Variants of the protein PRDM9 differentially regulate a set of human meiotic recombination hotspots highly active in African populations

Proceedings of the National Academy of Sciences of the United States of America

Volumn 108, Issue 30, 2011, Pages 12378-12383

  Berg, Ingrid L ^a   Neumann, Rita ^a   Sarbajna, Shriparna ^a   Odenthal Hesse, Linda ^a   Butler, Nicola J ^a   Jeffreys, Alec J ^a  

^a UNIVERSITY OF LEICESTER   (United Kingdom)

Author keywords

Conversion; Cross over; Linkage disequilibrium; Meiotic drive; Sperm

Indexed keywords

NUCLEIC ACID BINDING PROTEIN; PROTEIN PRDM9; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ARTICLE; CAUCASIAN; DNA SEQUENCE; GENE CONVERSION; GENE FREQUENCY; GENE LINKAGE DISEQUILIBRIUM; GENETIC RECOMBINATION; GENOTYPE; HUMAN; MALE; MEIOSIS; MEIOTIC RECOMBINATION; NEGRO; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN MOTIF; PROTEIN STRUCTURE; PROTEIN VARIANT; SEMEN ANALYSIS; SINGLE NUCLEOTIDE POLYMORPHISM;

AFRICAN CONTINENTAL ANCESTRY GROUP; ALLELES; AMINO ACID SEQUENCE; BASE SEQUENCE; CROSSING OVER, GENETIC; DNA; EUROPEAN CONTINENTAL ANCESTRY GROUP; GENE CONVERSION; GENE FREQUENCY; GENETIC VARIATION; HISTONE-LYSINE N-METHYLTRANSFERASE; HUMANS; LINKAGE DISEQUILIBRIUM; MALE; MEIOSIS; MOLECULAR SEQUENCE DATA; POLYMORPHISM, SINGLE NUCLEOTIDE; RECOMBINATION, GENETIC; SPERMATOZOA;

EID: 79961097286     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1109531108     Document Type: Article

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