Skin barrier disruptions in tape stripped and allergic dermatitis models have no effect on dermal penetration and systemic distribution of AHAPS-functionalized silica nanoparticles

Nanomedicine: Nanotechnology, Biology, and Medicine

Volumn 10, Issue 7, 2014, Pages 1571-1581

  Ostrowski, Anja ^a   Nordmeyer, Daniel ^a   Boreham, Alexander ^a   Brodwolf, Robert ^a,b   Mundhenk, Lars ^a   Fluhr, Joachim W ^c   Lademann, Jürgen ^c   Graf, Christina ^a   Rühl, Eckart ^a   Alexiev, Ulrike ^a,b   Gruber, Achim D ^a  

^a FREIE UNIVERSITÄT BERLIN   (Germany)

^b INSTITUTE OF MATERIALS RESEARCH   (Germany)

^c CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

Allergic contact dermatitis; FLIM; Fluorescence microscopy; Murine model; Tape stripping

Indexed keywords

FLUORESCENCE MICROSCOPY; MAMMALS; MEDICAL APPLICATIONS; NANOPARTICLES; SILICA; SILICON; SIO2 NANOPARTICLES;

ALLERGIC CONTACT DERMATITIS; AMINOPROPYLTRIMETHOXYSILANE; DERMAL PENETRATION; FLIM; FUNCTIONALIZED SILICA; MURINE MODEL; SKIN PENETRATION; TAPE STRIPPING;

SILICA NANOPARTICLES;

ADHESIVE AGENT; N (6 AMINOHEXYL)AMINOPROPYLTRIMETHOXYSILANE FUNCTIONALIZED SILICA NANOPARTICLE; NANOPARTICLE; SILANE DERIVATIVE; SILICA NANOPARTICLE; SILICON DIOXIDE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG DISTRIBUTION; DRUG PENETRATION; DRUG TRANSPORT; HISTOPATHOLOGY; LYMPH NODE; MACROPHAGE; MALE; MOUSE; NONHUMAN; PARTICLE SIZE; PERMEABILITY BARRIER; SKIN ALLERGY; SKIN PENETRATION; SKIN PERMEABILITY; ANIMAL; CONTACT DERMATITIS; DISEASE MODEL; PATHOPHYSIOLOGY; SKIN; SKIN ABSORPTION; TRANSMISSION ELECTRON MICROSCOPY;

MURINAE;

ANIMALS; DERMATITIS, CONTACT; DISEASE MODELS, ANIMAL; MALE; MICE; MICROSCOPY, ELECTRON, TRANSMISSION; NANOPARTICLES; SILICON DIOXIDE; SKIN; SKIN ABSORPTION;

EID: 84912150731     PISSN: 15499634     EISSN: 15499642     Source Type: Journal    
DOI: 10.1016/j.nano.2014.04.004     Document Type: Article

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