Stabilization and sustained release of zeylenone, a soft cytotoxic drug, within polymeric micelles for local antitumor drug delivery

International Journal of Pharmaceutics

Volumn 450, Issue 1-2, 2013, Pages 331-337

  Hu, Xiao ^a   Han, Rong ^a   Quan, Li Hui ^a   Liu, Chun Yu ^a   Liao, Yong Hong ^a  

^a INSTITUTE OF MEDICINAL PLANT DEVELOPMENT   (China)

Author keywords

Antitumor; mPEG PLGA; Polymeric micelles; Soft drugs; Zeylenone

Indexed keywords

CYTOTOXIC AGENT; MACROGOL; UNCLASSIFIED DRUG; ZEYLENONE;

ANIMAL EXPERIMENT; ANIMAL MODEL; AQUEOUS SOLUTION; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG EFFICACY; DRUG HALF LIFE; DRUG STABILITY; ENCAPSULATION; EVAPORATION; IN VITRO STUDY; IN VIVO STUDY; MALE; MICELLE; MOUSE; NONHUMAN; PARTICLE SIZE; POLYMERIC MICELLE; PRIORITY JOURNAL; SUSTAINED DRUG RELEASE; ZETA POTENTIAL;

ANIMALS; CELL LINE, TUMOR; CYCLOHEXANES; CYTOTOXINS; DELAYED-ACTION PREPARATIONS; DIOXANES; DRUG CARRIERS; DRUG STABILITY; HUMANS; MALE; MICELLES; NEOPLASMS; POLYESTERS; POLYETHYLENE GLYCOLS; RATS; RATS, WISTAR; TUMOR BURDEN; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84878351046     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2013.04.007     Document Type: Article

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