Drive against hotspot motifs in primates implicates the PRDM9 gene in meiotic recombination

Science

Volumn 327, Issue 5967, 2010, Pages 876-879

  Myers, Simon ^a,b   Bowden, Rory ^a,b   Tumian, Afidalina ^a   Bontrop, Ronald E ^c   Freeman, Colin ^b   MacFie, Tammie S ^d,e   McVean, Gil ^a,b   Donnelly, Peter ^a,b  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c BIOMEDICAL PRIMATE RESEARCH CENTRE   (Netherlands)

^d UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^e QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

HISTONE; LYSINE; PRDM 9 PROTEIN; UNCLASSIFIED DRUG; ZINC FINGER PROTEIN;

EUKARYOTE; EVOLUTIONARY THEORY; GENE; GENOME; HUMAN EVOLUTION; PRIMATE; PROTEIN; RECOMBINATION;

AMINO ACID SEQUENCE; ARTICLE; BASE PAIRING; CHIMPANZEE; EUKARYOTE; GENETIC LINKAGE; GENETIC RECOMBINATION; HUMAN; MEIOSIS; METHYLATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIMATE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN MOTIF; SPECIES DIFFERENCE;

ANIMALS; BASE SEQUENCE; CROSSING OVER, GENETIC; DNA; EVOLUTION, MOLECULAR; HISTONE-LYSINE N-METHYLTRANSFERASE; HISTONES; HUMANS; MEIOSIS; METHYLATION; PAN TROGLODYTES; POLYMORPHISM, SINGLE NUCLEOTIDE; RECOMBINATION, GENETIC; SPECIES SPECIFICITY;

EUKARYOTA; PAN; PRIMATES;

EID: 76749155072     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1182363     Document Type: Article

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