메뉴 건너뛰기




Volumn 10, Issue 11, 2014, Pages

The Red Queen Model of Recombination Hotspots Evolution in the Light of Archaic and Modern Human Genomes

Author keywords

[No Author keywords available]

Indexed keywords

PRDM9 PROTEIN; UNCLASSIFIED DRUG; ZINC FINGER PROTEIN; DNA BINDING PROTEIN; HISTONE LYSINE METHYLTRANSFERASE; PRDM9 PROTEIN, HUMAN;

EID: 84912075548     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1004790     Document Type: Article
Times cited : (53)

References (52)
  • 1
    • 33845746387 scopus 로고    scopus 로고
    • An evolutionary view of human recombination
    • Coop G, Przeworski M, (2007) An evolutionary view of human recombination. Nat Rev Genet 8: 23–34 doi:10.1038/nrg1947
    • (2007) Nat Rev Genet , vol.8 , pp. 23-34
    • Coop, G.1    Przeworski, M.2
  • 2
    • 35348983887 scopus 로고    scopus 로고
    • A second generation human haplotype map of over 3.1 million SNPs
    • The International HapMap Consortium (2007) A second generation human haplotype map of over 3.1 million SNPs. Nature 449: 851–861 doi:10.1038/nature06258
    • (2007) Nature , vol.449 , pp. 851-861
  • 3
    • 26844482093 scopus 로고    scopus 로고
    • A fine-scale map of recombination rates and hotspots across the human genome
    • Myers S, Bottolo L, Freeman C, McVean G, Donnelly P, (2005) A fine-scale map of recombination rates and hotspots across the human genome. Science 310: 321–324 doi:10.1126/science.1117196
    • (2005) Science , vol.310 , pp. 321-324
    • Myers, S.1    Bottolo, L.2    Freeman, C.3    McVean, G.4    Donnelly, P.5
  • 4
    • 79955480674 scopus 로고    scopus 로고
    • Genome-wide analysis reveals novel molecular features of mouse recombination hotspots
    • Smagulova F, Gregoretti I V, Brick K, Khil P, Camerini-Otero RD, et al. (2011) Genome-wide analysis reveals novel molecular features of mouse recombination hotspots. Nature 472: 375–378 doi:10.1038/nature09869
    • (2011) Nature , vol.472 , pp. 375-378
    • Smagulova, F.1    Gregoretti I, V.2    Brick, K.3    Khil, P.4    Camerini-Otero, R.D.5
  • 5
    • 84855332221 scopus 로고    scopus 로고
    • Death of PRDM9 coincides with stabilization of the recombination landscape in the dog genome
    • Axelsson E, Webster MT, Ratnakumar A, Ponting CP, Lindblad-Toh K, (2012) Death of PRDM9 coincides with stabilization of the recombination landscape in the dog genome. Genome Res 22: 51–63 doi:10.1101/gr.124123.111
    • (2012) Genome Res , vol.22 , pp. 51-63
    • Axelsson, E.1    Webster, M.T.2    Ratnakumar, A.3    Ponting, C.P.4    Lindblad-Toh, K.5
  • 6
    • 84892721054 scopus 로고    scopus 로고
    • Genetic Recombination Is Targeted towards Gene Promoter Regions in Dogs
    • Auton A, Rui Li Y, Kidd J, Oliveira K, Nadel J, et al. (2013) Genetic Recombination Is Targeted towards Gene Promoter Regions in Dogs. PLoS Genet 9: e1003984 doi:10.1371/journal.pgen.1003984
    • (2013) PLoS Genet , vol.9 , pp. e1003984
    • Auton, A.1    Rui Li, Y.2    Kidd, J.3    Oliveira, K.4    Nadel, J.5
  • 7
    • 84887106752 scopus 로고    scopus 로고
    • Arabidopsis meiotic crossover hot spots overlap with H2A.Z nucleosomes at gene promoters
    • Choi K, Zhao X, Kelly KA, Venn O, Higgins JD, et al. (2013) Arabidopsis meiotic crossover hot spots overlap with H2A.Z nucleosomes at gene promoters. Nat Genet 45: 1327–1336 doi:10.1038/ng.2766
    • (2013) Nat Genet , vol.45 , pp. 1327-1336
    • Choi, K.1    Zhao, X.2    Kelly, K.A.3    Venn, O.4    Higgins, J.D.5
  • 8
    • 79952295560 scopus 로고    scopus 로고
    • A hierarchical combination of factors shapes the genome-wide topography of yeast meiotic recombination initiation
    • Pan J, Sasaki M, Kniewel R, Murakami H, Blitzblau HG, et al. (2011) A hierarchical combination of factors shapes the genome-wide topography of yeast meiotic recombination initiation. Cell 144: 719–731 doi:10.1016/j.cell.2011.02.009
    • (2011) Cell , vol.144 , pp. 719-731
    • Pan, J.1    Sasaki, M.2    Kniewel, R.3    Murakami, H.4    Blitzblau, H.G.5
  • 9
    • 76749170346 scopus 로고    scopus 로고
    • PRDM9 is a major determinant of meiotic recombination hotspots in humans and mice
    • Baudat F, Buard J, Grey C, Fledel-Alon A, Ober C, et al. (2010) PRDM9 is a major determinant of meiotic recombination hotspots in humans and mice. Science 327: 836–840 doi:10.1126/science.1183439
    • (2010) Science , vol.327 , pp. 836-840
    • Baudat, F.1    Buard, J.2    Grey, C.3    Fledel-Alon, A.4    Ober, C.5
  • 10
    • 76749155072 scopus 로고    scopus 로고
    • Drive against hotspot motifs in primates implicates the PRDM9 gene in meiotic recombination
    • Myers S, Bowden R, Tumian A, Bontrop RE, Freeman C, et al. (2010) Drive against hotspot motifs in primates implicates the PRDM9 gene in meiotic recombination. Science 327: 876–879 doi:10.1126/science.1182363
    • (2010) Science , vol.327 , pp. 876-879
    • Myers, S.1    Bowden, R.2    Tumian, A.3    Bontrop, R.E.4    Freeman, C.5
  • 11
    • 77957579303 scopus 로고    scopus 로고
    • PRDM9 variation strongly influences recombination hot-spot activity and meiotic instability in humans
    • Berg IL, Neumann R, Lam K-WG, Sarbajna S, Odenthal-Hesse L, et al. (2010) PRDM9 variation strongly influences recombination hot-spot activity and meiotic instability in humans. Nat Genet 42: 859–863 doi:10.1038/ng.658
    • (2010) Nat Genet , vol.42 , pp. 859-863
    • Berg, I.L.1    Neumann, R.2    Lam, K.-W.G.3    Sarbajna, S.4    Odenthal-Hesse, L.5
  • 12
    • 84863770992 scopus 로고    scopus 로고
    • Genetic recombination is directed away from functional genomic elements in mice
    • Brick K, Smagulova F, Khil P, Camerini-Otero RD, Petukhova G V, (2012) Genetic recombination is directed away from functional genomic elements in mice. Nature 485: 642–645 doi:10.1038/nature11089
    • (2012) Nature , vol.485 , pp. 642-645
    • Brick, K.1    Smagulova, F.2    Khil, P.3    Camerini-Otero, R.D.4    Petukhova G, V.5
  • 13
    • 27844440989 scopus 로고    scopus 로고
    • A histone H3 methyltransferase controls epigenetic events required for meiotic prophase
    • Hayashi K, Yoshida K, Matsui Y, (2005) A histone H3 methyltransferase controls epigenetic events required for meiotic prophase. Nature 438: 374–378 doi:10.1038/nature04112
    • (2005) Nature , vol.438 , pp. 374-378
    • Hayashi, K.1    Yoshida, K.2    Matsui, Y.3
  • 14
    • 80055056367 scopus 로고    scopus 로고
    • Mouse PRDM9 DNA-binding specificity determines sites of histone H3 lysine 4 trimethylation for initiation of meiotic recombination
    • Grey C, Barthès P, Chauveau-Le Friec G, Langa F, Baudat F, et al. (2011) Mouse PRDM9 DNA-binding specificity determines sites of histone H3 lysine 4 trimethylation for initiation of meiotic recombination. PLoS Biol 9: e1001176 doi:10.1371/journal.pbio.1001176
    • (2011) PLoS Biol , vol.9 , pp. e1001176
    • Grey, C.1    Barthès, P.2    Chauveau-Le Friec, G.3    Langa, F.4    Baudat, F.5
  • 15
    • 79961097286 scopus 로고    scopus 로고
    • Variants of the protein PRDM9 differentially regulate a set of human meiotic recombination hotspots highly active in African populations
    • Berg IL, Neumann R, Sarbajna S, Odenthal-Hesse L, Butler NJ, et al. (2011) Variants of the protein PRDM9 differentially regulate a set of human meiotic recombination hotspots highly active in African populations. Proc Natl Acad Sci U S A 108: 12378–12383 doi:10.1073/pnas.1109531108
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 12378-12383
    • Berg, I.L.1    Neumann, R.2    Sarbajna, S.3    Odenthal-Hesse, L.4    Butler, N.J.5
  • 16
    • 80051679387 scopus 로고    scopus 로고
    • The landscape of recombination in African Americans
    • Hinch AG, Tandon A, Patterson N, Song Y, Rohland N, et al. (2011) The landscape of recombination in African Americans. Nature 476: 170–175 doi:10.1038/nature10336
    • (2011) Nature , vol.476 , pp. 170-175
    • Hinch, A.G.1    Tandon, A.2    Patterson, N.3    Song, Y.4    Rohland, N.5
  • 17
    • 50449088155 scopus 로고    scopus 로고
    • A common sequence motif associated with recombination hot spots and genome instability in humans
    • Myers S, Freeman C, Auton A, Donnelly P, McVean G, (2008) A common sequence motif associated with recombination hot spots and genome instability in humans. Nat Genet 40: 1124–1129 doi:10.1038/ng.213
    • (2008) Nat Genet , vol.40 , pp. 1124-1129
    • Myers, S.1    Freeman, C.2    Auton, A.3    Donnelly, P.4    McVean, G.5
  • 18
    • 16844377748 scopus 로고    scopus 로고
    • Fine-scale recombination patterns differ between chimpanzees and humans
    • Ptak SE, Hinds DA, Koehler K, Nickel B, Patil N, et al. (2005) Fine-scale recombination patterns differ between chimpanzees and humans. Nat Genet 37: 429–434 doi:10.1038/ng1529
    • (2005) Nat Genet , vol.37 , pp. 429-434
    • Ptak, S.E.1    Hinds, D.A.2    Koehler, K.3    Nickel, B.4    Patil, N.5
  • 19
    • 84859636918 scopus 로고    scopus 로고
    • A fine-scale chimpanzee genetic map from population sequencing
    • Auton A, Fledel-Alon A, Pfeifer S, Venn O, Ségurel L, et al. (2012) A fine-scale chimpanzee genetic map from population sequencing. Science 336: 193–198 doi:10.1126/science.1216872
    • (2012) Science , vol.336 , pp. 193-198
    • Auton, A.1    Fledel-Alon, A.2    Pfeifer, S.3    Venn, O.4    Ségurel, L.5
  • 20
    • 20144387806 scopus 로고    scopus 로고
    • Comparison of fine-scale recombination rates in humans and chimpanzees
    • Winckler W, Myers SR, Richter DJ, Onofrio RC, McDonald GJ, et al. (2005) Comparison of fine-scale recombination rates in humans and chimpanzees. Science 308: 107–111 doi:10.1126/science.1105322
    • (2005) Science , vol.308 , pp. 107-111
    • Winckler, W.1    Myers, S.R.2    Richter, D.J.3    Onofrio, R.C.4    McDonald, G.J.5
  • 21
    • 74249088732 scopus 로고    scopus 로고
    • Accelerated evolution of the Prdm9 speciation gene across diverse metazoan taxa
    • Oliver PL, Goodstadt L, Bayes JJ, Birtle Z, Roach KC, et al. (2009) Accelerated evolution of the Prdm9 speciation gene across diverse metazoan taxa. PLoS Genet 5: e1000753 doi:10.1371/journal.pgen.1000753
    • (2009) PLoS Genet , vol.5 , pp. e1000753
    • Oliver, P.L.1    Goodstadt, L.2    Bayes, J.J.3    Birtle, Z.4    Roach, K.C.5
  • 22
    • 79955095683 scopus 로고    scopus 로고
    • What are the genomic drivers of the rapid evolution of PRDM9?
    • Ponting CP, (2011) What are the genomic drivers of the rapid evolution of PRDM9? Trends Genet 27: 165–171 doi:10.1016/j.tig.2011.02.001
    • (2011) Trends Genet , vol.27 , pp. 165-171
    • Ponting, C.P.1
  • 23
    • 0030791317 scopus 로고    scopus 로고
    • The hotspot conversion paradox and the evolution of meiotic recombination
    • Boulton A, Myers RS, Redfield RJ, (1997) The hotspot conversion paradox and the evolution of meiotic recombination. Proc Natl Acad Sci U S A 94: 8058–8063.
    • (1997) Proc Natl Acad Sci U S A , vol.94 , pp. 8058-8063
    • Boulton, A.1    Myers, R.S.2    Redfield, R.J.3
  • 24
    • 0036649022 scopus 로고    scopus 로고
    • Reciprocal crossover asymmetry and meiotic drive in a human recombination hot spot
    • Jeffreys AJ, Neumann R, (2002) Reciprocal crossover asymmetry and meiotic drive in a human recombination hot spot. Nat Genet 31: 267–271 doi:10.1038/ng910
    • (2002) Nat Genet , vol.31 , pp. 267-271
    • Jeffreys, A.J.1    Neumann, R.2
  • 25
    • 34047200066 scopus 로고    scopus 로고
    • Live hot, die young: transmission distortion in recombination hotspots
    • Coop G, Myers SR, (2007) Live hot, die young: transmission distortion in recombination hotspots. PLoS Genet 3: e35 doi:10.1371/journal.pgen.0030035
    • (2007) PLoS Genet , vol.3 , pp. e35
    • Coop, G.1    Myers, S.R.2
  • 27
    • 79951755719 scopus 로고    scopus 로고
    • The Red Queen theory of recombination hotspots
    • Ubeda F, Wilkins JF, (2011) The Red Queen theory of recombination hotspots. J Evol Biol 24: 541–553 doi:10.1111/j.1420-9101.2010.02187.x
    • (2011) J Evol Biol , vol.24 , pp. 541-553
    • Ubeda, F.1    Wilkins, J.F.2
  • 28
    • 84867331947 scopus 로고    scopus 로고
    • A high-coverage genome sequence from an archaic Denisovan individual
    • Meyer M, Kircher M, Gansauge M-T, Li H, Racimo F, et al. (2012) A high-coverage genome sequence from an archaic Denisovan individual. Science 338: 222–226 doi:10.1126/science.1224344
    • (2012) Science , vol.338 , pp. 222-226
    • Meyer, M.1    Kircher, M.2    Gansauge, M.-T.3    Li, H.4    Racimo, F.5
  • 29
    • 84866856766 scopus 로고    scopus 로고
    • Generation times in wild chimpanzees and gorillas suggest earlier divergence times in great ape and human evolution
    • Langergraber KE, Prüfer K, Rowney C, Boesch C, Crockford C, et al. (2012) Generation times in wild chimpanzees and gorillas suggest earlier divergence times in great ape and human evolution. Proc Natl Acad Sci U S A 109: 15716–15721 doi:10.1073/pnas.1211740109
    • (2012) Proc Natl Acad Sci U S A , vol.109 , pp. 15716-15721
    • Langergraber, K.E.1    Prüfer, K.2    Rowney, C.3    Boesch, C.4    Crockford, C.5
  • 30
    • 84975742565 scopus 로고    scopus 로고
    • A map of human genome variation from population-scale sequencing
    • The 1000 Genomes Project Consortium (2010) A map of human genome variation from population-scale sequencing. Nature 467: 1061–1073 doi:10.1038/nature09534
    • (2010) Nature , vol.467 , pp. 1061-1073
  • 31
    • 84975795680 scopus 로고    scopus 로고
    • An integrated map of genetic variation from 1,092 human genomes
    • The 1000 Genomes Project Consortium (2012) An integrated map of genetic variation from 1,092 human genomes. Nature 491: 56–65 doi:10.1038/nature11632
    • (2012) Nature , vol.491 , pp. 56-65
  • 32
    • 0021077332 scopus 로고
    • Evolution of a finite population under gene conversion
    • Nagylaki T, (1983) Evolution of a finite population under gene conversion. Proc Natl Acad Sci U S A 80: 6278–6281.
    • (1983) Proc Natl Acad Sci U S A , vol.80 , pp. 6278-6281
    • Nagylaki, T.1
  • 33
    • 84867331947 scopus 로고    scopus 로고
    • Meyer M, Kircher M, Gansauge M-T, Li H, Racimo F, et al. (2012) A High-Coverage Genome Sequence from an Archaic Denisovan Individual. Science (80-) in press: 1–10. doi:10.1126/science.1224344.
  • 34
    • 33745347447 scopus 로고    scopus 로고
    • The distribution of fitness effects of new deleterious amino acid mutations in humans
    • Eyre-Walker A, Woolfit M, Phelps T, (2006) The distribution of fitness effects of new deleterious amino acid mutations in humans. Genetics 173: 891–900 doi:10.1534/genetics.106.057570
    • (2006) Genetics , vol.173 , pp. 891-900
    • Eyre-Walker, A.1    Woolfit, M.2    Phelps, T.3
  • 35
    • 78049354879 scopus 로고    scopus 로고
    • Fine-scale recombination rate differences between sexes, populations and individuals
    • Kong A, Thorleifsson G, Gudbjartsson DF, Masson G, Sigurdsson A, et al. (2010) Fine-scale recombination rate differences between sexes, populations and individuals. Nature 467: 1099–1103 doi:10.1038/nature09525
    • (2010) Nature , vol.467 , pp. 1099-1103
    • Kong, A.1    Thorleifsson, G.2    Gudbjartsson, D.F.3    Masson, G.4    Sigurdsson, A.5
  • 36
    • 70350236484 scopus 로고    scopus 로고
    • Biased gene conversion and the evolution of mammalian genomic landscapes
    • Duret L, Galtier N, (2009) Biased gene conversion and the evolution of mammalian genomic landscapes. Annu Rev Genomics Hum Genet 10: 285–311 doi:10.1146/annurev-genom-082908-150001
    • (2009) Annu Rev Genomics Hum Genet , vol.10 , pp. 285-311
    • Duret, L.1    Galtier, N.2
  • 37
    • 84877771672 scopus 로고    scopus 로고
    • GC-biased gene conversion in yeast is specifically associated with crossovers: molecular mechanisms and evolutionary significance
    • Lesecque Y, Mouchiroud D, Duret L, (2013) GC-biased gene conversion in yeast is specifically associated with crossovers: molecular mechanisms and evolutionary significance. Mol Biol Evol 30: 1409–1419 doi:10.1093/molbev/mst056
    • (2013) Mol Biol Evol , vol.30 , pp. 1409-1419
    • Lesecque, Y.1    Mouchiroud, D.2    Duret, L.3
  • 38
    • 44949198268 scopus 로고    scopus 로고
    • The impact of recombination on nucleotide substitutions in the human genome
    • Duret L, Arndt PF, (2008) The impact of recombination on nucleotide substitutions in the human genome. PLoS Genet 4: 1–19 doi:10.1371/journal.pgen.1000071
    • (2008) PLoS Genet , vol.4 , pp. 1-19
    • Duret, L.1    Arndt, P.F.2
  • 39
    • 2442651458 scopus 로고    scopus 로고
    • Recombination drives the evolution of GC-content in the human genome
    • Meunier J, Duret L, (2004) Recombination drives the evolution of GC-content in the human genome. Mol Biol Evol 21: 984–990 doi:10.1093/molbev/msh070
    • (2004) Mol Biol Evol , vol.21 , pp. 984-990
    • Meunier, J.1    Duret, L.2
  • 40
    • 84895514565 scopus 로고    scopus 로고
    • A fine-scale recombination map of the human-chimpanzee ancestor reveals faster change in humans than in chimpanzees and a strong impact of GC-biased gene conversion
    • Munch K, Mailund T, Dutheil JY, Schierup MH, (2014) A fine-scale recombination map of the human-chimpanzee ancestor reveals faster change in humans than in chimpanzees and a strong impact of GC-biased gene conversion. Genome Res 24: 467–474 doi:10.1101/gr.158469.113
    • (2014) Genome Res , vol.24 , pp. 467-474
    • Munch, K.1    Mailund, T.2    Dutheil, J.Y.3    Schierup, M.H.4
  • 41
    • 84865208871 scopus 로고    scopus 로고
    • Rate of de novo mutations and the importance of father's age to disease risk
    • Kong A, Frigge ML, Masson G, Besenbacher S, Sulem P, et al. (2012) Rate of de novo mutations and the importance of father's age to disease risk. Nature 488: 471–475 doi:10.1038/nature11396
    • (2012) Nature , vol.488 , pp. 471-475
    • Kong, A.1    Frigge, M.L.2    Masson, G.3    Besenbacher, S.4    Sulem, P.5
  • 42
    • 79959257505 scopus 로고    scopus 로고
    • Variation in human recombination rates and its genetic determinants
    • Fledel-Alon A, Leffler EM, Guan Y, Stephens M, Coop G, et al. (2011) Variation in human recombination rates and its genetic determinants. PLoS One 6: e20321 doi:10.1371/journal.pone.0020321
    • (2011) PLoS One , vol.6 , pp. e20321
    • Fledel-Alon, A.1    Leffler, E.M.2    Guan, Y.3    Stephens, M.4    Coop, G.5
  • 43
    • 84876672046 scopus 로고    scopus 로고
    • DNA binding specificities of the long zinc-finger recombination protein PRDM9
    • Billings T, Parvanov ED, Baker CL, Walker M, Paigen K, et al. (2013) DNA binding specificities of the long zinc-finger recombination protein PRDM9. Genome Biol 14: R35 doi:10.1186/gb-2013-14-4-r35
    • (2013) Genome Biol , vol.14 , pp. R35
    • Billings, T.1    Parvanov, E.D.2    Baker, C.L.3    Walker, M.4    Paigen, K.5
  • 45
    • 0001525977 scopus 로고
    • The average number of generations until fixation of a mutant gene in a finite population
    • Kimura M, Ohta T, (1969) The average number of generations until fixation of a mutant gene in a finite population. Genetics 14: 24–32.
    • (1969) Genetics , vol.14 , pp. 24-32
    • Kimura, M.1    Ohta, T.2
  • 46
    • 55549095155 scopus 로고    scopus 로고
    • Genome-wide nucleotide-level mammalian ancestor reconstruction
    • Paten B, Herrero J, Fitzgerald S, (2008) Genome-wide nucleotide-level mammalian ancestor reconstruction. Genome Res 4: 1829–1843 doi:10.1101/gr.076521.108
    • (2008) Genome Res , vol.4 , pp. 1829-1843
    • Paten, B.1    Herrero, J.2    Fitzgerald, S.3
  • 48
    • 84863230553 scopus 로고    scopus 로고
    • Insights into hominid evolution from the gorilla genome sequence
    • Scally A, Dutheil JY, Hillier LW, Jordan GE, Goodhead I, et al. (2012) Insights into hominid evolution from the gorilla genome sequence. Nature 483: 169–175 doi:10.1038/nature10842
    • (2012) Nature , vol.483 , pp. 169-175
    • Scally, A.1    Dutheil, J.Y.2    Hillier, L.W.3    Jordan, G.E.4    Goodhead, I.5
  • 49
    • 84912120524 scopus 로고    scopus 로고
    • Smit A, Hubly R, Green P (2010) RepeatMasker Open-3.0. http://www.repeatmasker.org.
  • 50
    • 80052142011 scopus 로고    scopus 로고
    • GC-biased gene conversion and selection affect GC content in the Oryza genus (rice)
    • Muyle A, Serres-Giardi L, Ressayre A, Escobar J, Glémin S, (2011) GC-biased gene conversion and selection affect GC content in the Oryza genus (rice). Mol Biol Evol 28: 2695–2706 doi:10.1093/molbev/msr104
    • (2011) Mol Biol Evol , vol.28 , pp. 2695-2706
    • Muyle, A.1    Serres-Giardi, L.2    Ressayre, A.3    Escobar, J.4    Glémin, S.5
  • 51
    • 33646890948 scopus 로고    scopus 로고
    • The GC content of primates and rodents genomes is not at equilibrium: a reply to Antezana
    • Duret L, (2006) The GC content of primates and rodents genomes is not at equilibrium: a reply to Antezana. J Mol Evol 62: 803–806 doi:10.1007/s00239-005-0228-7
    • (2006) J Mol Evol , vol.62 , pp. 803-806
    • Duret, L.1
  • 52
    • 84912076757 scopus 로고    scopus 로고
    • R Development Core Team (2012) R: A language and environment for statistical computing. Vienna: R foundation for statistical computing.
    • (2012)
    • Development Core Team, R.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.