICLES; POLYGLYCOLIC ACID; PULMONARY ARTERY; RATS; RATS, SPRAGUE-DAWLEY; TISSUE DISTRIBUTION;

EID: 84858153071     PISSN: 09396411     EISSN: 18733441     Source Type: Journal    
DOI: 10.1016/j.ejpb.2011.12.008     Document Type: Article

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