Toxicity of amorphous silica nanoparticles in mouse keratinocytes

Journal of Nanoparticle Research

Volumn 11, Issue 1, 2009, Pages 15-24

  Yu, Kyung O ^a   Grabinski, Christin M ^a   Schrand, Amanda M ^a   Murdock, Richard C ^a   Wang, Wei ^b   Gu, Baohua ^b   Schlager, John J ^a   Hussain, Saber M ^a  

^a AIR FORCE RESEARCH LABORATORY   (United States)

^b OAK RIDGE NATIONAL LABORATORY   (United States)

Author keywords

EHS; Mouse keratinocytes; Nanotechnology; Occupational health; Oxidative stress; Size dependent toxicity of nanoparticles

Indexed keywords

AMORPHOUS SILICAS; BIOCHEMICAL CHANGES; BIOLOGICAL EFFECTS; CYTOTOXIC EFFECTS; EHS; HIGH CONCENTRATIONS; HOMOGENEOUS SUSPENSIONS; LACTATE DEHYDROGENASES; MEMBRANE POTENTIALS; MOUSE KERATINOCYTES; OCCUPATIONAL HEALTH; REACTIVE OXYGEN SPECIES; REDOX POTENTIALS; SILICA NANOPARTICLES; SIZE-DEPENDENT TOXICITY OF NANOPARTICLES;

CELL MEMBRANES; CYTOLOGY; INDUSTRIAL HYGIENE; NANOTECHNOLOGY; OCCUPATIONAL RISKS; OXIDES; OXYGEN; SILICA; SILICON COMPOUNDS; TOXICITY;

NANOPARTICLES;

GLUTATHIONE; LACTATE DEHYDROGENASE; NANOPARTICLE; SILICON DIOXIDE;

ANIMAL CELL; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; CYTOPLASM; CYTOTOXICITY; KERATINOCYTE; MITOCHONDRION; MOUSE; NONHUMAN; PRIORITY JOURNAL; TRANSMISSION ELECTRON MICROSCOPY;

EID: 58149184044     PISSN: 13880764     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11051-008-9417-9     Document Type: Article

References (25)

1. SC Brown M Kamal N Nasreen A Baumuratov P Sharma V Anthony BM Moudgil 2007 Influence of shape, adhesion and simulated lung mechanics on amorphous silica nanoparticle toxicity Adv Powder Technol 18 69 79
2. ZS Csogör M Nacken M Sameti C-M Lehr H Schmidt 2003 Modified silica particles for gene delivery Mater Sci Eng C 23 93 97
3. K Donaldson V Stone CL Tran W Kreyling PJA Borm 2004 Nanotoxicology Occup Environ Med 61 727 728
4. R Hardman 2006 A toxicologic review of quantum dots: toxicity depends on physicochemical and environmental factors Environ Health Perspect 114 165 172
5. PHM Hoet I Brueske-Hohlfeld O Salata 2004 Nanoparticles-known and unknown health risks J Nanotoxicol 2 1 2
6. A Jillavenkatesa JF Kelly 2002 Nanopowder characterization: challenges and future directions J Nanopart Res 4 463 468
7. J Lademann H Weigmann C Rickmeyer H Barthelmes H Schaefer G Mueller W Sterry 1999 Penetration of titanium dioxide microparticles in a sunscreen formulation into the horny layer and the follicular orifice Skin Pharmacol Appl Skin Physiol 12 247 256
8. C-W Lam JT James R McClustkey R Hunter 2004 Pulmonary toxicity of single-wall carbon nanotubes in mice 7 and 90 days after intratracheal instillation Toxicol Sci 77 126 134
9. W Lin Y-W Huang X-D Zhou Y Ma 2006 In vitro toxicity of silica nanoparticles in human lung cancer cells Toxicol Appl Pharmacol 217 252 259
10. MJ McCabe Jr 2003 Mechanisms and consequences of silica-induced apoptosis Toxicol Sci 76 1 2
11. RC Murdock L Braydich-Stolle AM Schrand JL Schlager SM Hussain 2008 Characterization of nanomaterial dispersion in solution prior to in vitro exposure via dynamic light scattering Toxicol Sci 101 239 253
12. A Nel T Xia L Maedler N Li 2006 Toxic potential of materials at the nanolevel Science 311 622 626
13. G Oberdoerster E Oberdoerster J Oberdoerster 2005 Nanotoxicology: an emerging discipline evolving from studies of ultrafine particles Environ Health Perspect 113 823 839
14. KW Powers SC Brown VB Krishna SC Wasdo BM Modgil SM Roberts 2006 Research strategies for safety evaluation of nanomaterials. Part VI. Characterization of nanoscale particles for toxicological evaluation Toxicol Sci 90 296 303
15. I Roy T Ohulchanskyy D Bharali H Pudavar R Mistretta N Kaur P Prasad 2005 Optical tracking of organically modified silica nanoparticles as DNA carriers: a nonviral, nanomedicine approach for gene delivery PNAS 102 279 284
16. JP Ryman-Rrasnyssen JE Riviere NA Monteiro-Riviere 2006 Penetration of intact skin by quantum dots with diverse physicochemical properties Toxicol Sci 91 159 165
17. R Service 2005 Calls rise for more research on toxicology of nanomaterials Science 310 1609
18. M Thibodeau C Giardina DA Knecht J Helble AK Hubbare 2004 Silica-induced apoptosis in mouse alveolar macrophages is initiated by lysosomal enzyme activity Toxicol Sci 80 34 48
19. MP Vinardell 2005 In vitro cytotoxicity of nanoparticles in mammalian germ-line stem cell Toxicol Sci 88 285 286
20. AA Vertegel RW Aiegel JS Dordick 2004 Silica nanoparticle size influences the structure and enzyme activity of adsorbed lysozyme Langmuir 20 6800 6807
21. H Wang JA Joseph 1999 Quantitating cellular oxidative stress by dichlorofluorescein assay using microplate reader Free Radic Biol Med 27 612 616
22. W Wang B Gu L Liang W Hamilton 2003 Fabrication of two- and three-dimensional silica nanocolloidal particle arrays J Phys Chem B 107 3400 3404
23. 2 spheres J Phys Chem B 107 12113 12117
24. DB Warheit BR Laurence KL Reed DH Roach GAM Reynolds TR Weff 2004 Comparative pulmonary toxicity assessment of single-wall carbon nanotubes in rats Toxicol Sci 77 117 125
25. Y Zhou R Yokel 2005 The chemical species of aluminum influence its paracellular flux and uptake into Caco-2 cells, a model of gastrointestinal absorption Toxicol Sci 87 15 26